Epidemiology of iliopsoas haematoma in patients with haemophilia

Abstract

Aim: Iliopsoas Haemorrhage (IPH) is a well-recognized complication of haemophilia. The aim of this paper is to show the current epidemiology of IPH in patients with haemophilia (PWH) treated at Argentinean Haemophilia Foundation, and observe the evolution of the treatment of the disease over the years. Patients and methods: The 1995 series included 109 PWH with 223 episodes of IPH. Eighty-six (80.4%) patients had Haemophilia A and twenty-one (19.6%) had Haemophilia B, mean age was 18 years old. The 2008-2013 series included thirty-six PWH with sixty-five episodes of IPH. Twenty-nine (80.6%) patients with Haemophilia A and seven patients (19.4%) with Haemophilia B, all were severe. Seven patients with inhibitors and Haemophilia A, mean age was 22.1 years old. Results: We found statistically significant differences between relation to the age (p: .003). In 2008-2013 series all patients had severe Haemophilia (100%). Only eleven (30.6%) patients presented previous IPH. In the pre 1995 series, twelve (12.1%) were mild, forty (40.4%) moderate and forty-seven (47.5%) severe. Forty-nine (45.8%) patients presented previous IPH. We only found statistically significant differences when comparing the degree of the disease between series (p: .001). Conclusion: The usage of clotting factor concentrates, prophylactic therapy protocols by patients have contributed to increase the age of appearance IPH and decreased the prevalence rate of this pathology.