Erythema Multiforme in a Ferret (Mustela putorius furo)

Fisher, Peter G.

doi:10.1016/j.cvex.2013.05.001

Cited by 9 publications

(46 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Erythema multiforme is a multifactorial disease described for humans [ 1 , 24 , 25 ], pigs [ 3 , 4 , 5 , 6 ], dogs [ 7 ] and wild animals, such as ferrets and spotted hyenas [ 8 , 9 ]. The most studied risk factors are drugs, bacterial, viral and fungal infections and/or stress.…”

Section: Discussionmentioning

confidence: 99%

“…All animals were found seropositive for porcine reproductive and respiratory syndrome virus (PRRSV); however, no PRRSV, porcine circovirus type 2 (PCV2) viremia, antibodies against Aujeszky’s disease virus (suid herpesvirus 1, SuHV-1), African swine fever virus or classical swine fever virus were detected [ 6 ]. Moreover, cases of erythema multiforme have been reported in dogs after canine parvovirus-2 infection [ 7 ] and in wild animals, such as ferrets and spotted hyenas [ 8 , 9 ]. In Göttingen minipigs, a syndrome related to erythema multiforme was described, called “Dippity Pig Syndrome”.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Virological Characterization of Pigs with Erythema Multiforme

et al. 2022

View full text Add to dashboard Cite

Erythema multiforme in pigs is an acute, self-limiting disease characterized by red skin areas and often associated with anorexia, fever and respiratory problems. The cause of the disease remains unknown. In a recent study, animals of a commercial breeding herd in Greece were examined, and all animals were found seropositive for porcine reproductive and respiratory syndrome virus (PRRSV). However, neither PRRSV and porcine circovirus type 2 (PCV2) viremia nor antibodies against Aujeszky’s disease virus, African swine fever virus and classical swine fever virus were detected. Here, an extended examination of these pigs was performed on a wide range of porcine viruses using highly sensitive polymerase chain reaction (PCR)-based methods. Affected skin of five animals revealed the presence of porcine lymphotropic herpesvirus-1 (PLHV-1) in all cases, PLHV-2 in one animal and PLHV-3 in four animals. However, neither porcine cytomegalovirus (PCMV) nor porcine circoviruses (PCV1, PCV2, PCV3 and PCV4) were detected. In blood samples, PLHV-1 was present in two animals and PLHV-2, PCV2 and PCV3 in one individual, with PCMV, PCV1 and PCV4 in none of the animals. In one animal, four viruses were found in the blood (PLHV-1, PLHV-2, PCV2 and PCV3). A PRRSV viremia was also not detected. All animals carried porcine endogenous retrovirus C (PERV-C) in their genome, but recombinant PERV-A/C was not detected. The results suggest that porcine viruses may be involved in erythema multiforme in these animals and that further studies are needed to assess the role of these pathogens in the disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Virological Characterization of Pigs with Erythema Multiforme

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Erythema multiforme (EM) is an uncommon T-cellmediated hypersensitivity reaction against antigenically altered keratinocytes that results in keratinocyte apoptosis. [1][2][3][4][5][6][7] The disease is categorised as minor or major based on body surface area affected, number of mucosal surfaces involved and absence or presence of epidermal detachment and systemic illness. 1,3,[5][6][7][8] In humans, clinical lesions have a diagnostic 'targetoid' appearance with three concentric zones: a central dark red area surrounded by a palpable paler pink edematous zone with peripheral erythema.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7] The disease is categorised as minor or major based on body surface area affected, number of mucosal surfaces involved and absence or presence of epidermal detachment and systemic illness. 1,3,[5][6][7][8] In humans, clinical lesions have a diagnostic 'targetoid' appearance with three concentric zones: a central dark red area surrounded by a palpable paler pink edematous zone with peripheral erythema. 1,2,5,6,8 The primary trigger of EM in humans is herpes simplex virus, with fewer cases of Mycoplasma pneumoniae.…”

Section: Introductionmentioning

confidence: 99%

A retrospective study of the range of cutaneous clinical and histological features of erythema multiforme in five ferrets (Mustela putorius furo)

Hess¹,

Trainor²,

Schick³

et al. 2023

Veterinary Dermatology

View full text Add to dashboard Cite

BackgroundErythema multiforme (EM) is an uncommon cutaneous reaction pattern characterised by panepidermal keratinocyte apoptosis with lymphocytic satellitosis, and is reported in domestic animal species, livestock and rarely ferrets.Hypothesis/ObjectivesThe aim of this study was to analyse the spectrum of cutaneous clinical and histological features in ferrets with EM and to evaluate history and treatment outcomes.AnimalsFive client‐owned ferrets with biopsy‐confirmed EM.Materials and MethodsRetrospective review of electronic medical records and histopathological reports from 2002 to 2021. Tissue blocks, haematoxylin and eosin re‐cuts, and unstained slides were collected to review EM lesions and evaluate for infectious agents with special stains. Immunohistochemical staining was performed to assess cases for viral pathogens.ResultsPanepidermal cytotoxic dermatitis consistent with EM was identified in all cases and involved haired skin in four of five and mucous membranes in one of five ferrets. Skin lesions included variably pruritic alopecia, erythema, scaling, crusts and erosions/ulcerations. Histological features included primarily parakeratotic hyperkeratosis, panepidermal keratinocyte apoptosis, lymphocytic satellitosis and interface dermatitis. Superficial colonisation by bacteria, yeasts or by both was a common finding. Four of five ferrets had concurrent adrenal disease, one of which had resolution of skin lesions with deslorelin acetate treatment.Conclusions and Clinical RelevanceAwareness of the distinct clinical and histological features is key to the diagnosis of EM in ferrets. Clinical resolution was observed with gonadotropin‐releasing hormone agonists in two cases, suggesting that adrenal disease should be ruled out as a potential trigger of EM in ferrets.

show abstract

“…Recentemente,Fisher (2013) relatou a desordem em um furão. Em cães, o EM pode ser primário (idiopático) ou secundário à administração de determinadas drogas, infecções, neoplasmas e componentes da dieta(Kersey et al, 2013).Eritema multiforme canino é subdividido em EM maior, EM menor, necrose epidérmica tóxica (NET) e síndrome de Steven-Johnson (SSJ)(Itoh et al, 2006).…”

unclassified

Eritema multiforme limitado à cavidade oral em um cão: relato de caso

Salvagni

Lucio

Mazaro

et al. 2020

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

RESUMO O eritema multiforme é uma doença incomum em cães, que afeta pele e mucosas, cuja etiologia ainda não foi completamente elucidada. Contudo, o envolvimento exclusivo da cavidade oral é considerado raro, tendo sido descrito poucas vezes até o presente momento. O objetivo deste trabalho é descrever um caso de eritema multiforme limitado à cavidade oral em um canino. Um cão, fêmea, Akita, com sete anos de idade, apresentou histórico de ulcerações na cavidade oral e nas laterais da língua, sem alterações cutâneas ou sistêmicas. O diagnóstico definitivo foi realizado por meio do exame histopatológico da mucosa oral, e a terapia imunossupressora empregada mostrou-se eficaz. Embora o eritema multiforme seja considerado incomum na espécie canina, este relato de caso apresenta a forma mais rara da doença, com poucos casos descritos em medicina veterinária.

show abstract

Erythema Multiforme in a Ferret (Mustela putorius furo)

Cited by 9 publications

References 13 publications

Virological Characterization of Pigs with Erythema Multiforme

Virological Characterization of Pigs with Erythema Multiforme

A retrospective study of the range of cutaneous clinical and histological features of erythema multiforme in five ferrets (Mustela putorius furo)

Eritema multiforme limitado à cavidade oral em um cão: relato de caso

Contact Info

Product

Resources

About