Epikeratophakia in Children

Morgan, Keith S.; Stephenson, Gary S.; McDonald, Marguerite B.; Kaufman, Herbert E.

doi:10.1016/s0161-6420(84)34238-5

Cited by 47 publications

(5 citation statements)

References 11 publications

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“…They were mixed to a ratio of 7:1 (MAP-COX) in a plastic dish imme¬ diately before use. Following placement of the MAP-COX combination, the edges of the lenticule were tucked into the keratotAccepted for publication April 6,1988 -Intact epikeratoplasty, using mussel adhesive proteins, 14 days after surgery. Note that iris detail is equally visible across both central and peripheral cornea.…”

Section: Materials and Methods Materialsmentioning

confidence: 99%

Preliminary Evaluation of the Use of Mussel Adhesive Protein in Experimental Epikeratoplasty

Robin¹,

Picciano²,

Kusleika³

et al. 1988

Archives of Ophthalmology

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Section: Materials and Methods Materialsmentioning

confidence: 99%

Preliminary Evaluation of the Use of Mussel Adhesive Protein in Experimental Epikeratoplasty

Robin¹,

Picciano²,

Kusleika³

et al. 1988

Archives of Ophthalmology

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“…However, such large onlay grafts disrupt and overlie the host limbal stem cells that results in delayed re-epithelialisation of the graft or persistent epithelial defects that are the commonest complications of the procedure. 47,48 This in turn may lead to increased chances of infection and the ensuing complications. Javadi et al 49 have described a variation in the technique to avoid limbal stem cell damage.…”

Section: Treatmentmentioning

confidence: 99%

Keratoglobus

Wallang

Das²

2013

Eye

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Keratoglobus is a rare noninflammatory corneal thinning disorder characterised by generalised thinning and globular protrusion of the cornea. It was first described as a separate clinical entity by Verrey in 1947. Both congenital and acquired forms have been shown to occur, and may be associated with various other ocular and systemic syndromes including the connective tissue disorders. Similarities have been found with other noninflammatory thinning disorders like keratoconus that has given rise to hypotheses about the aetiopathogenesis. However, the exact genetics and pathogenesis are still unclear. Clinical presentation is characterised by progressive diminution resulting from irregular corneal topography with increased corneal fragility due to extreme thinning. Conservative and surgical management for visual rehabilitation and improved tectonic stability have been described, but remains challenging. In the absence of a definitive standard procedure for management of this disorder, various surgical procedures have been attempted in order to overcome the difficulties. This article reviews the aetiological factors, differential diagnosis, histopathology, and management options of keratoglobus.

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“…Wood (40) nota una refracción mió-pica relacionándola con la mayor curvatura de la superficie corneal anterior. Por esta razón, en una etapa anterior al uso común de lentes intraoculares asociada a la queratoplastia, se sugirió el empleo de córneas infantiles como una posible alternativa quirúrgica refractiva tanto para la corrección de la afaquia unilateral (40,41) como en casos de queratoplastia penetrante combinada simultáneamente con la extracción intracapsular de catarata (41) o para la epiqueratofaquia en cataratas congénitas y traumá-ticas (42). Koenig y cols (37) examinan cinco pacientes adultos intervenidos con córneas de donantes de 3 meses de edad o menos que muestran una miopía inducida, atribuyéndolo al elevado poder refractivo de la córnea infantil.…”

Section: B) Problemas Refractivosunclassified

Idoneidad del injerto corneal de donante neonato en la queratoplastia penetrante

Belmonte

Moral

Vallcanera

2008

Arch Soc Esp Oftalmol

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RESUMENObjetivo: El límite inferior de edad del donante corneal resulta polémico. A pesar de la mayor densidad endotelial neonatal existen problemas quirúr-gicos (anatomía corneal infantil), refractivos (tendencia a miopización) y postoperatorios (mayor inmunogenicidad). Se analizan dos casos con empleo de tejido donante de 4 meses, con resultado refractivo postoperatorio atípico en ambos y desproporcionada respuesta inmune en uno. A propósi-to de los mismos, se realiza una revisión sobre el uso de injertos de donantes pediátricos en la queratoplastia penetrante. Métodos: Se presentan dos pacientes jóvenes con queratocono intervenidos de queratoplastia penetrante con injerto donante de 4 meses y alta densidad endotelial (4.500 cel/mm 2 ). Resultados: En el postoperatorio inmediato presentaron una elevada hipermetropía (se redujo posteriormente) con escaso astigmatismo. En uno aumentó notablemente el astigmatismo tras la excisión de sutura precisando queratotomía arcuata y puntos de refuerzo, mostrando al año y medio injerto transparente, agudeza visual corregida de V=1 y densidad endotelial alta (4.300 cel/mm 2 ). El otro presentó a los 7 meses un rechazo con edema del REVISIÓN ABSTRACT Objective: The lower recommended age of the donor cornea is a controversial matter. Although newborn corneas have a high endothelial cell density, there are anatomical, refractive (myopic shift) and postoperative problems. Two cases are analyzed; one had an atypical refractive result and the other an unexpectedly severe immune response. We also review the use of pediatric donor corneas in penetrating keratoplasty. Methods: Two young patients with keratoconus, in whom a penetrating keratoplasty was done using a 4-month-old newborn corneal donor with high endothelial cell density (4.500 cell/mm 2 ) are reported. Results: In the early postoperative period, both had high hypermetropy with weak astigmatism that improved over the next few months. In one patient a marked increase in the astigmatism after removal of the continuous suture was observed. One and a half years after the penetrating keratoplasty there was V=1 corrected vision and the endothelial population was almost unchanged (4,300 cell/mm 2 ). The other patient suffered an allograft reaction with corneal oedema in the seventh postoperative month, and subsequent rupture of the continuous suture made its early removal necessary. The oedema par-

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Epikeratophakia in Children

Cited by 47 publications

References 11 publications

Preliminary Evaluation of the Use of Mussel Adhesive Protein in Experimental Epikeratoplasty

Preliminary Evaluation of the Use of Mussel Adhesive Protein in Experimental Epikeratoplasty

Keratoglobus

Idoneidad del injerto corneal de donante neonato en la queratoplastia penetrante

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