Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System

Chan, Peter

doi:10.1007/978-1-4615-0679-9_32

Cited by 51 publications

(77 citation statements)

References 142 publications

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“…The vas deferens is a highly muscular tube and the only structure in the body with its lumen thinner than the wall 1 . This implies that any pathology in it will cause increase resistance to the flow of its content.…”

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

“…Tumor within the vas deferens is rare in literature, however there are scanty reports on the inflammation 1 . Two patterns of inflammation had been described; Vasitis nodosa and Acute vasitis 1,2 . Vasitis nodosa is the commonest retrieved from that is reported in the literature.…”

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

“…It is a benign condition that was first reported by Benjamin in 1943, who described it as a non-tuberculosis cause of vasal beading 3 . It is usually associated with a history of vasectomy and patients present with a nodular mass in the vas deferens which may not be symptomatic and they require no specific treatment 1,3,4 . Acute vasitis is less reported when compared to vasitis nodosa.…”

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

“…Pathogens causing it include Escherichia Coli and Haemophilus influenza 1 . Patients presenting with this condition usually present with a mass in the groin or scrotal spermatic cord 1,2 . We therefore report a case of acute vasitis who presented in the radiology department of a private hospital in Lagos, with a clinical diagnosis of a painful scrotal swelling A 62yr old male presented to us on account of a 4 days history of left groin pain and inguinoscrotal swelling.…”

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

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Acute Vasitis Presenting as an Inguinoscrotal Swelling: A Diagnostic Dilemma

A¹

2017

IJCC

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Abstract:Vasitis or inflammation of the vas deferens and spermatic cord has been identified as a cause of scrotal swelling and needs to be differentiated from other causes of groin swelling like epididymitis, orchitis, testicular torsion, saphenous varix, femoral and inguinal hernia. This is essential in order to prevent needless surgery in such patients. Duplex Doppler Ultrasound scanning in expert hand alone is adequate in differentiating acute vasitis from other causes of groin swelling. Computed tomography scan is also often needed to confirm the ultrasound findings. This case is therefore presented to emphasize the difficulty in diagnosing acute vasitis and differentiate it from inguinal hernia, which is the more common clinical diagnosis given in cases of groin swelling Background:Case Presentation:

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Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

Section: Background: Case Presentation: Issn 2572-102xmentioning

confidence: 99%

See 2 more Smart Citations

Acute Vasitis Presenting as an Inguinoscrotal Swelling: A Diagnostic Dilemma

A¹

2017

IJCC

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“…In addition, various inflammatory conditions (12,13), particularly those involving the epididymides, are among the prevalent etiologies of excurrent ductal obstruction. Other conditions that can lead to obstructive or, as some investigators preferred, secre- …”

Section: Obstructive Azoospermiamentioning

confidence: 99%

Azoospermia Evaluations and treatments

Chan¹

2002

J Sex Reprod Med

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Azoospermia can be caused by the obstruction of the excurrent ductal system of the male reproductive tract or by failure of spermatogenesis in the testes. Various advanced diagnostic tools are available to help clinicians determine the underlying etiologies. These include transrectal ultrasonogram, vasography and antisperm antibody assays. In addition, advanced genetic evaluations, such as karyotype analysis, Y chromosome microdeletion and cystic fibrosis transmembrane conductance regulator mutation screening are used commonly, not only to determine the etiology of azoospermia, but also to provide crucial information for counselling of couples who choose to use assisted reproductive techniques to have children. Recent advances in the management of obstructive azoospermia with microsurgical reconstruction, such as vasovasostomy and vasoepididymostomy, have significantly improved the postoperative outcomes. For patients with spermatogenic failure that requires assisted reproduction, the recent refinements in various surgical sperm retrieval techniques, including microsurgical testicular sperm extraction and epididymal sperm aspiration, have provided more optimal treatment outcomes.Key Words: Assisted reproduction; Azoospermia; Intracytoplasmic sperm injection; Male infertility; Microsurgery; Oligospermia L'azoospermie : Les évaluations et les traitements RÉSUMÉ : L'azoospermie peut être causée par l'obstruction du système canalaire excrétoire des voies reproductrices mâles ou par l'échec de la spermatogenèse des testicules. Il existe divers outils diagnostiques avancés pour aider les cliniciens à déterminer les étiologies sous-jacentes. Ces outils incluent l'échographie transrectale, la vasographie et le dosage des anticorps immobilisants. De plus, des évaluations génétiques évoluées, telles que le caryotypage, la microdélétion du chromosome Y et le dépistage de la mutation du régulateur de la conductance membranaire de la fibrose kystique, sont souvent utilisées, non seulement pour établir l'é-tiologie de l'azoospermie, mais également pour fournir de l'information essentielle en vue de conseiller les couples qui choisissent de faire appel aux techniques de reproduction assistée pour avoir des enfants. Les récents progrès dans la prise en charge de l'azoospermie obstructive par la reconstruction microchirurgicale, comme la vasovasostomie et la vasoépi-didymostomie, ont amélioré considérablement les issues postopératoires. Dans le cas des patients présentant un échec spermatogène et qui ont besoin de reproduction assistée, les raffinements récents des diverses techniques chirurgicales d'extraction du sperme, y compris l'extraction microchirurgicale du sperme testiculaire et l'aspiration du sperme épipidy-mal, assurent des issues plus optimales des traitements.

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The Contractile Wall of the Caput Epididymidis in Men Affected by Congenital or Postinflammatory Obstructive Azoospermia

Pelliccione

Cordeschi

Giuliani

et al. 2004

Journal of Andrology

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ABSTRACT:The transport and storage of spermatozoa in the epididymis depend on the contractile activity of its tubular wall. It is not known what differences exist in the contractile wall of the human epididymis in cases of obstructive azoospermia. The contractile wall in the tubules of the caput epididymidis was analyzed by light microscopy and transmission electron microscopy in 10 azoospermic men, 5 with a bilateral congenital absence of vas deferens (CBAVD) and 5 with a bilateral postinflammatory congestive obstruction of the epididymis. Five specimens from the same region of the caput epididymidis, obtained from fertile men who had undergone an orchidectomy because of testicular cancer, served as controls. No differences were observed between congenital and congestive obstructions. The contractile wall in caput tubules proximal to the obstructed level was strongly thickened when compared with controls (62.98 Ϯ 5.84 ; 80.82 Ϯ 7.72 vs 19.59 Ϯ 2.23 , respectively, for congestive and congenital obstructions vs controls; P Ͻ .0001 vs controls), and the spindle-shaped myoid cells, which formed the contractile wall in normal cases, were replaced by large smooth muscle cells (SMCs) that showed features of coexisting contractile and secretory functions. The former included crowded cytoplasmic bundles of thin myofilaments (5-6 nm in diameter) converging to a large number of dense bodies, numerous micropinocytotic vesicles of the plasma membrane, and a continuous cell basement membrane. The presence of a developed rough endoplasmic reticulum and a Golgi complex, associated with the accumulation of thick layers of pericellular basement membrane-like material and ground substance, was indicative of a secretory phenotype of SMCs. The increased mechanical forces on the epididymal wall upstream from the obstruction might eventually activate the differentiation of myoid cells into SMCs, leading to an altered physiology of the contractile wall that could have possible clinical relevance in the case of microsurgical epididymovasostomy.Key words: Congenital absence of vas deferens, human caput epididymidis, smooth muscle cell.

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Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System

Cited by 51 publications

References 142 publications

Acute Vasitis Presenting as an Inguinoscrotal Swelling: A Diagnostic Dilemma

Acute Vasitis Presenting as an Inguinoscrotal Swelling: A Diagnostic Dilemma

Azoospermia Evaluations and treatments

The Contractile Wall of the Caput Epididymidis in Men Affected by Congenital or Postinflammatory Obstructive Azoospermia

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