Erratum to: Glutathione and Malondialdehyde Levels in Late Pulmonary Complications of Sulfur Mustard Intoxication

COPD Due to Sulfur Mustard (Mustard Lung)

“…According to the previous pathological studies, it seems that activation of inflammatory cells and generation of reactive oxygen species resulting in oxidative stress be involved (16,17). It has been shown that decreased glutathione and increased serum malondialdehyde levels in mustard lung patients can be an indicator of oxidative-antioxidative system imbalance (16). The previous animal model studies have mentioned that the activation of inflammatory cells are involved in the pathogenesis of SM lung injury (19,20).It is well documented that oxidative antioxidative imbalance may result in oxidative stress and triggering inflammatory process (21).…”

“…According to the previous pathological studies, it seems that activation of inflammatory cells and generation of reactive oxygen species resulting in oxidative stress be involved (16,17). It has been shown that decreased glutathione and increased serum malondialdehyde levels in mustard lung patients can be an indicator of oxidative-antioxidative system imbalance (16).…”

“…The exact mechanism of late pulmonary complication of SM exposure are not fully defined (14).Although the pathogenesis of COPD has completely determined and is mainly dependent on chronic inflammation and oxidative stress following activation of airway inflammatory cells, but there are few studies about the inflammatory basis of mustard lung (8,9,15).The pathological studies have shown that mustard lung is a neutrophilic / lymphocytic disorder (16,17).Also bronchiolar disease with varying degrees of inflammation as the main pathological finding, was demonstrated in a recent pathologic study in patients with sulfur mustard injury (18 ). According to the previous pathological studies, it seems that activation of inflammatory cells and generation of reactive oxygen species resulting in oxidative stress be involved (16,17).…”