HighlightsEpidermoid cysts are benign tumors -IEIC-that originate in the spine or intracraneally.Intradural compose 75% of epidermoid cysts and 25% are extradural in the diploic space—IEIC.These benign lesions although they are of low incidence, are seen very rarely in intradiploic locations and above all, of significant size, may produce significant mass effect in patients, which was initially tolerated because of its slow growth, however, they may become decompensate and cause intracranial hypertension syndrome.