Epithelioid trophoblastic tumor

Keser, Sevinç Hallaç; Kökten, Şermin Çoban; Çakır, Çağlar; Sensu, Sibel; Büyükbayrak, Esra Eşim; Karadayi, Nimet

doi:10.1016/j.tjog.2015.08.020

Cited by 12 publications

(18 citation statements)

References 11 publications

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“…Epithelioid trophoblastic tumor is an exceedingly rare tumor, seen mostly in reproductive-aged women [6]; it can be a sequel of any gestational event. Approximately one-third of cases arise following a spontaneous abortion or hydatidiform mole, whereas the majority occur after a full-term pregnancy [2,5,7].…”

Section: Case Discussionmentioning

confidence: 99%

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Keratoacanthoma-like nodules as first manifestation of metastatic epithelioid trophoblastic tumor

Gil

Elvas²,

Raposo³

et al. 2019

Dermatology Online Journal

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Section: Case Discussionmentioning

confidence: 99%

“…The average interval from the antecedent gestational event to presentation varies, ranging from two months to as long as 18 years [2,4,5]. Epithelioid trophoblastic tumor can present in both intrauterine and extrauterine sites [2,6]. Most often the uterus is the primary site (40%), followed by the cervix (31%).…”

Section: Case Discussionmentioning

confidence: 99%

Keratoacanthoma-like nodules as first manifestation of metastatic epithelioid trophoblastic tumor

Gil

Elvas²,

Raposo³

et al. 2019

Dermatology Online Journal

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“…Epithelioid trophoblastic tumors are rare types of GTN, which are mostly seen in reproductive females aged between 15 and 48 years (mean 36.1 per year). [2] They can be observed after a normal pregnancy in 67% of cases. In addition, these tumors can be detected after spontaneous abortion and hydatidiform mole.…”

Section: Discussionmentioning

confidence: 99%

“…[1] To date, nearly 100 ETT cases have been reported in the literature; however, there is no clear information about how many of them metastasize to the lung. [2] In this article, we present a case of ETT metastasis in bilateral lung that was treated with surgical resection.…”

mentioning

confidence: 99%

A rare tumor metastasis of bilateral lung: Epithelioid trophoblastic tumor

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Ergönül

et al. 2018

Turk Gogus Kalp Dama

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Öyküsünde gestasyonel trofoblastik tümör cerrahisi olan 44 yaşında bir kadın hasta, her iki akciğerde yavaş progresyon gösteren kistikkaviter lezyon saptanması üzerine kliniğimize sevk edildi. Tanı ve tedavi amaçlı iki taraflı cerrahi uygulanmasına karar verilen hastaya önce sol üst lobektomi, bir ay sonra sağ alt lobektomi yapıldı. Her iki ameliyat sırasında edinilen numunelerin histopatolojik inceleme sonuçları bir "epiteloid trofoblastik tümör metastazı" olarak bildirildi. Sol üst lobdaki tümör içinde aynı zamanda aspergilloma izlendi. Gestasyonel torfoblastik tümörlerin çok nadir bir üyesi olan epiteloid trofoblastik tümörler uzak organ metastazı yapabilir. Çoğunlukla kemoterapiye dirençli olan bu olgularda cerrahi tedavi önemini korumaktadır. Anah tar söz cük ler: İki taraflı anatomik akciğer rezeksiyonu; kaviter akciğer metastazı; epiteloid trofoblastik tümör.

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“…ITTs mainly occur in women of childbearing age, but there are also reports of postmenopausal patients with ITT. ITTs can be secondary to multiple pregnancy outcomes, including full-term pregnancy, miscarriage, ectopic pregnancy and molar pregnancy [2][3] . The time of onset varies from the previous pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Application value of contrast-enhanced ultrasound in the diagnosis of intermediate trophoblastic tumours

Zhu

Zhou

2021

Preprint

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Background Through the research and analysis of colour Doppler ultrasound images (CDFIs) and contrast-enhanced ultrasonography (CEUS) images of intermediate trophoblastic tumours (ITTs), the ultrasound characteristics and CEUS perfusion characteristics are summarized, and these findings can provide a reference for the correct diagnosis of ITTs. Methods Seven ITT patients were diagnosed and treated in our institution from January 2016 to August 2020, and their clinical characteristics and ultrasound image characteristics were studied. Results The most common clinical symptoms of an ITT are vaginal bleeding and menopause. In the study, 6 patients had a history of menopause, 5 patients had irregular vaginal bleeding, and 1 patient was asymptomatic. The serum ß-human chorionic gonadotropin (ß-hCG) level was mainly a low-grade increase, and the average level was approximately 8167 IU/L. However, the ß-hCG level in one patient with lung metastasis was not high (53.2 IU/L), and the ß-hCG level in the other patient with ovarian and bladder metastases was high (55422.2 IU/L). In grey-scale ultrasound, ITTs can be divided into 3 types: type I, where most of the lesions protrude into the uterine cavity (2 patients); type II, where the lesions are partly located in the uterine cavity and partly in the muscle layer (3 patients); and type III, where the lesions are limited to the myometrium (2 patients). The internal echo of the lesion can be divided into solid and cystic-solid echo. CDFI shows that blood flow signals from minimal to abundant. The enhancement mode of CEUS is mainly regional enhancement (5 patients), the arterial phase is mainly slow and equal-slightly high enhancement (6 patients), and the enhancement boundary is not clear (6 patients). Conclusions Certain characteristic changes in CEUS of ITTs, combined with clinical features, can provide help for the accurate diagnosis of ITT.

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Epithelioid trophoblastic tumor

Abstract: Because precise differential diagnosis will alter the therapeutic approach and prognosis, it is necessary for treating physicians to be aware of these unusual presentations.

Cited by 12 publications

References 11 publications

Keratoacanthoma-like nodules as first manifestation of metastatic epithelioid trophoblastic tumor

Keratoacanthoma-like nodules as first manifestation of metastatic epithelioid trophoblastic tumor

A rare tumor metastasis of bilateral lung: Epithelioid trophoblastic tumor

Application value of contrast-enhanced ultrasound in the diagnosis of intermediate trophoblastic tumours

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