Epiretinal Membrane: Prevalence and Risk Factors from the Korea National Health and Nutrition Examination Survey, 2008 through 2012

Kim, Jong Min; Lee, Hoyoung; Shin, Jae Pil; Ahn, Jeeyun; Yoo, Je Moon; Song, Su Jeong; Kim, Sang Jin; Kang, Se Woong

doi:10.3341/kjo.2016.0098

Cited by 28 publications

(36 citation statements)

References 27 publications

(51 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our cohort, although definite ERMs according to retinal photographs were statistically more frequent in men than in women (p = 0.009), the three ERM stages graded according to the SD-OCT images were similarly distributed between the two sexes (p = 0.75, p = 0.50 and p = 0.17 for stages 1, 2 and 3, respectively), which is in line with the findings in most of the above cited studies. Pseudophakia has constantly been associated with a higher ERM prevalence (Appiah & Hirose 1988;Klein et al 1994;Mitchell et al 1997;Fraserbell et al 2003;Fraser-Bell et al 2004;McCarty et al 2005;You et al 2008;Ng et al 2011;Cheung et al 2017;Kim et al 2017). Such a finding can result from two nonexclusive factors.…”

Section: Characteristicsmentioning

confidence: 99%

Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD‐OCT: the Alienor Study

Delyfer

Legout

Goff

et al. 2020

Acta Ophthalmologica

View full text Add to dashboard Cite

To analyse and compare the prevalence of epiretinal membranes (ERMs) obtained using either standard retinal colour images or spectral-domain optical coherence tomography (SD-OCT) in a population-based setting of French elderly subjects. Methods: Six hundred twenty-four subjects of the Alienor cohort aged 75 years or older underwent both colour fundus imaging and SD-OCT examinations. The ERMs were graded from retinal images and SD-OCT macular scans in a masked fashion. On SD-OCT images, the early ERMs, mature contractile ERMs without foveal modifications and mature contractile ERMs with foveal alterations were distinguished. Results: 610 (97.8%) subjects had gradable SD-OCT examinations, and 511 (81.9%) had gradable fundus images in at least one eye. According to colour photographs, 11.6% of participants had definite ERMs. From SD-OCT images, 52.8% of the subjects had early ERMs, 7.4% had mature ERMs without foveal involvement, and 9.7% had mature ERMs with foveal alterations. Regardless of the imaging method used, the ERMs were more often observed in pseudophakic eyes than in phakic eyes. Comparison of ERM assessment using fundus photographs versus SD-OCT images demonstrated that the specificity of retinal colour images was good (>89.3%), whereas the sensitivity remained low even though it increased with ERM severity on SD-OCT images. Conclusions: Spectral-domain optical coherence tomography (SD-OCT) examinations have high feasibility in this elderly population and are much more sensitive than standard colour images for ERM assessments, especially in the early stages of the disease. Our results further highlight the need to use SD-OCT instead of colour retinal photographs for the classification of ERMs in epidemiological studies.

show abstract

Section: Characteristicsmentioning

confidence: 99%

Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD‐OCT: the Alienor Study

Delyfer

Legout

Goff

et al. 2020

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…New technologies, such as spectraldomain optical coherence tomography (SD-OCT), allow to detect pathologies of the vitreo-macular interface with high sensitivity and specificity and to differentiate different subtypes (Wilkins et al 1996;Mori et al 2004;Kawasaki et al 2009;Hwang et al 2012;Konidaris et al 2015;Stevenson et al 2016). Previous studies using ophthalmoscopy or fundus photography in general showed a lower prevalence of epiretinal membranes (ERMs) (Mitchell et al 1997;McCarty et al 2005;You et al 2008;Duan et al 2009;Aung et al 2013;Kim et al 2017) and of other pathologies of the vitreomacular interface. In addition, since the introduction of the OCT technology, specific classification of vitreo-macular adhesion (VMA) into a focal and a broad type has been introduced (Duker et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Characteristics and pathologies of the vitreo‐macular interface—results from the Gutenberg Health Study

Schuster

Kluck

Korb

et al. 2019

Acta Ophthalmologica

View full text Add to dashboard Cite

Purpose: We aimed to determine the prevalence of characteristics and pathologies of the vitreo-macular interface within the general population. Methods: The Gutenberg Health Study is a population-based study in Germany, including an ophthalmological examination with refraction, biometry and optical coherence tomography (OCT) imaging. Characteristics of the vitreo-macular interface were graded on volume scans including visibility of an epiretinal membrane, full-thickness macular hole, lamellar hole and pseudohole. Overall and age-specific prevalences including 95% confidence intervals [95%-CI] were calculated. Association analyses were conducted to determine systemic and ocular factors that are associated with epiretinal membranes (the most common pathology) using multivariable logistic regression. Results: A total of 1890 people aged 40-80 years were included in the study. Of these, 4.7% (95%-CI: 3.8%-5.8%) had an epiretinal membrane in at least one eye, 0.1% a full-thickness macular hole, 0.6% a lamellar hole and 0.6% a pseudohole. The presence of an epiretinal membrane was associated with higher age, myopic refractive error and prior retinal laser therapy, but not with gender, body height, body weight, smoking, prior cataract surgery or intraocular pressure. Conclusions: Epiretinal membranes are more frequent in older and myopic subjects and in those with prior retinal laser therapy.

show abstract

“…The prevalence of ERM in the current study was lower than in previous population-based studies using SD-OCT. In the Beaver Dam Eye Study (BDES) [ 7 ], which was conducted in the USA population (mean age 74.1 years, both phakic and pseudophakic), the prevalence of ERM was 34.1% of the enrolled eyes. The Alienor study [ 8 ], which was conducted in the French population (mean age 79.4 years, both phakic and pseudophakic), the prevalence was 69.9% of the enrolled eyes.…”

Section: Discussionmentioning

confidence: 99%

“…Although ERM is a highly prevalent disease [5,6], the pathophysiology of ERM, especially primary ERM, is not yet fully understood. Known demographic risk factors for the development of primary ERM are age and cataract surgery, which were consistently shown in many large-scale studies [7][8][9][10][11][12]. In a recent longitudinal study using SD-OCT, the development of ERM based on aging was associated with the vitreoretinal interface (VRI), such as vitreomacular or vitreopapillary adhesion at baseline [13].…”

Section: Introductionmentioning

confidence: 99%

“…Epiretinal membrane (ERM) is a condition of cellular proliferation at the inner retinal surface [ 1 , 2 ], which has various effects on the visual quality based on its location, thickness, transparency, and contractility [ 3 , 4 ]. The prevalence of ERM reportedly ranged from 1.02% in Chinese population [ 5 ] to 28.9% in multiethnic U.S. population [ 6 ] based on fundus photography, however, the prevalence significantly increased up to 69.9% in French population because the resolution of macular images markedly improved due to the introduction of spectral-domain optical coherence tomography (SD-OCT) [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of epiretinal membrane in the phakic eyes based on spectral-domain optical coherence tomography

2021

View full text Add to dashboard Cite

The prevalence of epiretinal membrane (ERM) and associated factors in the phakic eyes have not been fully elucidated yet. This cross-sectional study included 2,354 phakic eyes without retinal diseases or surgical history. Ocular parameters, such as uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent (SE), intraocular pressure (IOP), white-to-white corneal diameter (WTW), mean keratometric value (Km) of total corneal refractive power at 4-mm diameter (TCRP4), astigmatism of TCRP4, total corneal irregular astigmatism (TCIA), pupil diameter, axial length (AXL), anterior chamber depth (ACD), lens thickness (LT), and posterior vitreous detachment (PVD) were compared between ERM group and control group. Additionally, an age-matched control group was selected by individual matching and compared with the ERM group to eliminate the confounders. Multiple logistic regression analysis was performed to evaluate the factors associated with the presence of ERM. Among 2,354 eyes, 429 eyes (18.2%) had ERM based on spectral-domain optical coherence tomography. The ERM group showed higher prevalence of PVD, worse CDVA, higher astigmatism of TCRP4, higher TCIA, smaller pupil size, longer AXL, and thicker LT than control group (P < 0.001, P < 0.001, P = 0.011, P < 0.001, P = 0.023, P < 0.001, and P < 0.001, respectively). Only PVD, CDVA, SE, astigmatism of TCRP4, TCIA, and AXL maintained the significance when compared with the age-matched control group (P < 0.001, P = 0.026, P < 0.001, P = 0.001, P = 0.003, and P < 0.001, respectively). Multivariate logistic regression analysis showed that age, PVD, CDVA, and TCIA were independently associated with the presence of ERM (P < 0.001, P < 0.001, P = 0.011, and P = 0.002). The prevalence of ERM detected using SD-OCT was 18.2% in the middle aged phakic population. Eyes with TCIA, in addition to older age and PVD, were more likely to have ERM.

show abstract

Epiretinal Membrane: Prevalence and Risk Factors from the Korea National Health and Nutrition Examination Survey, 2008 through 2012

Cited by 28 publications

References 27 publications

Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD‐OCT: the Alienor Study

Prevalence of epiretinal membranes in the ageing population using retinal colour images and SD‐OCT: the Alienor Study

Characteristics and pathologies of the vitreo‐macular interface—results from the Gutenberg Health Study

Prevalence of epiretinal membrane in the phakic eyes based on spectral-domain optical coherence tomography

Contact Info

Product

Resources

About