Epidural scopolamine administration in preventing nausea after epidural morphine

Moscovici, Roland; Prego, George; Schwartz, Marcela; Steinfeld, Osias

doi:10.1016/0952-8180(95)00056-n

“…• lnfusions of opioid-alone > combined opioid + local anesthetic infusions • Morphine > fentanyl • Continuous infusion > single-shot epidural injections (cumulative incidence) dexamethasone, and transdermal scopolamine) may be used to treat PONV, the majority of trials have examined these agents for the prevention and treatment of PONV associated with primarily single-shot neuraxial opioids, not continuous epidural infusions of opioids [25,26,32,33] (Box 18-2).…”

Section: Box 18-1 Incidence Of Nausea and Vomiting During Epidural Anmentioning

confidence: 99%

Complications Associated with Continuous Epidural Analgesia

Wu¹,

Richman

²

2007

Complications in Regional Anesthesia &Amp; Pain Medicine

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Drugs for preventing postoperative nausea and vomiting

Carlisle

¹

,

Stevenson²

2006

Cochrane Database of Systematic Reviews

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Either nausea or vomiting is reported to affect, at most, 80 out of 100 people after surgery. If all 100 of these people are given one of the listed drugs, about 28 would benefit and 72 would not. Nausea and vomiting are usually less common and, therefore, drugs are less useful. For 100 people, of whom 30 would vomit or feel sick after surgery if given placebo, 10 people would benefit from a drug and 90 would not. Between one to five patients out of every 100 people may experience a mild side effect, such as sedation or headache, when given an antiemetic drug. Collaborative research should focus on determining whether antiemetic drugs cause more severe, probably rare, side effects. Further comparison of the antiemetic effect of one drug versus another is not a research priority.

show abstract

Drugs for preventing postoperative nausea and vomiting

Carlisle

¹

,

Stevenson²

2017

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

Either nausea or vomiting is reported to affect, at most, 80 out of 100 people after surgery. If all 100 of these people are given one of the listed drugs, about 28 would benefit and 72 would not. Nausea and vomiting are usually less common and, therefore, drugs are less useful. For 100 people, of whom 30 would vomit or feel sick after surgery if given placebo, 10 people would benefit from a drug and 90 would not. Between one to five patients out of every 100 people may experience a mild side effect, such as sedation or headache, when given an antiemetic drug. Collaborative research should focus on determining whether antiemetic drugs cause more severe, probably rare, side effects. Further comparison of the antiemetic effect of one drug versus another is not a research priority.

show abstract

Epidural scopolamine administration in preventing nausea after epidural morphine

Cited by 11 publications

References 13 publications

Complications Associated with Continuous Epidural Analgesia

Complications Associated with Continuous Epidural Analgesia

Drugs for preventing postoperative nausea and vomiting

Drugs for preventing postoperative nausea and vomiting

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