The Retrospective Evaluation of Childhood Psoriasis Clinically and Demographic Features

Abstract

Objective: This study was aimed to define the clinical and demographic findings of psoriasis in childhood. Methods: In this retrospective study, the data from 64 children with psoriasis admitted at the our dermatology clinic between January 2007 and January 2011 were included whose data were fully. Results: Of the patients, 37 (57.8%) were boys and 27 (42.2%) were girls. Mean age of the children was 10.08 ±3.98 years (3-16). In 10 (15%) cases, a positive family history was detected. The most frequent localizations at onset were trunk (46.9%), scalp (28.1%), knee-elbow (10.9%) and extremities (7.9%), respectively. The most commonly seen clinical types were plaque (68.8%), guttate (20.3%), palmoplantar (9.4%), pustular (1.6%), respectively. Nine children had nail involvement. Out of all patients, 21.9% had upper respiratory tract infections and 9.4% had emotional stres. Four cases were diagnosed with depression. Of the cases, two cases were on non-steroid anti-inflammatory medication, and 4 of them were on antibiotics. Systemic treatments were given to 21.9% of the cases besides topical treatments. Conclusion:The epidemiological studies of psoriasis during childhood period for different countries have been reported. In this study, the ratio shows differences when compared to those previous studies. There are few epidemiologic studies for Turkey. We believe that further epidemiological studies including large number of patients' groups will contribute the diagnosis and treatment of the disease. Key words: Psoriasis, retrospective Sonuç: Çocukluk çağında görülen Psoriasisle ilgili farklı ülkeleri kapsayan çeşitli epidemiyolojik çalışmalar mevcuttur ve bu çalışmalarda bildirilen oranlar arasında farklılıklar bulunmaktadır. Ülkemizden bildirilen az sayıda epidemiyolojik çalışma mevcuttur. Daha geniş hasta gruplarını içeren çalışmalarla sağlanacak verilerin hastalığın tanı ve tedavisine katkıda bulunacağını düşünmekteyiz.

Psoriasisli çocuk hastaların klinik ve demografik özelliklerinin retrospektif olarak değerlendirilmesi

“…The study conducted in India revealed that 31% of the patients had nail involvement (10). As a result of the study conducted with pediatric patients in our country by Karadağ et al, nail involvement ratio was stated as 9% (4). In our study the nail involvement ratio was 18.57% (8 boys, 5 girls).…”

“…Another study conducted in Australia with 1262 patients revealed this ratio as 71% (11). A study conducted by Karadağ et al in our country resulted in 10% family history ratio (4). In our study, the positive family history ratio was 31.4%.…”

“…For many patients with psoriasis other autoimmune diseases such as morfea and vitiligo are also accompanying (5). Karadağ et al Stated that the comorbidity was no encountered during their study but hypothyroid (in 2 patients) and atopic dermatitis (in 3 patients) were observed (4). In our study, we did not observed accompanying comorbidity.…”

“…The most frequent clinical type was detected as plaque as a result of the study conducted in Australia with 1262 patients (34%) (11). As a result of the study conducted by Karadağ et al with 64 pediatric patients, the clinical type ratios were detected as follows respectively: plaque (68.8%), guttate (20.3%), palmoplantar (9.4%) and pustular (6%) (4). In our study the distribution of clinical type ratios were as follows: 65.7% plaque, 21.4% guttate, 1.42% pustular and 8.57% palmoplantar.…”

“…However, nowadays it has been accepted that the reaction develops as epidermal hyperplasia as a result of activation of immune system in focal skin areas (3). Environmental factors affect the pathogenesis and some environmental factors such as climate, smoking, stress, trauma, medications, and infections triggers the initiation of the disease (4). Plaque, guttate, pustules, palmoplantar, erythrodermic, inverse, diaper, nail and oral/mucosal psoriasis variations are seen at childhood psoriasis.…”