Erythrocyte Stem Cell Kinetics in the Postirradiation Rat

Baum, S. J.

doi:10.2307/3572056

Cited by 11 publications

(4 citation statements)

References 9 publications

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“…Mild to moderate gut damage could have contributed to the shock condition (days 1-2) induced by the burn. A synergistic increase in mortality when sublethal burns follow LD 10 irradiation was reported by Schildt. Sublethal radiation (260 kV-pk X-rays) in combination with burn resulted at best only in an additive effect. However, an LDIo radiatior dose given first followed by thermal injury up to 20 days postirradiation resulted in synergistic increases in mortality to nearly 100 pct.…”

Section: Organizationmentioning

confidence: 59%

“…The effects may tz skin wounds, fractures, and internal injuries. Experiments with the NobleCollip drum reported by Schildt showed that sublethal radiation and LD 10 drum trauma resulted at most in an additive effect whether radiation was first or second. The combination of LDIo radiation and sublethal drum trauma resulted in synergistic increases in mortality, greater when the radiation was first.…”

Section: Blast and Ionizing Radiationmentioning

confidence: 99%

“…This increase was greater than that sustained (30% mortality) when another group of mice was concurrently subjected to the combination of a sublethal mechanical injury and an LDIo scald burn, either being first. Beyond day 0, synergistic increases in mortality are observed only when the animals are subjected to sublethal burn first followed by LDIo mechanical injury one to three days later or LD 10 burn first and sublethal mechanical injury one day later. No synergistic injuries occurred beyond day 3.…”

Section: Other Combined Injuriesmentioning

confidence: 99%

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The Pathophysiology of Combined Radiation Injuries: A Review and Analysis of the Literature on Non-Human Research

Baum¹

1991

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Publ reporting burden for thiscollection of Infom tion is estmlted to average 1 hour p repiolns Including the time for reviewing instructions, serchinig existing data sOurces gathering and maintaining the "dt neded. Approved for public release; distribution is unlimited. ABSTRACT (Maximum 200 words)One hundred and seventy one references applicable to determining the effect of tactical nuclear weapons on military personnel have been reviewed, and the signifi-ant conclusions are reported. The study reviews the scientific literature and focuses on animal experiments published from 1933 to the present time, including a number of German studies and some Soviet research not previously reviewed in English language publications. Recurring themes of the review are the synergistic increase in mortality when injury (burn, wound, bleeding, fracture, etc.) follows irradiation and the reduction in mortality when injury precedes irradiation and/or when antibiotics are administered.

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Section: Organizationmentioning

confidence: 59%

Section: Blast and Ionizing Radiationmentioning

confidence: 99%

Section: Other Combined Injuriesmentioning

confidence: 99%

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The Pathophysiology of Combined Radiation Injuries: A Review and Analysis of the Literature on Non-Human Research

Baum¹

1991

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“…The initial recovery rise in crythrocytic cells and the subsequent oscillation, are caused by the incapability of the injured stem cell population to reiease a sufficient number of cells for crythropoictie recovery while attempting to replace cells killed by radiation through homomorphogenie division. 3 Further modifications during the precursor phase must also be…”

Section: Introductionmentioning

confidence: 99%