Epidemiology of middle ear and mastoid cholesteatomas: study of 1146 cases

Abstract

Mi ddle ear cholesteatoma is an important and relatively common disorder which may have serious consequences. Aim:The purpose was to conduct a retrospective study of the statistics of 1,146 middle ear surgical procedures for middle ear cholesteatoma in adults and children of low income living in distant areas from our city. Methods:From 1962 to 1988 there were 1,146 surgeries for unilateral or bilateral cholesteatomas in children and adults, which were reviewed for the following criteria: total number of surgeries, sex, onset of the first symptoms, duration of the disease, the site of perforation, the cholesteatoma site, changes in the ossicular chain, the contralateral ear, bilateral cholesteatomas, the site of residual cholesteatoma, and complications. Results:Results are shown graphically on a pie chart. Conclusion:The etiology of cholesteatomas remains unknown. Epidemiological and statistical data, surgical reports, and conclusions of experimental studies are welcome, as they may provide support for clarifying the pathogenesis of cholesteatoma. Our results were compared with internationally published papers. We found no published papers on the epidemiology of cholesteatoma in the Brazilian literature. Braz J Otorhinolaryngol. 2011;77(3):341-47. ORIGINAL ARTICLE BJORL

Change in Detection Rate of Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa and Their Antibiotic Sensitivities in Patients with Chronic Suppurative Otitis Media

“…The reason for this is that androgens in males and estrogens in females modulate host immunity, and these sex steroids affect disease resistance genes and behaviors [14] . Although one epidemiologic study reported a slightly higher male predominance in patients with cholesteatoma irrespective of age [15] , we found that the incidence of CSOM was slightly lower in males than in females, suggesting that gender predominance is associated with gender differences in immune responses. This hypothesis, however, requires further verification, such as the measurement of serum immunoglobulin concentrations in males and females with cholesteatoma.…”

Clinico social profile of patients of attico-antral disease in middle ear cleft attending tertiary care center of North India

“…It also highlights the reason that patients often attribute little importance to otological symptoms except when there is pain, dizziness, or bleeding; Cholesteatomas may be well known to ENT specialists, but is less familiar to paediatricians and general practitioners. 9 The predominance of unilateral disease in patients of this study cannot be ascribed to any specific reason and might be an incidental finding. However a Clinico-pathological study of CSOM (both safe and unsafe types) reported bilateral disease in 58% patients.…”

A comparative study on the nasal endoscopic findings in patients with chronic otitis media

“…According to Sade et al, chronic otitis media (COM) affects 0.5 to 30% of individuals in any community and over 20 million people suffer from this condition worldwide. 1,2 The disease often begins in childhood as a spontaneous tympanic membrane perforation following an acute infection of the middle ear, known as acute otitis media (AOM), or as a sequel of less severe forms of otitis media (E.g. secretory OM).…”