Epigenetic drug Gar1041 in combination with antiretroviral therapy transiently reduces the proviral DNA reservoir in SIVmac251‐infected macaques

Mg, Lewis; Norelli, Sandro; Chomont, N.; Fonseca, Sharon; Sgarbanti, Marco; Collins, Matt; Chirullo, Barbara; Yalley-Ogunro, Jake; Greenhouse, Jack; Palamara, A T; Garaci, Enrico; Savarino, Andrea

doi:10.1186/1758-2652-13-s3-o14

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2010

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“…Savarino observed a significant decay in proviral SIV DNA when Gar1041 was administered to macaques infected with SIVmac251 and treated with intensified ART. There was also evidence of delayed viral rebound and improved immune control of SIV replication when ART was stopped [ 33 ].…”

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confidence: 99%

Workshop report: “Towards a Cure: HIV Reservoirs and Strategies to Control Them”

Jefferys

2010

Journal of the International AIDS Society

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On 16 and 17 July 2010, immediately prior to the XVIII International AIDS Conference in Vienna, Austria, the International AIDS Society held a workshop on the important topic of moving beyond antiretroviral therapy and addressing HIV persistence. “Towards a Cure: HIV Reservoirs and Strategies to Control Them” was chaired by Nobel laureate Françoise Barré-Sinoussi and co-sponsored by the French National Agency for Research on AIDS and Viral Hepatitis, Bundesministerium für Wissenschaft und Forschung, the National Institutes of Health, Sidaction and the Treatment Action Group. This article gives an overview of the findings presented at the workshop; complete abstracts are included in this supplement to the Journal of the International AIDS Society.

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Section: Main Textmentioning

confidence: 99%

Workshop report: “Towards a Cure: HIV Reservoirs and Strategies to Control Them”

Jefferys

2010

Journal of the International AIDS Society

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Epigenetic drug Gar1041 in combination with antiretroviral therapy transiently reduces the proviral DNA reservoir in SIVmac251‐infected macaques

Abstract: 16‐17 July 2010, International AIDS Society’s Workshop “Towards a Cure”: HIV Reservoirs and Strategies to Control Them, Vienna, Austria

Cited by 1 publication

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Workshop report: “Towards a Cure: HIV Reservoirs and Strategies to Control Them”

Workshop report: “Towards a Cure: HIV Reservoirs and Strategies to Control Them”

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