Ergebnisse der N1- und N2-Chirurgie beim nichtkleinzelligen Lungenkarzinom

Pfannschmidt, Joachim; Kollmeier, Jens

doi:10.1007/s00104-019-01029-1

Cited by 3 publications

(3 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…34 However, thoracotomy imposes significant trauma on patients, prolonging postoperative recovery and causing dual economic and psychological burdens, especially for older patients with poor recovery and low immunity. 35 Thoracoscopic surgery, widely used in minimally invasive surgeries in recent years, has gradually been applied in thoracic surgeries, particularly in the clinical treatment of lung cancer. 36,37 Wound infection is one of the primary complications of thoracoscopic lobectomy, potentially leading to delayed wound healing and increased risk of systemic infections, directly affecting the patient's psychological and physical health.…”

Section: Discussionmentioning

confidence: 99%

“…Traditional thoracotomy lobectomy has been a common surgical technique for treating lung cancer, with the primary goal of maximally preserving healthy lung tissue while excising the lesion and lymph nodes 34 . However, thoracotomy imposes significant trauma on patients, prolonging postoperative recovery and causing dual economic and psychological burdens, especially for older patients with poor recovery and low immunity 35 . Thoracoscopic surgery, widely used in minimally invasive surgeries in recent years, has gradually been applied in thoracic surgeries, particularly in the clinical treatment of lung cancer 36,37 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of thoracoscopic lobectomy on surgical wound infection in patients with lung cancer: A meta‐analysis

Yang,

Ren,

Xin

et al. 2024

International Wound Journal

View full text Add to dashboard Cite

This meta‐analysis systematically evaluates the impact of thoracoscopic lobectomy on wound infection and complications in lung cancer patients. An extensive computerized search was conducted using PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases for studies comparing thoracoscopic lobectomy with open thoracotomy in the treatment of lung cancer, covering the period up to September 2023. Two researchers independently screened the literature, extracted data and assessed the quality according to predefined inclusion and exclusion criteria. Data analysis was performed using Stata 17.0 software. Ultimately, 21 studies involving 2118 lung cancer surgery patients were included. The analysis revealed that thoracoscopic lobectomy significantly reduced the incidence of wound infections (odds ratio [OR] = 0.22, 95% confidence interval [CI]: 0.13–0.37, p < 0.001) and complications (OR = 0.27, 95% CI: 0.21–0.36, p < 0.001) in lung cancer surgery patients, and also significantly shortened hospital stays (standardized mean difference = −2.07, 95% CI: −2.39 to −1.76, p < 0.001). This study indicates that compared with conventional open thoracotomy, thoracoscopic lobectomy in the treatment of lung cancer reduces the incidence of wound infections and complications and shortens hospital stays, demonstrating significant therapeutic efficacy and warranting broader clinical application.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of thoracoscopic lobectomy on surgical wound infection in patients with lung cancer: A meta‐analysis

Yang,

Ren,

Xin

et al. 2024

International Wound Journal

View full text Add to dashboard Cite

show abstract

Postoperative long-term survival of non-small cell lung cancer patients with skip-N2 metastases

Schlachtenberger¹,

Doerr²,

Menghesha³

et al. 2021

Surgical Oncology

View full text Add to dashboard Cite

Somatic mutations combined with clinical features can predict the postoperative prognosis of stage IIIA lung adenocarcinoma

Li¹,

Lin²,

Li³

et al. 2022

Ann Transl Med

View full text Add to dashboard Cite

Background: Prognostic factors for stage IIIA lung adenocarcinoma (LUAD) are unclear. The current main treatment for stage IIIA LUAD is still controversial. Some Clinicians advocate synchronous chemoradiotherapy as the main treatment for stage IIIA LUAD. In contrast, some clinicians argue that there are still certain patients with stage IIIA LUAD who have a better postoperative prognosis. This study aimed to analyze preoperative factors as well as the association between somatic mutations and prognosis in stage IIIA LUAD [including overall survival (OS) time and the risk of postoperative recurrence]. Methods: This study retrospectively reviewed the data of patients with stage IIIA LUAD who underwent radical resection of lung cancer in the thoracic surgery department of Tianjin Chest Hospital from January 01, 2011 to September 30, 2016. All patients involved in the study provided written informed consent. The associations between OS and DFS and the clinical characteristics as well as somatic mutations of patients were analyzed separately. The Kaplan-Meier method was used for univariate analysis, and survival curves were drawn. Multivariate analysis was performed by the Cox regression model.Results: For univariate analysis, the prognostic factors of OS were the level of preoperative CYFRA21-1, the number of metastatic lymph node stations (NMLS), maximum tumor diameter, EGFR (epidermal growth factor receptor) classical base mutations, and the number of copies of POLE (polymerase epsilon) mutation (NCPM). Preoperative total protein level, preoperative CYFRA21-1 level, the number of metastatic lymph nodes (NMLN), maximum tumor diameter, the number of mutated genes (NMG) in tumor samples, TP53 mutations, and the number of copies of POLE mutation (NCPM) were associated with disease-free survival (DFS). The multivariate analysis showed that the preoperative CYFRA21-1 level, the number of metastatic lymph node stations (NMLS), and EGFR typical base mutations were independent prognostic factors of OS.The number of mutated genes (NMG), EGFR classical base mutations, preoperative NSE level, maximum tumor diameter, and the number of metastatic lymph node stations (NMLS) were independent prognostic factors for DFS. Conclusions:The preoperative level of tumor markers, the number of metastatic lymph node stations, and EGFR typical base mutations are important factors for the prognosis of patients with resectable stage IIIA LUAD.

show abstract

Ergebnisse der N1- und N2-Chirurgie beim nichtkleinzelligen Lungenkarzinom

Cited by 3 publications

References 49 publications

Effects of thoracoscopic lobectomy on surgical wound infection in patients with lung cancer: A meta‐analysis

Effects of thoracoscopic lobectomy on surgical wound infection in patients with lung cancer: A meta‐analysis

Postoperative long-term survival of non-small cell lung cancer patients with skip-N2 metastases

Somatic mutations combined with clinical features can predict the postoperative prognosis of stage IIIA lung adenocarcinoma

Contact Info

Product

Resources

About