Epistaxis and catastrophic nasal bleeding

Al-Bar, Mohammad H.

doi:10.1016/j.otot.2014.02.010

Cited by 5 publications

(5 citation statements)

References 32 publications

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“…Интенсивность ХЛ регистрировали на от-ечественном хемилюминотестере ЛТ-1 производ-ства НПО «Люмин», оснащенном компьютерным обеспечением по методу Ю. В. Владимирова [19], в основе которого лежит способность испытуемой системы к сверхслабому свечению.…”

Section: материалы и методыunclassified

Potential of Antioxidant Protection in Patients With Epistaxis

Владимировна¹,

Колмакова²,

Smirnova³

2017

Kuban. nauсh. med. vestnik

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ПОÒЕНЦИАЛ АНÒИОКСИДАНÒНОЙ ЗАЩИÒЫ У БОЛЬНЫХ С НОСОÂЫМИ КРОÂОÒЕЧЕНИЯМИ Федерации, пер. Нахичеванский, д 29, Ростов-на-Дону, Россия, 344022 АННОТАЦИЯТяжесть состояния больных при носовых кровотечениях(НК) зависит не только от объема кровопотери, но и от степени компенсации гипоксии, сопровождающей кровопотерю.Цель. Изучить антиоксидантные (АО) свойства сыворотки крови и интенсивность процессов перекисного окис-ления липидов (ПОЛ) в мембранах эритроцитов больных с НК различной степени тяжести.Материалы и методы. Исследовали 82 больных с носовыми кровотечениями различной степени тяжести. Ан-тиоксидантную активность сыворотки крови больных изучали методом хемилюминесценции, индуцированной ио-нами двухвалентного железа. Процессы перекисного окисления липидов изучали, оценивая активность ферментов антиоксидантной защиты -супероксиддисмутазы (СОД) и суммарную пероксидазную активность в эритроцитах крови, а также содержание в эритроцитах конечного продукта ПОЛ -малонового диальдегида (МДА).Результаты. Установлено, что что потенциал антиоксидантной защиты сыворотки и форменных элементов крови являются одним из важнейших звеньев патогенеза НК.Заключение. Высокая емкость антиоксидантной защиты может существенно снизить риск развития необрати-мых изменений в эритроцитах и развития клинических признаков глубокой тканевой гипоксии при НК. POTENTIAL OF ANTIOXIDANT PROTECTION IN PATIENTS WITH EPISTAXIS ABSTRACTThe status of patients with nose bleedings (NB) depends not only on the volume of blood loss, but also on the degree of compensation for hypoxia accompanying hemorrhage.Aim. The main aim of our research was to study the antioxidant properties of blood serum and the intensity of LPO processes in erythrocyte membranes of patients with epistaxis of varying severity.Materials and methods. 82 patients with nose bleeding of varying severity were examined. The antioxidant activity of the blood serum of patients was studied by the chemiluminescence method induced by divalent iron ions. The processes of lipid peroxidation were studied by evaluating the activity of antioxidant defense enzymes -superoxide dismutase (SOD) and total peroxidase activity in blood erythrocytes, as well as the content of the final product of LPO-malonic dialdehyde (MDA) in erythrocytes.Results. It has been established that the potential of antioxidantprotection of serum and formed elements of blood is one of the most important links in the pathogenesis of NB.Conclusion. High capacity of antioxidant protection can significantly reduce the risk of irreversible changes in erythrocytes and the development of clinical signs of deep tissue hypoxia in patients with epistaxis.

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Section: материалы и методыunclassified

Potential of Antioxidant Protection in Patients With Epistaxis

Владимировна¹,

Колмакова²,

Smirnova³

2017

Kuban. nauсh. med. vestnik

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“…The nasal cavities have two areas of blood supply with anastomoses from both the internal and external carotid arteries . The anterior nasal septum, where 90% of bleeding comes from, is supplied by the nasal branch of the superior ethmoid artery and septal branches of the anterior ethmoidal and superior labial arteries.…”

Section: Anatomymentioning

confidence: 99%

“…The exact reasons for a predisposition to epistaxis are often not clear, however, localized varices, telangiectasias, aneurysms, or superficially located vessels are all possibilities . Local trauma from digital manipulation or a blow during an assault is a common cause of epistaxis, as may be septal deviation from surgery or previous trauma.…”

Section: Etiologymentioning

confidence: 99%

“…Most cases are of minimal significance and cease spontaneously without medical intervention. While conservative management with external pressure, packing, the use of vasoconstrictive agents, and/or electrocautery is usually effective in cases presenting to hospital, occasionally endoscopic ligation or embolization of nasal vessels such as the sphenopalatine branch of the internal maxillary artery that arises from the external carotid artery is required . Very rarely, however, epistaxis may be associated with torrential and lethal blood loss, resulting in cases coming to medicolegal attention.…”

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confidence: 99%

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Lethal Epistaxis

Byard

2016

Journal of Forensic Sciences

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Epistaxis or nosebleed refers to bleeding from the nostrils, nasal cavity, or nasopharynx. Occasional cases may present with torrential lethal hemorrhage. Three cases are reported to demonstrate particular features: Case 1: A 51-year-old woman with lethal epistaxis with no obvious bleeding source; Case 2: A 77-year-old man with treated nasopharyngeal carcinoma who died from epistaxis arising from a markedly neovascularized tumor bed; Case 3: A 2-year-old boy with hemophilia B who died from epistaxis with airway obstruction in addition to gastrointestinal bleeding. Epistaxis may be associated with trauma, tumors, vascular malformations, bleeding diatheses, infections, pregnancy, endometriosis, and a variety of different drugs. Careful dissection of the nasal cavity is required to locate the site of hemorrhage and to identify any predisposing conditions. This may be guided by postmortem computerized tomographic angiography (PCTA). Despite careful dissection, however, a source of bleeding may never be identified.

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“…La epistaxis es el sangrado que ocurre en la cavidad nasal y representa una de las causas más frecuentes de consulta en el servicio de urgencias, así como la causa más frecuente de ingreso al servicio de otorrinolaringología (1). Dos tercios de la población han presentado por lo menos un episodio de epistaxis durante su vida, de los cuales el 6 % requieren atención médica (2). Además, cuenta con dos picos de presentación: el primero en pacientes jóvenes <10 años, (3) y el segundo en pacientes entre los 45-75 años (4).…”

Section: Introductionunclassified

Caracterización de la población que consulta por epistaxis al servicio de otorrinolaringología del Hospital Universitario Mayor Méderi (HUM)

Arias¹,

López²,

Vergára³

2020

Acta otorrinolaringol cir cabeza cuello

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Introducción: La epistaxis es uno de los principales motivos de consulta por urgencias en el servicio de Otorrinolaringología. La mayoría de los episodios se originan en el septo nasal anterior y su manejo tiende a ser conservador. Objetivo: Caracterizar la población que consulta por epistaxis al servicio de Otorrinolaringología del Hospital Universitario Mayor Méderi (HUM) entre marzo de 2017 y febrero de 2018. Metodología: Estudio observacional, descriptivo, de corte transversal, con recolección de datos de forma retrospectiva de pacientes que ingresan a urgencias del HUM por epistaxis, registrados en la base de datos del servicio de Otorrinolaringología. Se analizaron datos demográficos, localización del sangrado, tratamiento, comorbilidades, fármacos y cifras tensionales.

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Epistaxis and catastrophic nasal bleeding

Cited by 5 publications

References 32 publications

Potential of Antioxidant Protection in Patients With Epistaxis

Potential of Antioxidant Protection in Patients With Epistaxis

Lethal Epistaxis

Caracterización de la población que consulta por epistaxis al servicio de otorrinolaringología del Hospital Universitario Mayor Méderi (HUM)

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