Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis

Abstract

BackgroundTraumatic spinal cord injury (TSCI) is a highly fatal and disabling event, and its incidence rate is increasing in China. Therefore, we collated the epidemiological factors of TSCI in different regions of China to update the earlier systematic review published in 2018.MethodWe searched four English and three Chinese electronic databases from 1978 to October 1, 2022. From the included reports, information on sample characteristics, incidence, injury characteristics, prognostic factors, and economic burden was extracted. The selection of data was based on the PRISMA statement. The quality of the included studies was assessed by the Agency for Healthcare Research and Quality (AHRQ) tool. The results of the meta-analysis were presented in the form of pooled frequency and forest plots.ResultsA total of 59 reports (60 studies) from 23 provinces were included, of which 41 were in the Chinese language. The random pooled incidence of TSCI in China was estimated to be 65.15 per million (95% CI: 47.20–83.10 per million), with a range of 6.7 to 569.7 per million. The pooled male-to-female ratio was 1.95:1. The pooled mean age of the cases at the time of injury was 45.4 years. Motor vehicle accidents (MVAs) and high falls were found to be the leading causes of TSCI. Incomplete quadriplegia and AISA/Frankel grade D were the most common types of TSCI. Cervical level injury was the most prevalent. The pooled in-hospital mortality and complication rates for TSCI in China were 3% (95% CI: 2–4%) and 35% (95% CI: 23–47%). Respiratory problems were the most common complication and the leading cause of death.ConclusionCompared with previous studies, the epidemiological data on TSCI in China has changed significantly. A need to update the data over time is essential to implement appropriate preventive measures and formulate interventions according to the characteristics of the Chinese population.

A Systematic Review: Exercise Based Approaches to Activate Central Pattern Generator in Spinal Cord Injury Survivors

“…Exercise also acts as neuroprotective therapy. Findings of the studies have been justified with the fact that exercise-based approach cannot induce neural firing however it is believed to modulate the increased rate of spontaneous neuronal firing specific to activate the CPG for Locomotion thus justifying the synergistic effects with the better functional outcome at the end [24][25][26][27]. However, extensive variability was observed in terms of intervention dosage, frequency and variety of exercises such as intensity of activity, duration of activity, repetition of activity, number and frequency of sessions [28,29].…”

The Impact of COVID-19 on Rehabilitation Outcomes of Traumatic and Non-Traumatic Spinal 1 Cord Injury Patients: A Comparative Study Across Different Time Periods

“…A systematic review of 17 studies undertaken in China revealed that the epidemiological features of SCI differed signi cantly across various regions of the country [15,16]. This implies that tailored preventive measures need to be implemented based on the speci c characteristics of each region.…”

Incidence of Acute Complications Associated with Spinal Cord Injury (SCI): A Study of the Ayub Teaching Hospital, Abbottabad

“…The most prevalent consequence and major cause of mortality was respiratory issues. 19 Spinal cord injury (SCI) is a frequent disorder, with one million new cases reported each year and 27 million individuals living with SCI-related symptoms. SCIs impose a cost on healthcare systems and economies in the form of lost productivity and expensive healthcare expenses.…”