Epidemiology of Ocular Herpes Simplex

Liesegang, Thomas J.

doi:10.1001/archopht.1989.01070020221029

Cited by 306 publications

(179 citation statements)

References 21 publications

(2 reference statements)

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“…Herpes simplex virus is a cosmopolite virus with significative prevalence of ophthalmic infection in both developed and underdeveloped countries [1]. This infection may be asymptomatic or be followed by conjunctivitis, blepharitis and keratitis that may result in corneal scarring and neovascularization with corresponding reduction of the vision [2,3].…”

supporting

confidence: 45%

“…This infection may be asymptomatic or be followed by conjunctivitis, blepharitis and keratitis that may result in corneal scarring and neovascularization with corresponding reduction of the vision [2,3]. It is the most prevalent cause of corneal opacification, blindness and secondary glaucoma in humans worldwide [1]. Approximately 90% of HSV ophthalmic infection are caused by the virus type 1 (HSV-1) and the remainder by the type 2 (HSV-2) [4][5][6].…”

supporting

confidence: 42%

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Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation

Pereira¹,

Ma²,

Lv³

et al. 2001

Braz J Infect Dis

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Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs.

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supporting

confidence: 45%

supporting

confidence: 42%

Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation

Pereira¹,

Ma²,

Lv³

et al. 2001

Braz J Infect Dis

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“…Stromal disease accounts for approximately 2 % of initial episodes of ocular HSV disease, but it accounts for 20-48 % of recurrent ocular HSV disease [26][27][28]. Two manifestations of stromal disease from HSV involve the stroma primarily.…”

Section: Hsv Stromal Keratitismentioning

confidence: 40%

Current Concepts in the Management of Herpes Simplex Anterior Segment Eye Disease

Reddy

Rapuano

2013

Curr Ophthalmol Rep

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Herpes simplex virus-1 (HSV-1) infects the majority of the world's population during their lifetime. The prevalence of HSV primarily depends on geographic location, socioeconomic status, and age. HSV ocular disease rarely manifests as primary disease and most commonly as a recurrent disease. Recurrent HSV affects all the anterior segment structures in various clinical forms. In the cornea, HSV manifests as epithelial, stromal and endothelial disease. Depending on the structure involved, signs, symptoms and management options differ. Early diagnosis and prompt and appropriate management can lead to early resolution of the disease and maintenance of anatomic and functional integrity of ocular structures.

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“…It can present in a broad range of manifestations from primary blepharoconjuntivitis to recurrent forms of keratitis and even intraocular involvement as that seen in retinitis and uveitis (46,47) . Although there is no evidence of HVS direct infection in the lacrimal gland it has been demonstrated that corneal sensation and tear production are significant lower in patients with ocular herpetic disease (48,49) .…”

Section: Hsv and Ocular Surfacementioning

confidence: 41%

Dry eye disease caused by viral infection: review

Alves¹,

Angerami²,

Rocha³

2013

Arq. Bras. Oftalmol.

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Dry eye disease and ocular surface disorders may be caused or worsened by viral agents. There are several known and suspected virus associated to ocular surface diseases. The possible pathogenic mechanisms for virus-related dry eye disease are presented herein. This review serves to reinforce the importance of ophthalmologists as one of the healthcare professional able to diagnose a potentially large number of infected patients with high prevalent viral agents. Keywords

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Epidemiology of Ocular Herpes Simplex

Cited by 306 publications

References 21 publications

Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation

Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation

Current Concepts in the Management of Herpes Simplex Anterior Segment Eye Disease

Dry eye disease caused by viral infection: review

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