Epidemiology and Comorbidity in Children with Psoriasis and Atopic Eczema

Abstract

Background: First studies have shown that juvenile psoriasis is associated with an increased prevalence of comorbidity. Objectives: We carried out a data analysis to characterise the profiles of comorbidity in children with psoriasis and atopic eczema. Methods: Prevalence data were derived from the database of a German statutory health insurance company according to ICD-10 codes L40 (psoriasis) and L20 (atopic eczema) of children up to 18 years insured in 2009. Results: Data sets included 1.64 million persons and 293,181 children. 1,313 children = 0.45% (0.42-0.47) had a diagnosis of psoriasis and 30,354 = 10.35% (10.24-10.47) had a diagnosis of atopic eczema. Obesity, hyperlipidaemia, arterial hypertension and diabetes were more often diagnosed in children with psoriasis in comparison to all children without psoriasis and to those with atopic eczema. Conclusion: Children with psoriasis and atopic eczema show different and specific patterns of comorbidity which should be detected early and treated adequately.

Association between psoriasis and asthma risk: A meta-analysis

“…8,13,19 -22,25 The details of the selected studies are listed in Table 1, with a total 66,772 psoriasis cases and 577,415 controls to investigate the risk of susceptibility asthma in patients with psoriasis. There were three retrospective cohort studies 8,13,19 and three cross-sectional cohort studies. 20 -22,25 As for ethnicity, three studies investigated white populations, 19,20,22,25 three studies investigated Asian populations.…”

“…There were three retrospective cohort studies 8,13,19 and three cross-sectional cohort studies. 20 -22,25 As for ethnicity, three studies investigated white populations, 19,20,22,25 three studies investigated Asian populations. 8,13,21 All the studies included patients of all ages, and two studies provided detailed incidences of asthma at different ages.…”

“…Three studies were deemed to be high quality (7-9 stars), 8,13,21 whereas the other three studies were deemed to be of medium quality (4 -6 stars). 19,20,22,25 …”

Obesity and Psoriasis: Can Bariatric Surgery Trigger Psoriasis?

“…Further, a meta-analysis of 16 observational studies on the epidemiological associations between psoriasis and obesity included a total of 2.1 million patients (201,831 psoriasis patients) identified OR for obesity among patients with mild psoriasis was 1.46 (95% CI: 1.17-1.82) and 2.23 (95% CI: 1.63-3.05) for severe psoriasis [5]. Additionally, obesity was found more common in children with psoriasis than in controls in two recent large population studies [6,7].…”

Assessment of Level of Knowledge and Beliefs Toward Psoriasis Among Community In Almadina Almonawara City, 2016.

“…Between 4.2% and 69% of all patients suffering from psoriasis develop nail changes (8)(9)(10) . Individuals with psoriasis are reported to be at increased risk of developing other serious clinical conditions such as cardiovascular and other noncommunicable diseases [11,12] . Disfiguration, disability and marked loss of productivity are common challenges for people with psoriasis.…”