Epithelial salivary gland tumors in children: A twenty-five-year experience of 122 patients

Tumors in the parotid are not relatively more often malignant in children than in adults

“…This is in accordance with most studies [2][3][4]6,9,12] but in contrast to others [7,16]. This difference may be explained by the limited data regarding this particular demographic in general and by the fact that most previous reports are single-center studies and therefore to some extent selected.…”

“…Our finding with acinic cell carcinoma as the most common of the malignant SGT differs from international studies where the mucoepidermoid carcinoma is the most common [1][2][3][4]7,[9][10][11][12][14][15][16] and from a Danish study that showed adenoid cystic carcinoma to be the most common malignant SGT among the entire population [17]. However, our number of patients with malignancies is small.…”

“…Salivary gland tumors (SGT) are especially rare in children and very little data has been reported in the literature regarding populationbased demographic data. Most studies are single-center experiences [1][2][3][4][5][6][7][8] and are therefore selected materials. We want to gain a better understanding of the true incidence of these tumors as well as the histopathologic distribution in a nationwide population.…”

Comparison between immunohistochemical expression of Ki-67 and MCM-3 in major salivary gland epithelial tumors in children and adolescents. Preliminary study

“…It is suggested that in the pediatric population, like in adults, the parotid gland is the most common site involved by pleomorphic adenoma. When a tumor is situated in the submandibular gland it is also mostly a benign lesion, which is not in agreement with studies on adults [2,11,12].…”

“…Because of low grade histology, in most cases of major salivary gland malignant epithelial tumors in children and adolescents, elective neck dissections are not necessary. If possible, function of the facial nerve and its branches should always be preserved [12,13].…”