Epidemiology and analysis of potential risk factors of high‐risk human papillomavirus (HPV) in Shanghai China: A cross‐sectional one‐year study in non‐vaccinated women

Niu, Jiaxin; Pan, Shuting; Wei, Yingting; Hong, Zubei; Gu, Liyi; Di, Wen; Qiu, Lihua

doi:10.1002/jmv.27453

Cited by 11 publications

(17 citation statements)

References 43 publications

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“…Consistent with other studies ( Niu et al, 2022 ), the current study shows that women with a high school education or lower, have a higher risk of HPV infection than women with a higher education level. Additionally, socioeconomic status is closely related to the incidence of cervical cancer, particularly in developing countries.…”

Section: Discussionsupporting

confidence: 92%

“…Moreover, although the total positivity rate of HPV infection in China is ∼21.69%, it varies between economically developed and underdeveloped areas. For instance, a study in Shanghai included 6,619 women, of whom the HR-HPV infection rate was 9.5% ( Wang et al, 2021 ), whereas another study in Jiangsu included 36,500 women and reported a 28.95% HR-HPV infection rate ( Niu et al, 2022 ). Still further, a study in Guangxi from 2016 to 2021 included 41,140 women, for whom the overall HR-HPV infection rate was 18.10% ( Wei et al, 2022 ).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Status and epidemiological characteristics of high-risk human papillomavirus infection in multiple centers in Shenyang

Yang

Zhang²,

Cui³

et al. 2022

Front. Microbiol.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Status and epidemiological characteristics of high-risk human papillomavirus infection in multiple centers in Shenyang

Yang

Zhang²,

Cui³

et al. 2022

Front. Microbiol.

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“…Our findings are compatible with those reported in the literature. 25 Similar to a previous study, 27 in our study, unmarried individuals were 4.48 times more likely to be HR-HPV-positive than those who were married. It should also be taken into account that singles can have multiple partners.…”

Section: Discussionsupporting

confidence: 88%

An Investigation the Relationship of Vaginal Microbial Bacteria Species with Bacterial Vaginosis and High-Risk Human Papillomavirus

Öner

Kaleli

Kaleli̇

2022

Kocaeli Üniversitesi Sağlık Bilimleri Dergisi

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Objective: This study was aim to investigate the relationship of vaginal bacterial species with High-Risk Human Papillomavirus (HR-HPV) and bacterial vaginosis (BV).Methods: One hundred and twenty-one women were included in the study. Gram stain was performed for the diagnosis of BV and evaluated according to the Nugent score. HR-HPV diagnosis was made by real-time PCR . Detection of vaginal microbial species and Gardnerella vaginalis subtypes were also performed by real-time PCR.Results: The prevalence of BV was found as 38.8%. The mean number of species was found significantly higher in BV-positive samples compared to BV-intermediate and BV-negative samples (p=0.001). Lactobacillus iners (p=0.036), BVAB2 (p=0.043), Provetella spp. (p=0.015), Leptotrichia/Sneathia (p=0.001), Megaspheara (p=0.048) were found to be associated with bacterial vaginosis. Gardnerella vaginalis subtypes were evaluated in 50 randomly selected samples. The most common strain that was found was “clade 4”. The prevalence of HR-HPV was 9.9%. HPV 16 was the most common HR-HPV type (58.3%). There was no significant difference between the mean value of Lactobacillus sp. HR-HPV-positive and negative samples (p=0.23). No association was found between the specified species and HR-HPV-positive samples (p=0.436).Conclusion: Bacterial diversity was greater in BV-positive patients and BV was significantly associated with Lactobacillus iners, Megaspheara, BVAB2, Provetella spp. and Leptotrichia / Sneathia.

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“…HR-HPV prevalence rate in our study was 11.65%, which was 2.78 times the prevalence for LR-HPV infection and consistent with a recent national investigation in 2017 (12.1%) [ 27 ], lower than that in Jiangxi (19.53%) [ 28 ] and Shandong (24.2%) [ 29 ]. It is generally believed that the oncogenic HPV infection rate in developed economic areas was lower than in relatively underdeveloped areas [ 30 ]. The feasible reason for the lower HR-HPV prevalence rate in our study may be also associated with relatively developed economy and people,s advanced and better health awareness in Shanghai.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of cervicovaginal human papillomavirus infection and genotype distribution in Shanghai, China

Xiang

Dai

et al. 2022

Virol J

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Background The evaluation of human papillomavirus (HPV) prevalence rate dynamics and genotype distribution could support the adoption of more targeted prevention and treatment of cervical cancer. We aimed to assess the infection status and genotype characteristics of HPV among gynecological outpatients in Shanghai, China. Methods Clinical specimens were collected from patients attending gynaecological department of the Putuo Hospital, Shanghai University of Traditional Chinese Medicine, between January 2015 and December 2019. The cervicovaginal infection of 17 high-risk genotypes and 10 low-risk genotypes were analyzed by Luminex-based multiple assays. Results The overall HPV infection rate was 18.81% (95% CI 18.31–19.30%) in Shanghai city, with high-risk, low-risk and mixed high- and low-risk HPV prevalence being 11.65% (95% CI 11.24–12.06%), 4.19% (95% CI 3.94–4.44%) and 2.96% (95% CI 2.74–3.17%), respectively. The five most prevalent high-risk genotypes were HPV-52 (2.95%), HPV-16 (2.34%), HPV-58 (2.07%), HPV-53 (1.67%) and HPV-39 (1.36%). The most common low-risk genotype was HPV-61 (1.52%), followed by HPV-6 (1.29%) and HPV-81 (1.19%). Moreover, the coverage of HPV genotype by nonavalent vaccine was 10.42%, and non-vaccine-covered high-risk genotype was 7.70%. The 15–24 years age group demonstrated the highest HPV prevalence (43.14%), and significant differences were observed among different age groups (P < 0.001). Conclusions This study revealed the HPV prevalence and genotype distribution among women in Shanghai city, which could serve as guidance for HPV vaccination and preventative strategies against cervical cancer in this area.

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Epidemiology and analysis of potential risk factors of high‐risk human papillomavirus (HPV) in Shanghai China: A cross‐sectional one‐year study in non‐vaccinated women

Cited by 11 publications

References 43 publications

Status and epidemiological characteristics of high-risk human papillomavirus infection in multiple centers in Shenyang

Status and epidemiological characteristics of high-risk human papillomavirus infection in multiple centers in Shenyang

An Investigation the Relationship of Vaginal Microbial Bacteria Species with Bacterial Vaginosis and High-Risk Human Papillomavirus

Prevalence of cervicovaginal human papillomavirus infection and genotype distribution in Shanghai, China

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