Epidemiology of brain tumors

Davis, Faith; McCarthy, Bridget J.

doi:10.1201/b13439-3

Cited by 17 publications

(18 citation statements)

References 91 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[17][18][19][20][21][22]49 The prevalence of established risk factors (i.e., therapeutic radiation, certain inherited genes [17][18][19][20][21][22]49 ) in the general population is rare; therefore, these factors are of limited public health relevance to explain the majority of brain cancers or suggest preventive measures. 21,22 However, it has been suggested that moderate risks cannot be excluded for most occupational and environmental exposures.…”

Section: Discussionmentioning

confidence: 99%

Brain cancer mortality and potential occupational exposure to lead: Findings from the National Longitudinal Mortality Study, 1979–1989

Wijngaarden

Dosemeci

2006

Intl Journal of Cancer

View full text Add to dashboard Cite

We evaluated the association between potential occupational lead exposure and the risk of brain cancer mortality in the National Longitudinal Mortality Study (NLMS), which is a prospective census-based cohort study of mortality among the noninstitutionalized United States population (1979)(1980)(1981)(1982)(1983)(1984)(1985)(1986)(1987)(1988)(1989). The present study was limited to individuals for whom occupation and industry were available (n 5 317,968). Estimates of probability and intensity of lead exposure were assigned using a job-exposure matrix (JEM). Risk estimates for the impact of lead on brain cancer mortality were computed using standardized mortality ratio (SMR) and proportional hazards and Poisson regression techniques, adjusting for the effects of age, gender and several other covariates. Brain cancer mortality rates were greater among individuals in jobs potentially involving lead exposure as compared to those unexposed (age-and gender-adjusted hazard ratio (HR) 5 1.5; 95% confidence interval (CI) 5 0.9-2.3) with indications of an exposure-response trend (probability: low HR 5 0.7 (95% CI 5 0.2-2.2), medium HR 5 1.4 (95% CI 5 0.8-2.5), high HR 5 2.2 (95% CI 5 1.2-4.0); intensity: low HR 5 1.2 (95% CI 5 0.7-2.1), medium/high HR 5 1.9 (95% CI 5 1.0-3.4)). Brain cancer risk was greatest among individuals with the highest levels of probability and intensity (HR 5 2.3; 95% CI 5 1.3-4.2). These findings provide further support for an association between occupational lead exposure and brain cancer mortality, but need to be interpreted cautiously due to the consideration of brain cancer as one disease entity and the absence of biological measures of lead exposure. ' 2006 Wiley-Liss, Inc.

show abstract

Section: Discussionmentioning

confidence: 99%

Brain cancer mortality and potential occupational exposure to lead: Findings from the National Longitudinal Mortality Study, 1979–1989

Wijngaarden

Dosemeci

2006

Intl Journal of Cancer

View full text Add to dashboard Cite

show abstract

“…The duration of these symptoms ranges from 2 days to 3 months before presenting to us. These facts were coinciding with the literature review concerning epidemiology and clinical picture [1][2][3][4].…”

Section: Discussionmentioning

confidence: 99%

“…Over two thirds of all brain tumors in children older than 1 year are in the posterior fossa. Common tumors are: pilocytic astrocytomas, ependymomas, medulloblastomas, as well as, brain stem gliomas [1,2].…”

Section: Introductionmentioning

confidence: 99%

Telovelar Approach for Midline Posterior Fossa Tumors in Paediatrics: 25 Cases Experience

Refaat¹,

Elrefaee²,

Elhalaby³

2016

J Neurol Disord

View full text Add to dashboard Cite

Background: The classic transvermian route for excision of fourth ventricular tumors could be associated with postoperative cerebellar mutism. The Telovelar approach leads to the fourth ventricle via the cerebellomedullary fissure, avoiding retraction on the dentate nuclei and vermian incisions, hence lowering the incidence of cerebellar mutism. Objective: The aim of this study is to evaluate the Telovelar approach for excision of fourth ventricular tumors.

show abstract

“…The prognosis is usually poor 2 due to diffi culties in surgical technique, the malignant histology most of these tumors and the impossibility of treating with radiotherapy 3,4 . The rate of survival is low, around 20 to 40% 4,5 ; however, after 1980, some institutions have obtained better rates of prognosis, reporting 56% of survival at 5 years and normal neurological development after treatment in 50% of the patients [6][7][8] . In small infants the most common histological types are ependymoma, medulloblastoma, choroid plexus papilloma, astrocytoma and teratoma.…”

Section: Resumo -Objetivo E Métodomentioning

confidence: 99%

Brain tumors in the first three years of life: a review of twenty cases

Espíndola

Matushita

Pimenta

et al. 2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-Objective and Method: To review the clinical and neuropathological findings as well as the type of therapy and outcome in 20 infants under 3 years-old with central nervous system (CNS) tumor. They were treated at the Department of Neurology, "Hospital das Clínicas" University of São Paulo Medical School, from January 1997 to May 2001. Results: Astrocytoma was the most common histological type (n=7), followed by ependymoma (n=3), medulloblastoma (n=2), craniopharyngioma (n=2) and desmoplastic ganglioglioma (n=2). The location of the tumor was predominantly supratentorial. Mean follow-up time was 20.2 months with recurrence in 7 cases. For each type of tumor we have emphasized the treatment currently recommended. Conclusion: Although follow-up time is not sufficient for analyzing survival, a trend of improvement in prognosis was noted, compared to another series of cases from our Institution that had been evaluated before 1990.KEY WORDS: brain tumors, children, central nervous system tumors, neuro-oncology treatment. Tumores do sistema nervoso central nos primeiros três anos de vida: revisão de vinte casosRESUMO -Objetivo e Método: Avaliar os aspectos clínicos e histopatológicos, o tipo de tratamento e a evolução de 20 crianças menores de três anos de idade, com o diagnóstico de tumor de sistema nervoso central, que foram tratadas em nossa Instituição no período de janeiro de 1997 a maio de 2001. Resultados: O astrocitoma foi o tumor mais comum (n=7), seguido pelo ependimoma (n=3), meduloblastoma (n=2), craniofaringioma (n=2) e ganglioglioma desmoplásico infantil (n=2). A localização do tumor foi predominantemente supratentorial. A média de seguimento foi 20,2 meses e houve recidiva em sete casos. Para cada tipo de tumor enfatizamos o tipo de tratamento recomendado na atualidade. Conclusão: Embora o tempo de seguimento não seja suficiente, ainda, para analisar a sobrevida, foi notada nítida tendência a melhor prognóstico em comparação com a casuística proviniente de nossa Instituição que analisou casos abordados antes da década de 90. SP -Brasil. E-mail: adrianaespindola@uol.com.br Nearly 8 to 20% of central nervous system (CNS) tumors occur in children under three years of age 1 . The prognosis is usually poor 2 due to diffi culties in surgical technique, the malignant histology most of these tumors and the impossibility of treating with radiotherapy 3,4 . The rate of survival is low, around 20 to 40% 4,5 ; however, after 1980, some institutions have obtained better rates of prognosis, reporting 56% of survival at 5 years and normal neurological development after treatment in 50% of the patients 6-8 . In small infants the most common histological types are ependymoma, medulloblastoma, choroid plexus papilloma, astrocytoma and teratoma. Supratentorial tumors are almost twice as frequent, particularly in the fi rst year of life 9,10 . PALAVRAS-CHAVE Dra. Adriana Ávila de Espíndola -Avenida Dr. Enéas de Carvalho Aguiar 255 / 5º andar / sala 5031 -05403-000 São PauloClinical signs and symptoms are usua...

show abstract

Epidemiology of brain tumors

Cited by 17 publications

References 91 publications

Brain cancer mortality and potential occupational exposure to lead: Findings from the National Longitudinal Mortality Study, 1979–1989

Brain cancer mortality and potential occupational exposure to lead: Findings from the National Longitudinal Mortality Study, 1979–1989

Telovelar Approach for Midline Posterior Fossa Tumors in Paediatrics: 25 Cases Experience

Brain tumors in the first three years of life: a review of twenty cases

Contact Info

Product

Resources

About