Erythema nodosum of dental origin

Abstract

The association of erythema nodosum and dental infectious foci has rarely been described in the literature. This report concerns four women who developed erythema nodosum either following dental treatment associated with gingival bleeding or due to infectious dental foci. In these cases, tooth extraction, removal of dental deposits, interrupted pulp treatment, apical periodontitis, or a relicted root were identified as causes of the development of erythema nodosum. Upon admission to the hospital, these patients also presented fever and and a maximally elevated erythrocyte sedimentation rate (ESR). In all instances, surgical treatment of the dental foci and/or administration of antibiotics rapidly led to the regression of the erythema nodosum, as well as to the normalization of body temperature and ESR. The cases described indicate that antecedent dental treatment and the possible presence of infectious dental foci should be considered in the differential diagnosis of erythema nodosum when taking the patient's medical history. This approach may avoid unnecessary, possibly invasive diagnostic procedures and can lead to rapid improvement in the patient's clinical status.

Role of nidi of infection in various skin diseases

“…при этом серьезной доказательной базы по этому вопросу не имеется. В литературе, в основном зарубежной, представлены только клинические наблюдения, которые документируют быстрый регресс симптомов узловатой эритемы после санации ОхИ [61].…”

Focal Infection

“…Focal infection has been cited in arthritis of the knee (Morer, 1975) and infected joint prostheses (Rubin et al, 1976;Schurman et al, 1976;Jacobsen and Murray, 1980;Lindqvist et al, 1989). There has even been a suggestion that dental infectious foci may be involved in other obscure inflammatory disorders, such as erythema nodosum (Kirch and Duhrsen, 1992).…”

Eritema Nodoso – Manifestação Rara De Linfoma Não-Hodgki

“…Em relação à etiologia, o EN pode encontrar-se associado a diferentes patologias sendo as mais comuns a faringite estreptocócica, a sarcoidose, a doença inflamatória intestinal e a tuberculose 4 . Outras causas, mais ou menos frequentes, estão descritas na literatura nomeadamente infeções (micoplasmose, yersiniose, coccidioidomicose, histoplasmose, blastomicose, sífilis, bartonelose, doença de Whipple, infeções dentárias e infeções por VIH, hepatite B, C. trachomatis ou C. pneumoniae), doença de Behçet (entre outras vasculites sistémicas), lúpus eritematoso sistémico, fármacos (nomeadamente contracetivos orais) e gravidez [4][5][6][7][8][9][10][11][12][13][14] . Dentro do grupo das neoplasias estão descritos na literatura alguns casos de associação de linfoma com EN persistente e recorrente 15 .…”