Epidemiology of Traumatic Spinal Cord Injury in Developing Countries from 2009 to 2020: A Systematic Review and Meta-Analysis

Golestani, Ali; Shobeiri, Parnian; Sadeghi‐Naini, Mohsen; Jazayeri, Seyed Behnam; Maroufi, Seyed Farzad; Ghodsi, Zahra; Ohadi, Mohammad Amin Dabbagh; Mohammadi, Esmaeil; Rahimi‐Movaghar, Vafa; Ghodsi, Seyed Mohammad

doi:10.1159/000524867

Cited by 56 publications

(35 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The complication rate of TSCI in China was estimated at 35%, and the major secondary complications were respiratory and urinary diseases. However, after comparing the results with the developing countries ( 80 ), the results showed that pressure ulcers and urinary tract infections were the most common. In the subgroup analysis, the in-hospital mortality and complication rates in the south were higher than those in the north.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis

Hong

et al. 2023

Front. Neurol.

View full text Add to dashboard Cite

BackgroundTraumatic spinal cord injury (TSCI) is a highly fatal and disabling event, and its incidence rate is increasing in China. Therefore, we collated the epidemiological factors of TSCI in different regions of China to update the earlier systematic review published in 2018.MethodWe searched four English and three Chinese electronic databases from 1978 to October 1, 2022. From the included reports, information on sample characteristics, incidence, injury characteristics, prognostic factors, and economic burden was extracted. The selection of data was based on the PRISMA statement. The quality of the included studies was assessed by the Agency for Healthcare Research and Quality (AHRQ) tool. The results of the meta-analysis were presented in the form of pooled frequency and forest plots.ResultsA total of 59 reports (60 studies) from 23 provinces were included, of which 41 were in the Chinese language. The random pooled incidence of TSCI in China was estimated to be 65.15 per million (95% CI: 47.20–83.10 per million), with a range of 6.7 to 569.7 per million. The pooled male-to-female ratio was 1.95:1. The pooled mean age of the cases at the time of injury was 45.4 years. Motor vehicle accidents (MVAs) and high falls were found to be the leading causes of TSCI. Incomplete quadriplegia and AISA/Frankel grade D were the most common types of TSCI. Cervical level injury was the most prevalent. The pooled in-hospital mortality and complication rates for TSCI in China were 3% (95% CI: 2–4%) and 35% (95% CI: 23–47%). Respiratory problems were the most common complication and the leading cause of death.ConclusionCompared with previous studies, the epidemiological data on TSCI in China has changed significantly. A need to update the data over time is essential to implement appropriate preventive measures and formulate interventions according to the characteristics of the Chinese population.

show abstract

Section: Discussionmentioning

confidence: 99%

Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis

Hong

et al. 2023

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…Among them, falls and car accidents are the main causes [2]. Recently, the trend globally for SCI is for it to affect younger people, mostly under 30 years of age [3]. The occurrence of irreversible motor and sensory impairment following SCI has implications for the whole person [4].…”

Section: Introductionmentioning

confidence: 99%

Research Progress of MicroRNAs in Spinal Cord Injury

Deng¹,

Chen²

2023

J. Integr. Neurosci.

View full text Add to dashboard Cite

Spinal cord injury is a serious and devastating condition. Recently, research into microRNAs (miRNAs) has become increasingly exhaustive and it has been determined that they are closely related to the pathophysiological processes of spinal cord injury. They participate in the regulation of the inflammatory response of spinal cord injury, the death of neuronal cells, and the repair of neural functions, which are related to the recovery of spinal cord injury. This review focuses on the relationship between miRNA and spinal cord injury, lists miRNA-324-5p, miRNA-221 and miRNA-124, which are helpful for the repair of spinal cord injury, and finally summarizes the current research progress of miRNA-based therapies, so as to provide a foundational reference for clinical and scientific researchers.

show abstract

“…A lesão traumática da medula espinhal (LTME) é a mais prevalente entre as pessoas (GOLESTANI et al, 2022;PEREIRA;DE CASTRO;BARBOSA, 2022). Nesse sentido, estima-se que nos países em desenvolvimento a incidência de LTME é de aproximadamente 22,55 milhões por ano, sendo que 80,09% dos casos ocorrem em pessoas do sexo masculino com idade inferior a 30 anos (GOLESTANI et al, 2022). O nível da LTME mais prevalente é a lesão cervical e a causa mais comum das lesões são os acidentes automobilísticos (GOLESTANI et al, 2022;PEREIRA et al, 2022).…”

Section: Introductionunclassified

“…Nesse sentido, estima-se que nos países em desenvolvimento a incidência de LTME é de aproximadamente 22,55 milhões por ano, sendo que 80,09% dos casos ocorrem em pessoas do sexo masculino com idade inferior a 30 anos (GOLESTANI et al, 2022). O nível da LTME mais prevalente é a lesão cervical e a causa mais comum das lesões são os acidentes automobilísticos (GOLESTANI et al, 2022;PEREIRA et al, 2022).…”

Section: Introductionunclassified

Métodos de avaliação da aptidão cardiorrespiratória e composição corporal de adultos com lesão medular: uma revisão sistemática

Martins¹,

Mazi²,

Leite³

et al. 2023

Braz. J. Develop.

View full text Add to dashboard Cite

Objetivo: Identificar quais são as ferramentas de avaliação utilizadas para mensurar as alterações na aptidão cardiorrespiratória (ACR) e composição corporal (CC) provocadas pelo exercício físico em adultos com lesão da medula espinhal (LME). Metodologia: Uma revisão sistemática da literatura científica produzida de janeiro/2017 a abril/2022 nas bases de dados PubMed, Embase, Cochrane Library, Lilacs e Scielo. Resultados: Foram incluídos seis ensaios clínicos randomizados e controlados. A ergoespirometria em cicloergômetro de membros superiores, as medidas antropométricas e a absorciometria de raios-x de dupla energia (DEXA) foram as ferramentas utilizadas para quantificar as adaptações na ACR e CC, respectivamente. Além disso, os estudos observaram aumento da ACR após o exercício físico, no entanto, não foram encontradas mudanças na CC. Conclusão: A ergoespirometria em cicloergômetro de membro superior, a DEXA e as medidas antropométricas parecem ser as principais ferramentas utilizadas na literatura para quantificar as mudanças na ACR e CC em adultos com LME, após o exercício físico. Por fim, o exercício físico pode ser uma intervenção não farmacológica capaz de melhorar a ACR de adultos com LME crônica.

show abstract

Epidemiology of Traumatic Spinal Cord Injury in Developing Countries from 2009 to 2020: A Systematic Review and Meta-Analysis

Cited by 56 publications

References 66 publications

Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis

Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis

Research Progress of MicroRNAs in Spinal Cord Injury

Métodos de avaliação da aptidão cardiorrespiratória e composição corporal de adultos com lesão medular: uma revisão sistemática

Contact Info

Product

Resources

About