Epidermoid Carcinoma of the Anus and the Rectum

Squamous cell cancer of the rectum

“…Given the rarity of the disease, strong epidemiological data regarding patient demographics, risk factors, natural history and optimal treatment is lacking. However, there have been several retrospective reviews that have tried to Raiford [1] (1933) 43 F Surgery Dead at 17 mo Catell et al [2] (1943) 63 M LAR Alive at 3.5 yr Wiener et al [3] (1962) 52 F APR Dead at 1 yr Cabrera et al [4] (1967) 62 F APR NR 50 F NR Minkowitz [5] (1967) 49 F Proctocolectomy Dead at 5 mo Williams et al [6] (1979) 45 M APR Dead at 9 mo Vezeridis et al [7] [8] (1985) 60 M TAE 5FU/MC XRT-post Alive at 2 yr Pigott et al [9] (1987) 60 F APR XRT-post Alive at 13 mo Woods [10] (1987) 57 F APR Dead at 3 mo Prener et al [11] [12] (1992) 44 M 5FU/MC & XRT NR 69 F TAE 5FU/MC&XRT-post Alive at 6 mo Martinez-Gonzalez et al [13] (1996) 40 M LAR 5FU & XRT-pre Alive at 18 mo Copur et al [14] (2001) 54 M APR Chemo& XRT-post NR Frizelle et al [15] (2001) 9 cases Sotlar et al [16] (2001) 87 M LAR 5FU/MC &XRT Dead at 20 mo Gelas et al [17] [18] (2005) 75 M APR 5FU/Cis-post Alive at 14 mo Lam et al [19] (2006) 44 F LAR XRT-pre NR Theodosopoulos et al [20] (2006) 39 F APR 5FU/MC-pre/post & XRT Alive at 18 mo Pikarsky et al [21] (2006) 57 F 5FU/MC & XRT Alive at 7 yr Nahas et al [22] (2007) 58 F10/M2 Chemo/XRT-pre Alive at 2.6 yr Chemo/XRT-pre TAE Chemo/XRT-pre TAE Chemo/XRT-pre APR Chemo/XRT-pre LAR Chemo/XRT-pre APR Chemo/XRT-pre LAR Chemo/XRT-pre LAR Chemo/XRT-pre APR Chem/XRT-post TAE Chem/XRT-post Chemo-pre Kong et al [23] provide a framework for understanding this disease. Squamous cell carcinoma of the rectum appears to affect individuals between the ages of 39 to 93 years old, with a mean age of 57 years.…”

Chemo‐radiotherapy: an alternative to surgery for squamous cell carcinoma of the rectum – report of six patients and literature review

“…Thirty‐three patients of SCC of rectum have been reported in the published reports since Catell and Williams first reported a case in 1943 [1] (Table 2). Vezeredis et al.…”

“…Purpose Since 1943 [1], only 45 patients of squamous cancer of the rectum have been reported in the published reports and the largest series to date consists of 12 patients. Reports suggest that the primary treatment is surgical resection but, in the light of nonsurgical advances in the treatment of anal squamous cell carcinoma (SCC), we present a review of the literature and report six patients treated by chemoradiation therapy (CRT).…”

Primary Squamous-Cell Carcinoma of the Rectum

“…Eighteen cases of rectal SCC have been reported since Catell and Williams 26 in 1943 ( Table 2). The mean age of diagnosis (including our cases) is 55.1 (range, 34-93) years.…”