Epigenetic analytical approaches in ecotoxicological aquatic research

Pham, Kim; Ho, Long; D’Incal, Claudio Peter; Cock, Andrée De; Berghe, Wim Vanden; Goethals, Peter

doi:10.1016/j.envpol.2023.121737

Cited by 1 publication

(1 citation statement)

References 185 publications

(197 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several effect-based methods and technological interventions can be used in monitoring routine and investigative endeavors to assess the ecological condition related to pollution burden [234][235][236]. Microbial biosensors (cell-free and whole-cell-based) [237][238][239] metagenomic and metatranscriptomic methods, such as high-throughput sequencing of organisms exposed to chemicals [240][241][242][243], have the potential to improve the efficacy of structure-based ecosystem analyses. These approaches can establish more explicit links between chemicals, their modes of action, and ecological functions [244].…”

Section: Bioindicator Species: Methods and Platformsmentioning

confidence: 99%

Insights in Pharmaceutical Pollution: The Prospective Role of eDNA Metabarcoding

Papaioannou,

Geladakis,

Kommata

et al. 2023

Toxics

View full text Add to dashboard Cite

Environmental pollution is a growing threat to natural ecosystems and one of the world’s most pressing concerns. The increasing worldwide use of pharmaceuticals has elevated their status as significant emerging contaminants. Pharmaceuticals enter aquatic environments through multiple pathways related to anthropogenic activity. Their high consumption, insufficient waste treatment, and the incapacity of organisms to completely metabolize them contribute to their accumulation in aquatic environments, posing a threat to all life forms. Various analytical methods have been used to quantify pharmaceuticals. Biotechnology advancements based on next-generation sequencing (NGS) techniques, like eDNA metabarcoding, have enabled the development of new methods for assessing and monitoring the ecotoxicological effects of pharmaceuticals. eDNA metabarcoding is a valuable biomonitoring tool for pharmaceutical pollution because it (a) provides an efficient method to assess and predict pollution status, (b) identifies pollution sources, (c) tracks changes in pharmaceutical pollution levels over time, (d) assesses the ecological impact of pharmaceutical pollution, (e) helps prioritize cleanup and mitigation efforts, and (f) offers insights into the diversity and composition of microbial and other bioindicator communities. This review highlights the issue of aquatic pharmaceutical pollution while emphasizing the importance of using modern NGS-based biomonitoring actions to assess its environmental effects more consistently and effectively.

show abstract