Erratum to “The influence of BMP-2 and its mode of delivery on the osteoconductivity of implant surfaces during the early phase of osseointegration” [Biomaterials 28 (2007) 2677–2686]

Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum–bisphosphonate complexes in the treatment of bone tumors: A mini-review

“…The uncontrolled release of growth factors has been related to an accelerated resorption of bone tissue and of the implant. Since growth factor agents can stimulate the degradation as well as the formation of bone (depending on their local concentrations), they could impair the osteoconductivity of the coated-implant surface [82].…”

Biomimetic Nanostructured Apatitic Matrices for Drug Delivery

“…The uncontrolled release of growth factors has, in some instances, been related to an accelerated resorption of bone tissue and of the implant [122]. Since growth factors can stimulate the degradation as well as the formation of bone (depending on their local concentrations), they could impair the osteoconductivity of the coated implant surface [132]. Similarly, bisphosphonate (BP) molecules, by affecting bone remodeling, could also block the bone repair process: the drug at very high concentration could have detrimental effects on the fixation of the implant over longer periods of time.…”

Adsorptive property of albumin and streptokinase on sputtered hydroxyapatite films and its antithrombogenicity

“…This technique enables the HA crystals to grow in hot water below 300 8C, and can also transform any calcium phosphates into HA [12][13][14]. In recent years, it has been suggested that HA be coated using a biomimetic technique [15,16]. Uchida et al suggested that HA coating may be performed using a supersaturated calcium phosphate solution, and they prepared albumin loaded HA films [17].…”