Erkrankungen an thorakalen Formen der Tularämie bei Arbeitnehmern in Zuckerfabriken

Puntigam, F

doi:10.1007/bf02152053

Cited by 13 publications

(7 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After a week both men developed fever and respiratory symptoms, and later an increase in the agglutination titre to F. tularensis was confirmed. Our present and earlier results support the concept, expressed also by several previous authors (Puntigam, 1960;Jusatz, 1961;Dahlstrand et al, 1971;Pittman et al, 1977) that airborne transmission of tularemia is an occupational risk during farming activities in endemic areas. The source of airborne tularemia may be difficult to identify (Teutsch et al, 1979); in the present series, patient 1 could not remember any source of infection.…”

Section: Resultssupporting

confidence: 92%

See 1 more Smart Citation

Bronchial changes in airborne tularemia

et al. 1986

View full text Add to dashboard Cite

We describe seven typhoidal tularemia patients without ulcers or lymphadenopathy, who underwent diagnostic bronchoscopy. Four patients had had obvious airborne exposure to F. tularensis during farming activities, and the remaining three had respiratory symptoms also. Bronchoscopical findings were pathological in all cases, varying from local to diffuse haemorrhagic inflammation; in one case a granulomatous tumour was seen. Early histopathological changes in three biopsies consisted of haemorrhagic oedema progressing to a non-specific inflammatory reaction, which could still be found 45 days after the onset of symptoms. Granulomatous inflammation, indistinguishable from tuberculosis or sarcoidosis, was seen in four biopsies from two patients, three to seven months after the onset. Most patients had radiographic hilar enlargement. We conclude that transmission of typhoid tularemia usually occurs through inhalation leading to bronchial changes, which correspond skin ulcerations in ulcero-glandular tularemia, the hilar enlargement corresponding to the lymph node component. We emphasize that usage of the term 'typhoidal' tularemia should be discontinued. Instead, tularemia transmitted through inhalation should be called pulmonary or respiratory.

show abstract

Section: Resultssupporting

confidence: 92%

“…1931). Later, reports on epidemics of Tularemia was first described by McCoy in tularemia in sugar workers and farmers have 1911 as a 'plague-like' illness in ground squir-supported this hypothesis (Puntigam, 1960;rels in Tulare County (McCoy, 1911). Francis J usatz > 1 9 6 1 ' Danlstrand et al, 1971).…”

Section: Introductionmentioning

confidence: 95%

Bronchial changes in airborne tularemia

et al. 1986

View full text Add to dashboard Cite

show abstract

“…This is the first study to use WGS to investigate an outbreak of tularemia, and we have used high-quality whole-genome assemblies with maximal nucleotide position coverage for determining exact phylogenetic relationships among F. tularensis isolates. In previously reported respiratory outbreaks [14,16,17,[34][35][36][37][38], F. tularensis cultures were, to the best of our knowledge, not recovered from multiple individuals and hence no molecular investigations were possible. Our conclusions on the genetic ancestry of outbreak genomes were possible only because we used an extensive set of reference genomes.…”

Section: Discussionmentioning

confidence: 99%

An Outbreak of Respiratory Tularemia Caused by Diverse Clones of Francisella tularensis

Johansson

Lärkeryd

Widerström

et al. 2014

Clinical Infectious Diseases

View full text Add to dashboard Cite

The outbreak was caused by diverse clones of F. tularensis that occurred concomitantly, were widespread, and apparently persisted in the environment. Multiple independent acquisitions of F. tularensis from the environment over a short time period suggest that natural outbreaks of respiratory tularemia are triggered by environmental cues. The findings additionally caution against interpreting genome sequence identity for this pathogen as proof of a direct epidemiological link.

show abstract

“…A major human tularemia epidemic occurred in 1959/1960 in sugar factories in Lower Austria, south of the Danube and close to the province of Burgenland. Following the inhalation of contaminated aerosols formed by dead, infected rodents entering the beet-washing process, a total of 577 human cases were recorded [ 80 ]. Further outbreaks of infections were observed after a strong proliferation of field mice ( Microtus arvalis ) promoted by favorable weather conditions like mild winter and hot summer temperatures [ 81 ].…”

Section: Resultsmentioning

confidence: 99%

Tularemia Goes West: Epidemiology of an Emerging Infection in Austria

et al. 2020

View full text Add to dashboard Cite

The zoonotic disease tularemia is caused by the Gram-negative bacterium Francisella tularensis, with the two major subspecies tularensis and holarctica being responsible for infections in humans and animals. The F. tularensis subspecies holarctica is less virulent and prevalent in Europe and Asia. Over the last few centuries, few epidemic outbreaks and low numbers of infections have been registered in the eastern part of Austria, specifically in the provinces of Lower Austria, Burgenland, and Styria. The reported infections were mostly associated with hunting hares and the skinning of carcasses. Within the last decade, ticks have been identified as important vectors in Tyrol and served as first evidence for the spread of F. tularensis to Western Austria. In 2018, the pathogen was detected in hares in the provinces of Tyrol, Vorarlberg, and Salzburg. We presume that F. tularensis is now established in most regions of Austria, and that the investigation of potential host and vector animals should be spotlighted by public institutions. Tularemia in humans presents with various clinical manifestations. As glandular, ulceroglandular, and typhoidal forms occur in Austria, this infectious disease should be considered as a differential diagnosis of unknown fever.

show abstract

Erkrankungen an thorakalen Formen der Tularämie bei Arbeitnehmern in Zuckerfabriken

Cited by 13 publications

References 1 publication

Bronchial changes in airborne tularemia

Bronchial changes in airborne tularemia

An Outbreak of Respiratory Tularemia Caused by Diverse Clones of Francisella tularensis

Tularemia Goes West: Epidemiology of an Emerging Infection in Austria

Contact Info

Product

Resources

About