Erythrocyte Sedimentation Rate: The Normal Range in the Elderly

Sharland, D. E.

doi:10.1111/j.1532-5415.1980.tb01096.x

Cited by 35 publications

(10 citation statements)

References 5 publications

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“…High values were noted of S-cholesterol in women and of P-creatinine and ESR in both sexes. This confirms the results of some earlier studies [13,15,16], even if the P-creatinine rise is disputed and the S-cholesterol value is thought to decrease after around 60 years of age [2], S-immunoglobulins G and A also showed high median values in the elderly.…”

Section: Discussionsupporting

confidence: 81%

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Blood Components in an Elderly Population

Österlind¹,

Alafuzoff²,

Löfgren³

et al. 1984

Gerontology

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The reference intervals of 18 blood components were established for an elderly population in the 8th decade of life. The most significant findings were a broader range of values for most of the components, lower values of plasma folate and plasma potassium and higher values of erythrocyte sedimentation rate, plasma creatinine and serum cholesterol, the lattermost in women only, compared to younger people.

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Section: Discussionsupporting

confidence: 81%

“…Obviously, there is an urgent need for the establishment of such intervals. Many studies [2,4,7,8,10,13,15,16] have show n that, without doubt, there exist age variations. Despite this, much decision-mak ing in hospitals is based on standard refer ence intervals calculated from young, healthy persons.…”

mentioning

confidence: 99%

Blood Components in an Elderly Population

Österlind¹,

Alafuzoff²,

Löfgren³

et al. 1984

Gerontology

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show abstract

“…It is also known that elderly patients have more comorbidities—diagnosed or occult—that can elevate ESR 15. Furthermore, ESR is influenced by a number of physiological changes, including anaemia, decreased albumin levels, elevated levels of fibrinogen and to a lesser extent α 2 -, β- and χ-globulins, decreased renal function and medication—all of them factors that can be associated with aging 16 – 18. Anaemia occurs in approximately 30% of patients with RA, which is three times the rate in the general population 19.…”

Section: Discussionmentioning

confidence: 99%

Influence of age and gender on the 28-joint Disease Activity Score (DAS28) in rheumatoid arthritis

Radovits

Fransen

Riel

et al. 2008

Annals of the Rheumatic Diseases

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“…Im Hinblick auf Laborparameter ist die Erhöhung der Blutkörperchensenkungsgeschwindigkeit bei alten Menschen wenig hinweisend, weil sie schon physiologisch erhöht ist und keineswegs Ausdruck einer Infektion sein muss (20).…”

Section: Morbididåt Und Mortalitåtunclassified

Infektionen im Alter - was ist anders?

Werner¹,

Kuntsche²

2000

Zeitschrift f�r Gerontologie und Geriatrie

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Infectious diseases are a common cause of increased morbidity and mortality in elderly patients and present a frequent problem in the geriatrician's daily practice. Infections in the elderly are quite different from infections in a younger population. These differences are due to Age-related alterations in immunology Different epidemiology and bacteriology Increased morbidity and mortality Altered clinical presentation Concommittant disability and comorbidity in many older patients Different approaches to therapy. This article is an attempt to discuss these various aspects of infectious disease in the elderly. The most important infections in the elderly are caused by bacteria. Incidence and bacterial spectrum depends on the site of infection and whether the patient is hospitalized, living in a nursing home or in the community. Pneumonia, UTI and pressure ulcer infections are more frequent in patients living in nursing homes than in community dwelling older people. Infections are a frequent cause of hospitalization in elderly people and hospitalization on the other hand is a risk factor for life-threatening nosocomial infections, caused by invasive diagnostic procedures and frequent use of urinary and venous catheters. Infections in the elderly are often accompanied by serious complications as bacteriemia (pneumonia), frequent recurrence (UTI), perforation and abscess (abdominal infections) and severe disability (pressure ulcer infections). Because of these serious and frequent complications mortality of infections is higher in older patients than in younger people. Elderly patients with infectious disease often present in the same way as younger patients do. Many elderly however present with non-specific clinical symptoms and non-specific functional decline which makes an accurate diagnosis difficult and may lead to a life-threatening delay of diagnosis and therapy. In older patients with unexplained functional decline, physicians must be aware of the possibility of a serious infection. Moreover, the physician can not rely on typical signs of infections as fever. In the elderly the fever response is often blunted even in the presence of bacteremia. Leokocytosis may be absent and elevation of acute phase protein is a more reliable marker of infection than elevation of erythrocyte sedimentation rate. Clinical suspicion of bacterial infection in elderly patient should prompt Careful anamnesis and clinical investigation Hospitalization if necessary Diagnostic procedures without delay including blood cultures Immediate empiric antibiotic therapy taking into account the site of infection, if the infection is community acquired or nosocomial and the most likely bacterial spectrum and local resistance factors. The use of broad spectrum antibiotic substances with a low side effect profile and pharmacokinetic properties which are suitable for elderly patients.

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Erythrocyte Sedimentation Rate: The Normal Range in the Elderly

Cited by 35 publications

References 5 publications

Blood Components in an Elderly Population

Blood Components in an Elderly Population

Influence of age and gender on the 28-joint Disease Activity Score (DAS28) in rheumatoid arthritis

Infektionen im Alter - was ist anders?

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