Epithelial cyst of the soft palate

Çaylaklı, Fatma; Yavûz, Halûk; Bolat, Fılız; Özer, Fulya; Özgirgin, Nuri

doi:10.1016/j.ijporl.2004.11.014

Cited by 8 publications

(17 citation statements)

References 6 publications

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“…The clinical evidence that supports fusion includes the presence of epithelial cysts in the soft palate. The prevalence of midline palatal cysts or Epstein's pearls is high in the hard palate (54% of newborns (Monteagudo et al 2012) but much rarer in the soft palate (Caylakli et al 2005;Tsai et al 2013). A Japanese study found epithelial cysts in the midline of the soft palate in the early fetal period (53-55 days post-conception; (Kitamura, 1966), so perhaps many of these resolve prior to birth.…”

Section: Introductionmentioning

confidence: 99%

Analysis of human soft palate morphogenesis supports regional regulation of palatal fusion

et al. 2015

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It is essential to complete palate closure at the correct time during fetal development, otherwise a serious malformation, cleft palate, will ensue. The steps in palate formation in humans take place between the 7th and 12th week and consist of outgrowth of palatal shelves from the paired maxillary prominences, reorientation of the shelves from vertical to horizontal, apposition of the medial surfaces, formation of a bilayered seam, degradation of the seam and bridging of mesenchyme. However, in the soft palate, the mechanism of closure is unclear. In previous studies it is possible to find support for both fusion and the alternative mechanism of merging. Here we densely sample the late embryonic-early fetal period between 54 and 74 days post-conception to determine the timing and mechanism of soft palate closure. We found the epithelial seam extends throughout the soft palates of 57-day specimens. Cytokeratin antibody staining detected the medial edge epithelium and distinguished clearly that cells in the midline retained their epithelial character. Compared with the hard palate, the epithelium is more rapidly degraded in the soft palate and only persists in the most posterior regions at 64 days. Our results are consistent with the soft palate following a developmentally more rapid program of fusion than the hard palate. Importantly, the two regions of the palate appear to be independently regulated and have their own internal clocks regulating the timing of seam removal. Considering data from human genetic and mouse studies, distinct anterior-posterior signaling mechanisms are likely to be at play in the human fetal palate.

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Section: Introductionmentioning

confidence: 99%

Analysis of human soft palate morphogenesis supports regional regulation of palatal fusion

et al. 2015

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“…[1][2][3][4][5][6][7][8][9] One article was in Polish 3 and therefore not included, leaving 10 patients total. 1,6,7 In those for whom there was follow-up information, no recurrences or speech problems were noted. One patient had a dermoid cyst, while the remaining patients had epidermoid cysts.…”

Section: Review Of Literaturementioning

confidence: 99%

“…6 Epidermoid and dermoid cysts occur about 1.6% of the time in the oral cavity. [1][2][3][4][5][6][7][8][9] In this case, we present our experience with a 28-month-old who was found to have a symptomatic large epidermoid cyst of her right soft palate. [1][2][3][4][5][6][7][8][9] In this case, we present our experience with a 28-month-old who was found to have a symptomatic large epidermoid cyst of her right soft palate.…”

Section: Introductionmentioning

confidence: 99%

Epidermoid Cyst of the Soft Palate in a 2-Year-Old

Alcorn

Pollock

Kazahaya

et al. 2014

Clin Pediatr (Phila)

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“…Most of the lesions are asymptomatic, but in some cases, enlarged cystic lesions can cause air way obstruction, sonorous respiration, gagging or dysphagia [5,9]. The surgical excision of the epithelial cyst is diagnostic and treatment method at the same time, and no obvious complications have been reported [6,7].…”

Section: Case Reportmentioning

confidence: 99%

“…These lesions can be found on any part of the body, although 6.9% of them appear at head and neck area and only 1.6% are seen in the oral cavity [1,2]. Most cysts occurring in the oral cavity are located at the anterior part of the mouth floor, and the soft palate or uvula is an unusual site [3][4][5][6]. There is no report of an epithelial cyst of the uvula in a cleft palate patient.…”

Section: Introductionmentioning

confidence: 99%

Epithelial Cyst of the Uvula with Unilateral Complete Cleft Lip and Palate

Kim¹,

Yang²,

Leem³

et al. 2014

The Journal Of Korean Association of Maxillofacial Plastic and

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Epithelial cysts are benign epithelium-lined lesions that contain fluid or semisolid material. Most epithelial cysts in the oral cavity occur in the anterior part of the mouth floor. Cysts arising on the uvula in a cleft palate patient are rare. Intraoral examination in a 14-month-old boy with a complete cleft lip and palate revealed a cystic lesion on the right uvula. The lesion was excised and push-back palatorrhaphy with Z-plasty on the uvula was performed. Histopathological examination diagnosed an epithelial cyst. We report a case of an epithelial cyst of uvula in a patient with a unilateral complete cleft lip and palate.

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Epithelial cyst of the soft palate

Cited by 8 publications

References 6 publications

Analysis of human soft palate morphogenesis supports regional regulation of palatal fusion

Analysis of human soft palate morphogenesis supports regional regulation of palatal fusion

Epidermoid Cyst of the Soft Palate in a 2-Year-Old

Epithelial Cyst of the Uvula with Unilateral Complete Cleft Lip and Palate

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