1971
DOI: 10.3181/00379727-138-36000
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Erythrocyte Diphosphopyridine Nucleotidase (NADase) in Paroxysmal Nocturnal Hemoglobinuria

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“…Because acetylcholinesterase activity also seems to be reduced in bone marrow aspirates it has been suggested that the reduction is the result of defective cell membrane synthesis [3]. In both paroxysmal nocturnal hemoglobinuria [107] and ABO disease of the neonate [60], the activities of other membrane enzymes do not seem to be affected. One family in which several members had reduced acetylcholinesterase activity without apparent disease has been described by Johns [57].…”
Section: Erythrocyte Acetylcholinesterase Deficiency In Other Disordersmentioning
confidence: 99%
“…Because acetylcholinesterase activity also seems to be reduced in bone marrow aspirates it has been suggested that the reduction is the result of defective cell membrane synthesis [3]. In both paroxysmal nocturnal hemoglobinuria [107] and ABO disease of the neonate [60], the activities of other membrane enzymes do not seem to be affected. One family in which several members had reduced acetylcholinesterase activity without apparent disease has been described by Johns [57].…”
Section: Erythrocyte Acetylcholinesterase Deficiency In Other Disordersmentioning
confidence: 99%