Erythromelalgia with a linear pattern in a 12‐year‐old girl

Abstract

Erythromelalgia is a rare clinical syndrome characterized by erythema, increased temperature, and severe burning pain that can be aggravated by warmth or relieved by cold. Erythromelalgia occurs either as a primary, idiopathic form, or secondary to a number of diseases and conditions. Although fairly well studied in adults, the characteristics, pathogenesis, and natural history are poorly characterized in the pediatric age group. Different therapeutic options have been tried, but no optimal treatment has been suggested for erythromelalgia. We report a rare case of linear erythromelalgia in a 12-year-old girl involving her central body from the peripheral extremities, which seemed to be secondary due to vasculitis. Clinical progress waxed and waned on maintenance aspirin and propranolol.

The role of β‐blockers in dermatological treatment: a review

“…83 Propranolol's therapeutic effect in treating IAP may also be explained by its role as an antagonist for certain serotonin receptors. 87 Placebo effect is a possibility that cannot be ruled out. Treatment is often unsuccessful, and quality of life remains poor.…”

“…86 Recently, a 12-year-old Korean girl suffering from intense pain attacks showed some relief after receiving aspirin and propranolol; however, the symptoms waxed and waned despite maintenance of treatment. 87 Placebo effect is a possibility that cannot be ruled out.…”