Epidemiology and comorbidity of psoriasis in children

“…In germany the prevalence is 0.4% 2 , whereas in India it is 12.5% 3 . the prevalence also increases with age, being lower in patients one year old (0.12%), but much more common at 18 years of age (1.2%) 4 . Despite the frequency of psoriasis, epidemiological studies in this age group are scarce and there is no published data from Mexico.…”

Section: Introductionmentioning

confidence: 99%

Psoriasis in Children and Adolescents: Epidemiological Study of 280 Patients from Mexico

Tovar‐Garza

Meza-Reséndiz

Guevara‐Gutiérrez

et al. 2017

RIC

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“…Genel nüfusun %1-2'sini etkileyen hastalık çocukluk çağı dermatozlarının %4'ünü oluşturmaktadır (11). Hastaların %10'nunda hastalığın başlangıcı 10 yaşından ve %2'sinde ise 2 yaşından öncedir (6,12). Avustralya, Orta Doğu ve Danimarka'da yapılan çalışmalarda ortalama görülme yaşı 5 yaş ve altı iken Hindistan'da 419 olguluk bir çalışmada 6-10 yaş aralığı olarak tespit edilmiştir (2).…”

Section: Discussionunclassified

“…K/E oranını 2/1 olarak bildiren ve hastalığın kızlarda daha erken yaşlarda başladığını öne süren çalışmalar bulunmaktadır (3,9,12). 358 hastanın incelendiği bir çalışmada da K/E oranı 1:1.06 olarak tespit edilmiştir (7).…”

Section: Discussionunclassified

The Retrospective Evaluation of Childhood Psoriasis Clinically and Demographic Features

Karadağ¹,

Bilgili²,

Çalka³

et al. 2013

tdd

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Objective: This study was aimed to define the clinical and demographic findings of psoriasis in childhood. Methods: In this retrospective study, the data from 64 children with psoriasis admitted at the our dermatology clinic between January 2007 and January 2011 were included whose data were fully. Results: Of the patients, 37 (57.8%) were boys and 27 (42.2%) were girls. Mean age of the children was 10.08 ±3.98 years (3-16). In 10 (15%) cases, a positive family history was detected. The most frequent localizations at onset were trunk (46.9%), scalp (28.1%), knee-elbow (10.9%) and extremities (7.9%), respectively. The most commonly seen clinical types were plaque (68.8%), guttate (20.3%), palmoplantar (9.4%), pustular (1.6%), respectively. Nine children had nail involvement. Out of all patients, 21.9% had upper respiratory tract infections and 9.4% had emotional stres. Four cases were diagnosed with depression. Of the cases, two cases were on non-steroid anti-inflammatory medication, and 4 of them were on antibiotics. Systemic treatments were given to 21.9% of the cases besides topical treatments. Conclusion:The epidemiological studies of psoriasis during childhood period for different countries have been reported. In this study, the ratio shows differences when compared to those previous studies. There are few epidemiologic studies for Turkey. We believe that further epidemiological studies including large number of patients' groups will contribute the diagnosis and treatment of the disease. Key words: Psoriasis, retrospective Sonuç: Çocukluk çağında görülen Psoriasisle ilgili farklı ülkeleri kapsayan çeşitli epidemiyolojik çalışmalar mevcuttur ve bu çalışmalarda bildirilen oranlar arasında farklılıklar bulunmaktadır. Ülkemizden bildirilen az sayıda epidemiyolojik çalışma mevcuttur. Daha geniş hasta gruplarını içeren çalışmalarla sağlanacak verilerin hastalığın tanı ve tedavisine katkıda bulunacağını düşünmekteyiz.

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“…It is estimated that the disease begins before children reach 16 in 25-45% of cases and before age 2 in 2% of patients. [2][3][4] The disease comes in many different clinical forms. In children, most cases are of the plaque variety, followed by the guttata form.…”

Section: Introductionmentioning

confidence: 99%

Psoríase eritrodérmica refratária em criança com excelente resposta ao etanercepte

Fraga

Paim

Follador

et al. 2011

An. Bras. Dermatol.

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Psoriasis affects 0.12% to 0.71% of all chil dren. Erythrodermic pso ria sis is an uncom mon but serious disor der, occur ring in less than 1.5% of cases. Tumor necro sis fac tor-alpha bloc kers (TNF-α) are a new class of drugs used to treat mode ra te to seve re pso ria sis refrac tory to con ven tio nal the ra pies. Etanercept is a TNFα recep tor fusion pro tein, appro ved by the FDA for trea ting juve ni le rheu ma toid arth ri tis. We pre sent the case of a 7-year-old suf fe ring from pla que pso ria sis since 8 months old which evol ved into eryth ro der ma refrac tory to cyclos po ri ne and metho tre xa te. Patient res pon ded excel lently to eta ner cept, with no adver se side effects. Keywords: Child; Psoriasis; Therapy Resumo: A pso ría se aco me te 0,12% a 0,71% da popu la ção infan til, sendo que a forma eri tro dér mi ca, grave e rara, ocor re em menos de 1,5% dos casos. Os anta go nis tas do Fator de Necrose Tumoral-α (TNF-α) cons ti tuem nova clas se de dro gas, uti li za da para tra ta men to da pso ría se grave a mode ra da, refra tá ria às tera pias con ven cio nais. O Etanercepte é uma pro teí na de fusão do recep tor do TNF-α, apro va da pelo Food and Drug Administration para tra ta men to da artri te reu ma toi de juve nil no grupo infan til. Apresentamos um caso de crian ça com 7 anos de idade, com pso ría se em placa desde 8 meses de vida, que evo luiu para eri tro der mia refra tá ria a ciclos po ri na e meto tre xa to, com exce len te res pos ta ao eta nercep te, sem fei tos adver sos. Palavras-chave: Criança; Psoríase; Terapêutica ©2011 by Anais Brasileiros de Dermatologia CASE REPORT INTRODUCTIONPsoriasis is a chronic systemic inflammatory disorder which affects 1-3% of the world´s population. A population-based study 1 reveals that the annual incidence of childhood psoriasis is 33.2 cases per 100,000 children. Child psoriasis affects 0.71% of the population under 18 and its prevalence increases linearly with age, from 0.12% in 1 year-olds to 1.2% in 18 yearolds. It is estimated that the disease begins before children reach 16 in 25-45% of cases and before age 2 in 2% of patients.

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Epidemiology and comorbidity of psoriasis in children

Abstract: Psoriasis is a common disease in children. Like in adults, it is associated with significant comorbidity. Increased attention should be paid to the early detection and treatment of patients affected.

Cited by 399 publications

References 32 publications

Psoriasis in Children and Adolescents: Epidemiological Study of 280 Patients from Mexico

Psoriasis in Children and Adolescents: Epidemiological Study of 280 Patients from Mexico

The Retrospective Evaluation of Childhood Psoriasis Clinically and Demographic Features

Psoríase eritrodérmica refratária em criança com excelente resposta ao etanercepte

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