Ergebnisse Einer Biostatistischen Zusam-Menfassenden Betrachtung über die Erblichen Blutstrukturen des Menschen

Bernstein, Felix

doi:10.1007/bf01736255

Cited by 168 publications

(32 citation statements)

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“…However, Bernstein (1924Bernstein ( , 1925,5),6) Springer (1959) , > andWiener (1966) was conducted in 27 members of A type was seen in 9, 0 type was (including monozygotic twins), and and Bm x A were also found in the family. Children with Bm factor were born in each marriage.…”

Section: Genetical Studies O F Bm Bloodmentioning

confidence: 99%

Genetical Studies of Bm Blood Type on the Twins. V

Ikemoto

Furuhata

1969

Proceedings of the Japan Academy

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Section: Genetical Studies O F Bm Bloodmentioning

confidence: 99%

Genetical Studies of Bm Blood Type on the Twins. V

Ikemoto

Furuhata

1969

Proceedings of the Japan Academy

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“…The genetic concept was corrected and complemented in 1924 by Bernstein with his 3-gene theory [14]. For con- Geserick/Wirth serologically assumed 2-locus model (D/CcEe) could be supported by sequencing of the cDNA, and for certain forensic cases RH genotyping has become possible using PCR-based methods (review in [28]).…”

Section: Further Blood Group Systems Of Erythrocyte Membranesmentioning

confidence: 99%

Genetic Kinship Investigation from Blood Groups to DNA Markers

Geserick¹,

Wirth

2012

Transfus Med Hemother

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The forensic application of hereditary characteristics became possible after the discovery of human blood groups by Karl Landsteiner in 1901. The foundation for their use in kinship investigation was laid by Emil von Dungern and Ludwig Hirschfeld in 1910 by clarification of the inheritance of the ABO groups. Up to the middle of the 20th century further red cell membrane systems were discovered. From the 1920s Fritz Schiff and Georg Strassmann fought for the introduction of blood groups into forensic kinship investigation. A new era of hemogenetics was opened from 1955 as genetic polymorphisms were described in serum proteins. Starting in 1958 there followed the complex HLA system of white blood cells, which from 1963 was joined by polymophisms in erythrocyte enzymes. Therefore, from the 1980s, it was possible to clarify the majority of kinship cases with a combination of conventional markers. From 1990 to 2000 the conventional markers were gradually replaced by the more effective DNA markers. Simultaneously typing shifted from the phenotype level to the genotype level. The genomic structure of con ventional genetic markers could also now be explained. As a reflection of scientific progress the legal situation also changed, particularly in the form of the official guidelines for kinship investigation.

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“…I n both of the above parts the agreement between results observed and expected according to accepted genetic theory, has been examined as described by Taylor & Prior (1938b) and by Stevens (1938 Agreement with the triple allelomorph theory of Bernstein (1924Bernstein ( , 1925) is shown by a x2 value of 0.699 for one degree of freedom, which corresponds to a probability greater than 0.30. The observed and expected numbers, and x2 values for each group, are: …”

Section: The D I S T R I B U T I O N S I N the Aabo B L O O D G R Omentioning

confidence: 99%