Equine glaucoma: a histopathologic retrospective study (1999–2012)

Abstract

Equine glaucoma most commonly occurs secondary to uveitis with Appaloosas and older horses predisposed. Histologic changes are comparable to prior reports of chronic glaucoma; notable findings not previously described in the horse were posterior bowing of the iris base and relative sparing of the superior retina from atrophy associated with elevated IOP.

Equine glaucoma: Where are we now?

“…A diagnosis of secondary glaucoma concurrent with ERU is common and has been reported in 85–91% of cases of glaucoma (Cullen and Grahn ; Curto et al . ).…”

“…A recent retrospective histopathological evaluation of equine glaucoma demonstrated concurrent peripheral anterior synechiae (4% of cases), haemorrhage (4%), proteinaceous debris (30%) or inflammatory infiltrate (65%) in the TM, and cellular or fibrocellular preiridal membranes (61%) (Curto et al . ).…”

“…Age is an important risk factor for glaucoma in horses with a recent study documenting that 65% of equine glaucoma cases were older than 15 years (Curto et al . ). Although females are overrepresented in human and canine cases with glaucoma, there does not appear to be a sex predisposition in equine glaucoma (Tsai et al .…”

Blindness associated with nasal/paranasal lymphoma in a stallion

“…The striking feature of the damage is degeneration and/or atrophy, and there are a variety of possible causes, including trauma, inflammation and glaucoma [2,3,4, 13]. Tumors involving the optic pathway can also be a cause of blindness.…”

“…The various causes of equine blindness associating with degeneration of optic pathway have been reported [2,3,4, 13]. It is relatively uncommon, but the nasal and paranasal sinus tumors have a potential to provoke the visual impairment caused by damage of the optic pathway in relation to their growth and/or invasion.…”