Epidemiology, Microbiology and Antibiotic Sensitivity of Odontogenic Space Infections in Central India

Shakya, Neelam; Sharma, Deepak; Newaskar, Vilas; Agrawal, Deepak; Shrivastava, Sanket; Yadav, Rashi

doi:10.1007/s12663-017-1014-y

Cited by 39 publications

(51 citation statements)

References 30 publications

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“…However, Streptococcus in particular is very frequently detected in pure culture-based detection methods due to their easy cultivation. In contrast, cultivation of anaerobic bacteria is much more delicate, resulting in less frequent detection [ 24 , 30 , 57 , 59 , 60 , 61 , 62 ]. It can therefore be assumed that the culture-based detection of Streptococcus in odontogenic abscesses, as well as the antibiogram produced by this, may be attributed greater importance than is actually the case.…”

Section: Discussionmentioning

confidence: 99%

Microbiome of Odontogenic Abscesses

et al. 2021

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Severe odontogenic abscesses are regularly caused by bacteria of the physiological oral microbiome. However, the culture of these bacteria is often prone to errors and sometimes does not result in any bacterial growth. Furthermore, various authors found completely different bacterial spectra in odontogenic abscesses. Experimental 16S rRNA gene next-generation sequencing analysis was used to identify the microbiome of the saliva and the pus in patients with a severe odontogenic infection. The microbiome of the saliva and the pus was determined for 50 patients with a severe odontogenic abscess. Perimandibular and submandibular abscesses were the most commonly observed diseases at 15 (30%) patients each. Polymicrobial infections were observed in 48 (96%) cases, while the picture of a mono-infection only occurred twice (4%). On average, 31.44 (±12.09) bacterial genera were detected in the pus and 41.32 (±9.00) in the saliva. In most cases, a predominantly anaerobic bacterial spectrum was found in the pus, while saliva showed a similar oral microbiome to healthy individuals. In the majority of cases, odontogenic infections are polymicrobial. Our results indicate that these are mainly caused by anaerobic bacterial strains and that aerobic and facultative anaerobe bacteria seem to play a more minor role than previously described by other authors. The 16S rRNA gene analysis detects significantly more bacteria than conventional methods and molecular methods should therefore become a part of routine diagnostics in medical microbiology.

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Section: Discussionmentioning

confidence: 99%

Microbiome of Odontogenic Abscesses

et al. 2021

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“…The study which was done by Neelam Shkya et al in 2018 represented that, the most commonly involved age group was 21-30 years (29%) followed by 31-40 years (28%) [11]. In another study by Manu Wilfred et al in 2019, the mean age of patients was 38 (range 1-67years).…”

Section: Agementioning

confidence: 97%

“…The activity of ciprofloxacin was good against aerobes, and the only organism that exhibited considerable resistance against ciprofloxacin was S. aureus (12.5%). The inactivity of metronidazole in aerobic isolates is a known fact [11]. In another study by Manu Wilfred et al in 2019, the most common isolate microorganism, enterococci were sensitive to amoxicillin, vancomycin, linezolid, teicoplanin and cefazolin.…”

Section: Antibioticsmentioning

confidence: 98%

“…No anaerobe could be isolated from any of the specimen [24]. The study which was done by Neelam Shkya et al in 2018 represented that, streptococcus species was the most frequent, and viridians streptococci was the predominant isolated organism (n = 48) followed by Staphylococcus aureus organism (n = 20) and Enterococcus feacalis (n = 8) [11]. In a study by Manu Wilfred et al in 2017, the most common isolate in our study was enterococcus in 15 cases (37.5%), followed by staphylococcus aureus in 13 cases (32.8%).…”

Section: Microbiologymentioning

confidence: 99%

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Evaluation of Microbial Culture and Antibiogram in Patients With Head and Neck Infections Who Referred to Shahid Rajaee Hospital of Shiraz Between 1392 to 1398

Ghorbani

Faryabi

2021

Preprint

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Background: Head and neck infections happen due to different reasons and different microorganisms are responsible for them. These infections can be treated with various antibiotics. The purpose of this study was to specify most frequent etiology of infection, dominant bacterial species and most effective antibiotic in patients with head and neck infections who referred to Shahid Rajaee hospital of Shiraz.Methods: This study has been carried out in cross-sectional pattern from 2019-May to 2020-Oct in Oral & Maxillofacial Ward of Rajaee Hospital of Shiraz. Consent to access data and archive files was taken from the ethics committee of Shiraz University of Medical Sciences. Age, sex, etiology of infection, bacterial species, sensitivity or resistance reaction to Antibiotics and most frequently used antibiotic in patients who referred to this ward between 1392-Apr to 1398-Mar were collected on the basis of laboratory’s results. Data were analyzed with Chi-Square test.Results: statistical analysis showed that, 56 of patients were men (54.9%) and 46 were women (45.1%). The average of age was 38+/−17 and the minimum age was 6 and maximum age was 73. The most frequent etiology was odontogenic infections. Moreover, there was no statistically significant relationship between etiology and bacterial species (p-value=0.38) and Cefazolin had the most frequency in odontogenic infection group. Top three frequent bacterial species were respectively: Staphylococcus DNase & Coagulase Negative, Enterococci Sp., Streptococci Viridians and Klebsiella Sp. . There was no statistically significant relationship between bacterial species and sex (p-value=0.55). 94 (48.7 %) of bacterial species had Sensitive reaction to antibiotics. 21 (10.9 %) of them had Intermediate reactionand 78 (40%) of them had Resistant reaction and Cefazolin had the most frequency in sensitive group.Conclusion: The dominant bacterial species in head and neck infections are Staphylococcus DNase & coagulase negative. And, Cefazolin had the most sensitive reaction in odontogenic infections.

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“…De acordo com estudos, as pessoas mais afetadas pela AL geralmente apresentam entre 20 e 60 anos de idade, com predomínio no sexo masculino em uma relação de 2:1 4 . A etiologia normalmente está associada à presença de órgãos dentários cariados e/ou não vitais, infecções pós operatórias, doenças periodontais e pericoronarite 5 . Embora a infecção dentária seja sua principal origem, os profissionais também devem estar cientes de outras causas, tais como lacerações orais, fraturas mandibulares, infecção de glândulas salivares, abscessos peritonsilares e piercings na língua 6 .…”

Section: Introductionunclassified