Epidemiology and economic burden of osteoporosis in Switzerland

Svedbom, Axel; Ivergård, M; Hernlund, E; Rizzoli, René; Kanis, John А.

doi:10.1007/s11657-014-0187-y

Cited by 97 publications

(81 citation statements)

References 7 publications

(5 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Osteoporosis (OP) is a systemic disease of skeleton characterized by reduction of bone mass and disruption of bone architecture, resulting in reduced bone strength and increased risk of fragility fractures which represent the key clinical symptom of OP [1,2]. Based on etiology, OP is divided into 3 types: primary, secondary and idiopathic OP.…”

Section: Introductionmentioning

confidence: 99%

Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats

Zhang¹,

Min²,

Wang³

et al. 2016

Trop. J. Pharm Res

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats

Zhang¹,

Min²,

Wang³

et al. 2016

Trop. J. Pharm Res

View full text Add to dashboard Cite

show abstract

“…Bone mineral density (BMD, in g/cm 2 ), BMC (in grams), body fat (in percentages) and fat-free mass (FFM; in kilograms) were assessed using a dual-energy x-ray absorptiometry scanner subjects not involved in this study) and all scans were carried out in a temperature-controlled laboratory at the university.…”

Section: Bone Mineral Variablesmentioning

confidence: 99%

“…1,2 Although less common in pediatric populations, development of osteoporosis has been linked to peak bone mass gained during early life. 3,4 There is a natural decrease in bone mass during later life and, therefore, adolescents who present lower peak bone mass have an increased likelihood of developing osteoporosis during adulthood.…”

Section: Introductionmentioning

confidence: 99%

Somatic maturation and the relationship between bone mineral variables and types of sports among adolescents: cross-sectional study

et al. 2017

View full text Add to dashboard Cite

CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS:The study was composed of 93 adolescents (12 to 16.5 years old), divided into three groups: no-sport group (n = 42), soccer/basketball group (n = 26) and swimming group (n = 25). Bone mineral density and content were measured using dual-energy x-ray absorptiometry and somatic maturation was estimated through using peak height velocity. Data on training load were provided by the coaches. RESULTS: Adolescents whose PHV occurred at an older age presented higher bone mineral density in their upper limbs (P = 0.018). After adjustments for confounders, such as somatic maturation, the swimmers presented lower values for bone mineral density in their lower limbs, spine and whole body. Only the bone mineral density in the upper limbs was similar between the groups. There was a negative relationship between whole-body bone mineral content and the weekly training hours (β: -1563.967; 95% confidence interval, CI: -2916.484 to -211.450). CONCLUSION: The differences in bone variables attributed to sport practice occurred independently of maturation, while high training load in situations of hypogravity seemed to be related to lower bone mass in swimmers.RESUMO CONTEXTO E OBJETIVO: O pico de velocidade de crescimento (PVC) constitui importante evento maturacional durante a adolescência, afetando o tamanho do esqueleto. O objetivo do estudo foi comparar variáveis ósseas em adolescentes praticantes de diferentes modalidades esportivas, bem como identificar se diferenças nas variáveis ósseas atribuídas à prática esportiva são dependentes do estado da maturação somática. DESENHO E LOCAL: Estudo transversal, Universidade Estadual Paulista (UNESP).MÉTODOS: O estudo foi constituído por 93 adolescentes (12 a 16,5 anos), divididos em três grupos: grupo sem envolvimento esportivo (n = 42), futebol/basquete (n = 26) e natação (n = 25). A densidade e conteúdo mineral ósseo foram mensurados utilizando absortiometria de raio-x de dupla energia e a maturação somática foi estimada através do uso do PVC. Informações sobre volume de treinamento foram fornecidas pelos treinadores. RESULTADOS: Adolescentes com idade tardia no PVC apresentaram maiores valores de densidade mineral óssea em membros superiores (P = 0,018). Após ajustes por variáveis de confusão, como a maturação somática, os nadadores apresentaram menores valores de densidade mineral óssea em membros inferiores, coluna e corpo inteiro. Apenas a densidade mineral óssea de membros superiores foi similar entre os grupos. Existiu relação negativa entre conteúdo mineral ósseo de corpo inteiro e tempo de treino semanal (β: -1563.967; 95%...

show abstract

“…It is a major public health problem which affects numerous people worldwide, and imposes significant mental stress and economic burden on family and society [2]. The etiology of OP may be primary, secondary or idiopathic [3].…”

Section: Introductionmentioning

confidence: 99%

Effect of polygonimitin C on bone formation and resorption in human osteoblast-like MG63 cells

Shi¹,

Yang²,

Li³

et al. 2017

Trop. J. Pharm Res

View full text Add to dashboard Cite

show abstract

Epidemiology and economic burden of osteoporosis in Switzerland

Cited by 97 publications

References 7 publications

Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats

Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats

Somatic maturation and the relationship between bone mineral variables and types of sports among adolescents: cross-sectional study

Effect of polygonimitin C on bone formation and resorption in human osteoblast-like MG63 cells

Contact Info

Product

Resources

About