Erratum: Fabrication of Chitin/Poly(butylene succinate)/Chondroitin Sulfate Nanoparticles Ternary Composite Hydrogel Scaffold for Skin Tissue Engineering. Polymers, 2014, 6, 2974–2984

Deepthi, S.; Viha, C. V. Sidhy; Chaochai, Thitirat; Furuike, Tetsuya; Tamura, Hiroshi; Rangasamy, Jayakumar

doi:10.3390/polym11030466

Cited by 6 publications

(2 citation statements)

References 1 publication

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“…It has been reported that an enhancement of 3D morphology results in improved mechanical strength and water retention so that a matrix can easily take up nutrients for the establishment of cell adhesion and differentiation. 35,36 AFM Analysis. The surface morphology of the wheat grassreinforced collagen aerogels validates the presence of well-oriented interconnections.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

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Fabrication of Hybrid Collagen Aerogels Reinforced with Wheat Grass Bioactives as Instructive Scaffolds for Collagen Turnover and Angiogenesis for Wound Healing Applications

Govindarajan¹,

Duraipandy²,

Srivatsan³

et al. 2017

ACS Appl. Mater. Interfaces

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The present study illustrates the progress of the wheat grass bioactive-reinforced collagen-based aerogel system as an instructive scaffold for collagen turnover and angiogenesis for wound healing applications. The reinforcement of wheat grass bioactives in collagen resulted in the design and development of aerogels with enhanced physicochemical and biomechanical properties due to the intermolecular interaction between the active growth factors of wheat grass and collagen fibril. Differential scanning calorimetry analysis revealed an enhanced denaturation temperature when compared to those of native collagen aerogels. Fourier transform infrared spectroscopy analysis confirmed that the reinforcement of bioactives in the wheat grass did not affect the structural integrity of the collagen molecule. Additionally, the reinforced biomaterial with a systematic absorptive morphology resulted in a three-dimensional (3D) sponge-like aerogel exhibiting a potent highly oriented 3D structural assembly that showed increased water retention ability and substance permeability that would enable the passage of nutrients and gaseous components for cellular growth. Furthermore, the cumulative effect of the growth factors in wheat grass and the collagen molecule augments the angiogenic ability and collagen production of the aerogel by restoration of the damaged tissue thereby making it a potential 3D wound dressing scaffold. The results were confirmed by in vivo wound healing assays. This study shows the possibility for progress of a biocompatible, biodegradable, and nonadhesive nutraceutical-reinforced collagen aerogel as an instructive scaffold with good antimicrobial properties for collagen turnover and angiogenic response for wound healing applications.

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Section: ■ Results and Discussionmentioning

confidence: 99%

“…In brief, the samples were immersed in distilled water and incubated at room temperature for different time periods. At certain intervals (1,3,5,7,22,24,36, and 48 h), aerogels were removed from water and the wet weight was measured. The swelling behavior of the aerogels was calculated using the following equation (eq 1)…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

Fabrication of Hybrid Collagen Aerogels Reinforced with Wheat Grass Bioactives as Instructive Scaffolds for Collagen Turnover and Angiogenesis for Wound Healing Applications

Govindarajan¹,

Duraipandy²,

Srivatsan³

et al. 2017

ACS Appl. Mater. Interfaces

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Hydrogels based on seafood chitin: From extraction to the development

Zhang,

Mohd Said,

Jing

2023

International Journal of Biological Macromolecules

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Biopolymer-based Scaffolds for Tissue Engineering Applications

Chopra

Kumar

Singh

2021

CDT

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: The tissue engineering is governed by use of cells and polymers. The cells may be accounted for type of tissue to be targeted, while polymers may vary from natural to synthetic. The natural polymers have advantages such as non immunogenic and complex structures that helps in formation of bonds in comparison to the synthetic ones. Various targeted drug delivery systems have been prepared using polymers and cells such as nanoparticles, hydrogels, nanofibers and micro-spheres. The design of scaffolds depends on the negative impact of material used on the human body and they have been prepared either using surface modification technique or neo material synthesis. The dermal substitutes are a distinctive array that aims at replacement of skin part either through grafting or some other means. This review focuses on biomaterials, for their use in tissue engineering. This article shall provide the bird eye view about the scaffolds and dermal substitutes, which are naturally derived

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Erratum: Fabrication of Chitin/Poly(butylene succinate)/Chondroitin Sulfate Nanoparticles Ternary Composite Hydrogel Scaffold for Skin Tissue Engineering. Polymers, 2014, 6, 2974–2984

Abstract: The authors wish to make a change to the published paper [...]

Cited by 6 publications

References 1 publication

Fabrication of Hybrid Collagen Aerogels Reinforced with Wheat Grass Bioactives as Instructive Scaffolds for Collagen Turnover and Angiogenesis for Wound Healing Applications

Fabrication of Hybrid Collagen Aerogels Reinforced with Wheat Grass Bioactives as Instructive Scaffolds for Collagen Turnover and Angiogenesis for Wound Healing Applications

Hydrogels based on seafood chitin: From extraction to the development

Biopolymer-based Scaffolds for Tissue Engineering Applications

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