Epidemiology and impact of HIV coinfection with Hepatitis B and Hepatitis C viruses in Sub-Saharan Africa

Matthews, Philippa C.; Geretti, Anna María; Goulder, Philip; Klenerman, Paul

doi:10.1016/j.jcv.2014.05.018

Cited by 158 publications

(176 citation statements)

References 134 publications

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“…37 Conversely, existing evidence points out that HBV and HCV coinfections are associated with worse outcomes for HIV-positive patients. [37][38][39] In addition, HBV/HCV coinfection may accelerate liver disease progression and increase the risk of hepatocellular carcinoma. 40 Thus the question of whether the interplay among HIV, HBV, and HCV infections influences Cryptosporidium infection is important.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Determinants of Cryptosporidium Infection in an Underdeveloped Rural Region of Southwestern China

Yang

Zhou

Cheng

et al. 2017

The American Society of Tropical Medicine and Hygiene

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Abstract. Few studies have focused on the epidemiology of Cryptosporidium in resource-challenged settings in China. We report a community-based cross-sectional study to investigate the prevalence of Cryptosporidium infection and its risk factors and associations with hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infections. The prevalence of Cryptosporidium infection was 12.6% (95% confidence interval = 11.0-14.3). Individuals living in households with ≥ 5 family members and raising domestic pigs tended to have a greater risk of Cryptosporidium infection. In addition, Cryptosporidium infection was significantly associated with HBV infection. There were no significant associations of Cryptosporidium infection with HIV viral load and HBV viral load. Further studies are needed to determine the association of Cryptosporidium infection with HBV infection. BACKGROUND

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Section: Discussionmentioning

confidence: 99%

Prevalence and Determinants of Cryptosporidium Infection in an Underdeveloped Rural Region of Southwestern China

Yang

Zhou

Cheng

et al. 2017

The American Society of Tropical Medicine and Hygiene

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“…Plus de la moitié des patients ont été mis sous traitement à un stade avancé de la maladie alors que les directives de l'OMS préconisent que la prise en charge des patients infectés par le VIH doit commencer si possible avant le stade sida. Il est maintenant à craindre que la maladie hépatique progressive puisse menacer le succès des programmes de traitement antirétroviraux dans les pays en développement, où les tests de surveillance du VHC et du VHB ne sont pas encore systématiques chez les patients infectés et l'utilisation du TARV ne tient pas généralement compte de ces co-infections (20), d'où la nécessité de la détermination de ces statuts.…”

Section: Discussionunclassified

Profil clinique et immunologique des patients infectés par le VIH à l’initiation du traitement antirétroviral à Douala

Essomba¹,

Ngahane

Nida

et al. 2015

Bull. Soc. Pathol. Exot.

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“…In fact, two billion people worldwide are infected with hepatitis B virus, over 350 million suffer from chronic liver disease, including 60 million in Africa, and, every year, between 500,000 and 700,000 people die there from [1].…”

Section: Introductionmentioning

confidence: 99%

“…The World Health Organization (WHO) estimates that 57% of cases of liver cirrhosis and 78% of primary liver carcinomas result from a hepatitis B or C virus [1].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of HBs Antigen, and HCV and HIV Antibodies in a Young Male Population in Cameroon

Noah¹,

Andoulo²,

Essoh³

et al. 2015

OJGas

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Introduction: According to WHO estimates, 57% of cases of liver cirrhosis and 78% of primary liver carcinoma are caused by a hepatitis B or C virus. This study aimed to assess the prevalence of these diseases and HIV among a young male population, according to region. Methods: This was a descriptive cross-sectional study conducted from 17 February to 31 March 2014 in the ten administrative regions of Cameroon. The study included male subjects of Cameroonian nationality aged at least 18 and at most 23, and living in the regions concerned. It excluded subjects that did not match the age, gender, and nationality criteria. For each subject, 10 ml of blood was collected in a dry tube. After centrifugation at 3000 RPM for 5 minutes, the serum was collected for the detection of viral infections. For subjects that tested positive, a confirmatory test was conducted. Results: In total, 4367 subjects were selected, with an average age of 20.46 (+/− 1.17) years. The prevalence of hepatitis B virus stood at 13.01% (with 95% CI: 12.03% -14.05%). That of viral hepatitis C was 0.30% (95% CI: 0.17% -0.52%). Co-infection with hepatitis B and C viruses was 0.05% (95% CI: 0.01% -0.18%). The prevalence of HIV infection was 1.01% (95% CI: 0.74% -1.36%). Conclusion: The overall prevalence of HBsAg in the population of young males is high. It tallies with the early vertical and horizontal modes of transmission that prevail in our environment.

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Epidemiology and impact of HIV coinfection with Hepatitis B and Hepatitis C viruses in Sub-Saharan Africa

Cited by 158 publications

References 134 publications

Prevalence and Determinants of Cryptosporidium Infection in an Underdeveloped Rural Region of Southwestern China

Prevalence and Determinants of Cryptosporidium Infection in an Underdeveloped Rural Region of Southwestern China

Profil clinique et immunologique des patients infectés par le VIH à l’initiation du traitement antirétroviral à Douala

Prevalence of HBs Antigen, and HCV and HIV Antibodies in a Young Male Population in Cameroon

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