Equine gastric ulceration syndrome: treatment and prevention

Sutton, David

doi:10.1136/vr.g4613

Cited by 4 publications

(4 citation statements)

References 14 publications

(21 reference statements)

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“…But there are few studies on the preventive measures, especially the influence of feeding. The research for the methods to treat or prevent gastric ulcers effectively, without using expensive pharmaceutical agents is a new trend in veterinary medicine (Bonelli et al 2016, Sutton 2016. To meet this growing need, this study aimed to evaluate the effectiveness of a change in the feeding regime as a part of the treatment of EGUS in adult horses.…”

Section: Discussionmentioning

confidence: 99%

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

Böhm¹,

Mitterer²,

Iben³

2018

PHK

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The objective of this study was to find out whether a change from a grain-rich concentrated feed to a grain-free, fibre-and fatenriched concentrated diet (FFD), leads to an improvement in gastric ulcers in horses. The experiment was conducted as a prospective experimental study. Thirty-four adult horses with gastric lesions-six mares and 28 geldings-fulfilled the inclusion criteria of this study. The average age was 11± 4 (mean ± SD) years and the horses weighed between 358 kg and 697 kg. Twenty horses were fed the FFD, while 14 horses were controls (C) and received their usual concentrated feed. Each horse underwent gastroscopy twice, at an interval of eight weeks. An independent evaluation of the examination and the scoring of the lesions, using the Equine Gastric Ulcer Council 0-4 scoring system for equine gastric ulcer syndrome (EGUS), was performed by an experienced gastroscopist. The horses with EGUS scores ≥ 3 received additional omeprazole at the recommended dosage for 14 days. The horses of the FFD group were adapted to the new diet whereas the control group received their usual concentrate. In the control group, only the amounts of hay and concentrate were adjusted to the requirement of the respective horse. After the change of the ration, the starch intake (FFD 0.09 ± 0.05 g/kg BW; C 1.38 ± 0.62 g/kg BW) was significantly different. However, there was no difference concerning the hay intake (FFD 21.2 ± 3.5 g/kg BW/day; C 23.3 ± 5.1 g/kg BW/day), the Ca intake (FFD 0.129± 0.034 g/kg BW/day; C 0.112 ± 0.019 g/kg BW/day), the Mg intake (FFD 0.042 ± 0.009 g/kg BW/day; C 0.042 ± 0.011g/kg BW/day) or the intake of the praecaecal digestible protein (FFD 1.42 ± 0.38 g/kg BW/day; C 1.58 ± 0.39 g/kg BW/day). The prevalence and severity of the mucosal lesions significantly decreased in the FFD group (p<0.001). No significant correlation between the EGUS and the other risk factors, such as workload, behaviour or typical symptoms was found in this study. The change of the concentrated feed to FFD improved the gastric ulcerations in both squamous and glandular mucosa.

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Section: Discussionmentioning

confidence: 99%

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

Böhm¹,

Mitterer²,

Iben³

2018

PHK

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“…). In addition, even if a product is shown to work under precise experimental conditions, there is no way to know if it works under real field conditions where multifactorial risk factors may be present (Sutton ). Alternatively, if it does not work under experimental conditions, it may or may not work under field conditions.…”

Section: Dietary Supplementsmentioning

confidence: 99%

“…Many of these products have not been tested in horses, and this is a controversial area for many reasons, not least that in many parts of the world legislation restricts the claims that can be made for such products, which perhaps reduces the likelihood of studies being undertaken to support efficacy (Harris et al 2013). In addition, even if a product is shown to work under precise experimental conditions, there is no way to know if it works under real field conditions where multifactorial risk factors may be present (Sutton 2014…”

Section: Dietary Supplementsmentioning

confidence: 99%

Nutritional management of gastric ulceration

Andrews

Larson

Harris³

2015

Equine Veterinary Education

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Summary Gastric ulcers are common in horses and equine gastric ulcer syndrome describes ulcers in the distal oesophagus, nonglandular and glandular stomach as well as the proximal duodenum. Ulcers in the distal oesophagus and nonglandular region of the stomach are probably caused by hydrochloric acid, whereas ulcers in the glandular stomach and proximal duodenum are likely to be caused by a breakdown in the mucosal defence mechanisms. Regardless of the location of ulcers, initial treatment with pharmacological agents is necessary to suppress hydrochloric acid; however, nutrition and management changes are required to maintain ulcer healing and help prevent recurrence. In addition, many dietary supplements have been marketed to help maintain stomach health and some scientific data on their effects on gastric ulcer scores and gastric juice pH are presented.

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“…Currently, therapeutic agents such as H 2 receptor antagonists and proton pump inhibitors are used to treat gastric ulcers. However, these drugs need to be administered for long periods (3 to 4 weeks), and continuous prophylactic administration of half the dose must be performed even if the gastric ulcer has healed [4,8,15]. Therefore, it is necessary to prevent the development of gastric ulcers in horses by adjusting the pH of the stomach and suppressing gastric mucosal damage.…”

mentioning

confidence: 99%

Effect of a novel rice fermented extract on gastric ulcers in horses

Sasaki

Nishi

Fujiwara

et al. 2021

JES

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Gastric ulcers cause appetite loss, poor body condition, and colic in horses. This study investigated the protective effect of a rice fermented extract on the gastric mucosa in 17 healthy Thoroughbreds. For one month, horses in the rice fermented extract (nine horses) and control (eight horses) groups were orally administered a rice fermented extract (100%; 0.2 ml/kg, SID) and tap water (0.2 ml/kg), respectively. Gastric endoscopic images were obtained before and one month after rice fermented extract administration. The gastric ulcer score was lower after administration (median, 1; maximum, 2; minimum, 1) than before administration (median, 4; maximum, 4; minimum, 3) in the rice fermented extract group (P<0.05). In conclusion, the administration of a rice fermented extract for one month improves gastric mucosal lesions in Thoroughbreds with gastric ulcers.

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Equine gastric ulceration syndrome: treatment and prevention

Abstract: An example of glandular mucosal ulceration, showing an inflamed pylorus with a deep ulcer in the final stages of healing, following four months of medication. Chronic weight loss was the major presenting problem in this horse

Cited by 4 publications

References 14 publications

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

The impact of feeding a high-fibre and high-fat concentrated diet on the recovery of horses suffering from gastric ulcers

Nutritional management of gastric ulceration

Effect of a novel rice fermented extract on gastric ulcers in horses

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