EQ-5D-5L in the General German Population: Comparison and Evaluation of Three Yearly Cross-Section Surveys

Huber, Manuel B.; Reitmeir, Peter; Vogelmann, Martin; Leidl, Reiner

doi:10.3390/ijerph13030343

Cited by 36 publications

(43 citation statements)

References 34 publications

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“…The VAS values in this study can also be compared with earlier and methodologically identical studies from 2012, 2013, and 2014, which show relatively high VAS means (83.3; 84.9; 84.8) [16]. The comparison with 2012 data (Figure 5) revealed that health state valuation remained quite stable.…”

Section: Discussionsupporting

confidence: 65%

Health-Related Quality of Life of the General German Population in 2015: Results from the EQ-5D-5L

Huber

Felix

Vogelmann³

et al. 2017

IJERPH

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The EQ-5D-5L is a widely used generic instrument to measure health-related quality of life. This study evaluates health perception in a representative sample of the general German population from 2015. To compare results over time, a component analysis technique was used that separates changes in the description and valuation of health states. The whole sample and also subgroups, stratified by sociodemographic parameters as well as disease affliction, were analyzed. In total, 2040 questionnaires (48.4% male, mean age 47.3 year) were included. The dimension with the lowest number of reported problems was self-care (93.0% without problems), and the dimension with the highest proportion of impairment was pain/discomfort (71.2% without problems). Some 64.3% of the study population were identified as problem-free. The visual analog scale (VAS) mean for all participants was 85.1. Low education was connected with significantly lower VAS scores, but the effect was small. Depression, heart disease, and diabetes had a strong significant negative effect on reported VAS means. Results were slightly better than those in a similar 2012 survey; the most important driver was the increase in the share of the study population that reported to be problem-free. In international comparisons, health perception of the general German population is relatively high and, compared with previous German studies, fairly stable over recent years. Elderly and sick people continue to report significant reductions in perceived health states.

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Section: Discussionsupporting

confidence: 65%

Health-Related Quality of Life of the General German Population in 2015: Results from the EQ-5D-5L

Huber

Felix

Vogelmann³

et al. 2017

IJERPH

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“…Moreover, further analyses are planned within the present data set focusing on the predictors of QL, such as lesion site (especially sites of high cosmetic importance), number of lesions and treatment types. Another important research question for the future is a thorough comparison between NMSC/AK patients with reference data from the general population and from other patient groups …”

Section: Discussionmentioning

confidence: 99%

“…Another important research question for the future is a thorough comparison between NMSC/AK patients with reference data from the general population and from other patient groups. [51][52][53][54] In conclusion, we analysed QL data from 1184 patients with NMSC and AK, which makes this study one of the largest reported PROM studies in the field of dermatology. Our results suggest that disease progression from AK to SCC is associated with a significant reduction in QL.…”

Section: Discussionmentioning

confidence: 99%

Patient‐reported health outcomes in patients with non‐melanoma skin cancer and actinic keratosis: results from a large‐scale observational study analysing effects of diagnoses and disease progression

Philipp‐Dormston¹,

Müller

Novak

et al. 2018

Acad Dermatol Venereol

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BackgroundNon‐melanoma skin cancer (NMSC) and actinic keratosis (AK) are very common among fair‐skinned individuals. A disease continuum from AK to squamous cell carcinoma (SCC) has been frequently postulated. AK and NMSC may influence quality of life (QL) of patients, and it can be suspected that disease progression entails a QL reduction. The purpose of this study was to document QL in patients with NMSC and AK using the health‐outcome questionnaire EQ‐5D‐5L.MethodsThe study was designed as a non‐interventional, prospective, cross‐sectional study. Patients with AK, SCC, basal cell carcinoma (BCC) or multiple diagnoses were enrolled in this study in 29 dermatological centres across Germany. Patients were asked to complete the EQ‐5D‐5L (compromising EQ Index and EQ VAS), and the dermatologists provided diagnosis, disease history and treatment data.ResultsA total of 1184 patients were enrolled and diagnosed as follows: 73% AK, 49% BCC and 17% SCC. 66% had a single diagnosis, 28% two different diagnoses and 6% three different diagnoses. QL was strongly associated with patients’ diagnosis. Patients with a single AK diagnosis had significantly higher mean EQ VAS (78) than patients with BCC (74), SCC (72), and BCC plus SCC (69), P < 0.050. When the effects of disease progression were calculated, patients with AK plus SCC reported significantly less mean EQ VAS (71) than patients with a single AK diagnosis (78), P < 0.011.ConclusionsWhile rarely being imminently life‐threatening, NMSC and AK have an impact on QL as quantified by the EQ‐5D‐5L. This impact is associated with diagnosis (AK vs. NMSC) and clinical progression (AK vs. AK plus SCC). Both lead to a clear decline in QL. This shows that disease progression is perceived and judged as detrimental by patients and that AK and NMSC should be diligently treated to preserve and restore QL.

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“…The EQ-5D-5L questions, including the VAS, were administered by written questionnaire. From 2012 to 2014, the surveys produced 6074 respondents; the methods and results have been presented in detail elsewhere [26]. The 2015 survey was conducted in the same way, adding another 2040 respondents and generally stable baseline results; for detail, see the study by Huber et al [27].…”

Section: Methodsmentioning

confidence: 99%

An Experience-Based Value Set for the EQ-5D-5L in Germany

Leidl¹,

Reitmeir

2017

Value in Health

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EQ-5D-5L in the General German Population: Comparison and Evaluation of Three Yearly Cross-Section Surveys

Cited by 36 publications

References 34 publications

Health-Related Quality of Life of the General German Population in 2015: Results from the EQ-5D-5L

Health-Related Quality of Life of the General German Population in 2015: Results from the EQ-5D-5L

Patient‐reported health outcomes in patients with non‐melanoma skin cancer and actinic keratosis: results from a large‐scale observational study analysing effects of diagnoses and disease progression

An Experience-Based Value Set for the EQ-5D-5L in Germany

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