Equine placental extract supplement as a night barking remedy in dogs with cognitive dysfunction syndrome

Abstract

With the aging of pet dogs, there has been an increasing trend in senility‐related diseases; additionally, cognitive disorders accompanied by abnormal behaviours are a major burden for owners. Recently, there have been a series of consultations regarding the fact that night barking, which is an abnormal behaviour, remarkably interferes with the owner's sleep and adversely affects the owner's quality of life. However, there has been no effective solution to this problem. In this study, three aged pet dogs diagnosed with dementia were administered an equine placental extract (eqPE) as pet supplement, which has been shown in laboratory models to improve cognitive function. Consequently, night barking ceased 1 week after the administration of eqPE in case 2 and it was observed to decrease in the other two dogs. Furthermore, night barking disappeared 2 and 3 weeks after the administration of eqPE in cases 1 and 3, respectively. No recurrence or exacerbation of night barking was observed in the three cases treated with the eqPE, and no adverse events were observed. These results suggest that eqPE may be useful for improving night barking in pet dogs with dementia, and it is expected to be a new treatment method.

Successful steroid tapering and partial treatment of suspected immune-mediated haemolytic anaemia in a dog with equine placenta extract supplementation: A case report

“…The dose of eqPE used in this study was not accurately determined. In our previous study, we reported that eqPE administered (112 mg/dog sid) to an elderly dog with nocturnal ringing and dementia showed improvement in nocturnal ringing, and no adverse events were observed ( Amano et al ., 2022 ). In the current study, the eqPE dose was 125 mg/dog sid, a 13.6% increase compared to a previous report.…”