Epidemiology of HPV in Head and Neck Cancer: Variant Strains, Discrete Protein Function

Ragin, Camille; Liu, Jeffrey

doi:10.1007/978-1-4614-8815-6_3

Cited by 2 publications

(8 citation statements)

References 171 publications

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“…HPV can infect cutaneous or mucosal sites; cutaneous types include HPV 2, 3, 10, and 57 causing common warts and flat warts [31]. Mucosal HPV are categorized into high-risk HPV and low-risk HPV groups, according to their ability to transform epithelial cells [3]. The WHO defines 12 HPV types as being high-risk cancer causing types, and further eight types are regarded as possible cancer causing [31] [3,30,31].…”

Section: Human Papillomavirusmentioning

confidence: 99%

“…Mucosal HPV are categorized into high-risk HPV and low-risk HPV groups, according to their ability to transform epithelial cells [3]. The WHO defines 12 HPV types as being high-risk cancer causing types, and further eight types are regarded as possible cancer causing [31] [3,30,31]. Benign lesions in the oral cavity are common, and most often involve HPV 6 and 11.…”

Section: Human Papillomavirusmentioning

confidence: 99%

“…Benign lesions in the oral cavity are common, and most often involve HPV 6 and 11. These HPV genotypes are also often associated with uncommon benign conditions in the larynx such as laryngeal papillomatosis and laryngeal polyps [3]. Epidemiological studies have shown that HPVs are present in humans almost globally, however, infection with high risk strains can lead to development of cancer only in a small fraction of cases [32].…”

Section: Human Papillomavirusmentioning

confidence: 99%

“…HPV associated malignancies of the head and neck vary by site and arise mainly in oropharyngeal sites [3,23], such as tonsils, base of tongue, and other oropharynx, while other oral sites, such as the ventrolateral tongue, gingivae, cheek, palate, and floor of mouth shows less HPV association and are mainly attributed to tobacco and alcohol use [3,47]. The incidence of HPV-positive OSCC has increased worldwide [38,48,49].…”

Section: Hpv-positive Head and Neck Cancersmentioning

confidence: 99%

“…The incidence of HPV-positive OSCC has increased worldwide [38,48,49]. In the oropharynx, tonsillar tumours followed by base of tongue cancers have the highest HPV prevalence rate [3,12,22,50,51], and these two carcinomas account for 90% of all oral squamous cell carcinomas [3]. Increased incidence of oropharyngeal cancers has been observed in developed countries, where HPV has consistently been detected in these cancers [3,22].…”

Section: Hpv-positive Head and Neck Cancersmentioning

confidence: 99%

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Human Papillomavirus Associated Cancers of the Head and Neck: An Australian Perspective

Aldalwg

Brestovac

2017

Head and Neck Pathol

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Human papillomavirus (HPV) associated head and neck squamous cell carcinomas (HNSCCs), have become a serious global health problem. Despite decreases in HPV-negative HNSCCs, the prevalence of HPV-positive HNSCCs has significantly increased. HPV-positive cancers are associated with superior survival outcomes when compared to HPV-negative cancers, which appears likely to be associated with differences in the molecular pathogenesis of the two diseases. While therapies are still problematic, the current HPV vaccine programs hold a promise for the primary prevention of HPV-related HNSCCs and since Australia was the first to introduce a nationwide HPV vaccine program, it is in a unique position to observe the effects of the vaccine on HNSCCs. This review discusses the epidemiological trends associated with HPV in HNSCC, with reference to the differences between HPV-positive and HPV-negative HNSCCs and the prevention potential of HPV vaccines.

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Section: Human Papillomavirusmentioning

confidence: 99%

Section: Human Papillomavirusmentioning

confidence: 99%

Section: Human Papillomavirusmentioning

confidence: 99%

Section: Hpv-positive Head and Neck Cancersmentioning

confidence: 99%

Section: Hpv-positive Head and Neck Cancersmentioning

confidence: 99%

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Human Papillomavirus Associated Cancers of the Head and Neck: An Australian Perspective

Aldalwg

Brestovac

2017

Head and Neck Pathol

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Factors Associated with Attitudes towards Preventing Head and Neck Cancer through HPV Vaccination in Poland: A Nationwide Cross-Sectional Survey in 2021

2022

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Human papillomavirus (HPV) infection is a risk factor for head and neck cancers (HNC). HPV-related head and neck cancers are preventable through vaccination. This study aimed to assess the attitudes towards HPV vaccination among adults in Poland, with particular emphasis on preventing HPV-related HNC, as well as identifying factors associated with a willingness to vaccinate children against HPV. This cross-sectional survey was carried out in November 2021 on a nationwide, representative sample of 1082 adults in Poland. The computer-assisted web interview (CAWI) technique was used. Only 42.5% of respondents were aware that HPV infection is a sexually transmitted disease. Less than one fourth of respondents (23.8%) indicated vaccination as an HPV infection prevention method and 51.9% of respondents correctly indicated HPV vaccine-eligible populations. Only 48.1% of respondents declared positive attitudes towards HPV vaccinations and declared that they would vaccinate their child against HPV. Males (OR: 1.43, 95% CI: 1.11–1.85; p < 0.01), respondents who did not have children (OR: 1.50, 95% CI: 1.04–2.14; p < 0.05), as well as those who had received a higher education (OR: 1.43, 95% CI: 1.11–1.85; p < 0.01), had greater odds of indicating positive attitudes towards HPV vaccinations. This study revealed a low level of public awareness of HPV vaccination as a cancer prevention method in Poland.

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Epidemiology of HPV in Head and Neck Cancer: Variant Strains, Discrete Protein Function

Cited by 2 publications

References 171 publications

Human Papillomavirus Associated Cancers of the Head and Neck: An Australian Perspective

Human Papillomavirus Associated Cancers of the Head and Neck: An Australian Perspective

Factors Associated with Attitudes towards Preventing Head and Neck Cancer through HPV Vaccination in Poland: A Nationwide Cross-Sectional Survey in 2021

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