Erythromelalgia: Diagnosis and classification

Norton, Jonathan V.; Zager, Emil; Grady, John F.

doi:10.1016/s1067-2516(99)80060-x

Cited by 9 publications

(7 citation statements)

References 13 publications

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“…Recording of definitive skin findings at the time of a patient visit is difficult because erythromelalgia typically shows intermittent symptoms. 4,5 Once diagnosis is confirmed, aspirin is an inexpensive treatment option compared to expensive analgesics. A smartphone "selfie" can accurately record the intermittent signs of erythromelalgia, enabling correct diagnosis of this uncommon condition.…”

Section: Discussionmentioning

confidence: 99%

Intermittent signs of erythromelalgia diagnosed by smartphone selfie

Maita¹,

Kobayashi²,

Osawa³

et al. 2017

IJFCM

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Erythromelalgia, a rare condition associated with myeloproliferative disorders, causes intermittent ischemic pain in the extremities. A 42-year-old woman presented to our hospital with severe bilateral leg pain and intermittent red-violet skin discoloration for 4 years. A Smartphone "selfie" can accurately record the intermittent signs of erythromelalgia, enabling correct diagnosis of this uncommon condition.

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Section: Discussionmentioning

confidence: 99%

Intermittent signs of erythromelalgia diagnosed by smartphone selfie

Maita¹,

Kobayashi²,

Osawa³

et al. 2017

IJFCM

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“…The differential diagnosis includes reflex symptomatic dystrophy, recovery phase of frostbite, hyper‐perfusion phase of Raynaud's, peripheral vascular disease, and cellulitis . Reflex symptomatic dystrophy can be differentiated from erythromelalgia on correlation with recent trauma.…”

Section: Discussionmentioning

confidence: 99%

Erythromelalgia with a linear pattern in a 12‐year‐old girl

Huh

Jung

Eun

et al. 2015

Pediatrics International

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Erythromelalgia is a rare clinical syndrome characterized by erythema, increased temperature, and severe burning pain that can be aggravated by warmth or relieved by cold. Erythromelalgia occurs either as a primary, idiopathic form, or secondary to a number of diseases and conditions. Although fairly well studied in adults, the characteristics, pathogenesis, and natural history are poorly characterized in the pediatric age group. Different therapeutic options have been tried, but no optimal treatment has been suggested for erythromelalgia. We report a rare case of linear erythromelalgia in a 12-year-old girl involving her central body from the peripheral extremities, which seemed to be secondary due to vasculitis. Clinical progress waxed and waned on maintenance aspirin and propranolol.

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“…It is described as acral burning pain, redness, oedema and warmth of the feet and/or hands, which increases with heat and decreases with cold [4]. The pathophysiology is not well understood, but it is thought to be due to an increased blood flow in the microvascular shunts, and tissue hypoxia in the skin [4] This may be primary or secondary to various conditions, including haematological diseases, cardiovascular system diseases, autoimmune diseases and drugs [1,2,3,5].…”

Section: Discussionmentioning

confidence: 99%

“…Symptoms are triggered by physical exertion or a warm environment, and can be relieved by cooling or the elevation of the limbs. This condition can be primary or secondary to systemic disease [1,2,3,4,5,6]. Secondary erythromelalgia usually resolves with treatment of the underlying disease.…”

Section: Introductionmentioning

confidence: 99%

A Case of Erythromelalgia: Good Response to Combination Treatment with Pregabalin and Selective Serotonin Reuptake Inhibitor

2015

J Turk Acad Dermatol

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Observation: Erythromelalgia is a rare entity characterized by episodic acral burning pain, heat and redness in the extremities. Symptoms are triggered by a warm environment and can be relieved by cooling. The pain may be severe enough to disrupt a person's quality of life. The cases in which there is no underlying disease are known as primary, whereas the cases associated with different diseases are known as secondary erythromelalgia. Here, a case of erythromelalgia, secondary to type 2 diabetes mellitus, is presented, with a good response to treatment with a combination of selective serotonin reuptake inhibitors and pregabalin.

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Erythromelalgia: Diagnosis and classification

Cited by 9 publications

References 13 publications

Intermittent signs of erythromelalgia diagnosed by smartphone selfie

Intermittent signs of erythromelalgia diagnosed by smartphone selfie

Erythromelalgia with a linear pattern in a 12‐year‐old girl

A Case of Erythromelalgia: Good Response to Combination Treatment with Pregabalin and Selective Serotonin Reuptake Inhibitor

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