Epidemiological trends of women’s cancers from 1990 to 2019 at the global, regional, and national levels: a population-based study

Abstract

Background Every year around the world, more than 2 million women are diagnosed with breast cancer and genital tract cancers. However, there are rare studies comprehensively describing the global and regional trends of incidence and mortality of women’s cancers. Methods To study the burden and trend of women’s cancers, we conducted this cross-sectional study based on the epidemiologic data of Global Burden of Disease 2019. In this study, female patients with breast cancer, cervical cancer, ovarian cancer, and uterine cancer worldwide from 1990 to 2019 were involved. The incidence, death, and disability-adjusted life-year (DALY) were used to measure the outcomes of women’s cancers. The estimated annual percentage change (EAPC) was calculated to assess the changing trend of cancer burden. Results Among the four women’s cancers, the burden of female breast cancer was highest. During the past 30 years, the incidence, death, and DALY of female breast cancer kept increasing worldwide. In most regions especially developing countries, cervical cancer was the second most common women’s cancer. At the same time, ovarian cancer and uterine cancer occurred less frequently. Generally, the age-standardized incidence rates (ASIRs) of breast cancer, ovarian cancer, and uterine cancer were positively correlated to sociodemographic index (SDI) value. In contrast, the ASIR of cervical cancer was negatively correlated to SDI value. Conclusions Our study indicates that the incidence and mortality of women’s cancers have geographical variations and change along with SDI value. The results might be helpful to policy-makers to allocate healthy resources to control women’s cancers.

Disease Burden and Attributable Risk Factors of Ovarian Cancer From 1990 to 2017: Findings From the Global Burden of Disease Study 2017

“…Previous paper about the incidence and mortality burden of ovarian cancer confirmed our findings (23). Besides, the latest research about the global disease burden of women cancer revealed that the incidence, deaths, and DALYs of ovarian cancer were 294,420, 198,410, and 5,359,740, respectively in 2019 globally which showed increases from 2017 (24). These findings could be helpful to the allocation of the limited health service resources as well as the evaluation of interventions or programs.…”

The Global, Regional, and National Burden and Trends of Infective Endocarditis From 1990 to 2019: Results From the Global Burden of Disease Study 2019

“…Global Burden of Disease 2019 (GBD 2019) provided the information about the burdens of 369 diseases and injuries along with 87 risk factors in the globe, different geographic areas, and 204 countries and territories ( 15 , 16 ) and the detailed introduction was shown in Supplementary File 1 , which aimed at quantifying the relative magnitude of health loss due to risk factors, injuries and diseases by age, gender, SDI (sociodemographic index) and geographic location at a specific point in time. Data on infective endocarditis burden from 1990 to 2019 including its incidence, death, DALYs, and their corresponding age-standardized rates (ASRs), were acquired from the Global Health Data Exchange GBD Results Tool ( http://ghdx.healthdata.org/gbd-results-tool ) (date of data extraction, 21 April of 2021).…”

The global, regional, and national disease burden of breast cancer attributable to low physical activity from 1990 to 2019: an analysis of the Global Burden of Disease Study 2019

“…Breast cancer mortality rates have been declining globally in the last three decades [ 1 ], principally owing to improvements in treatment and the early detection by mammography screening [ 2 , 3 ], while the number of breast cancer deaths and disability-adjusted life years (DALYs) have continued to increase [ 4 ], which perhaps can be attributed to the population growth and inadequacy of prevention strategies [ 2 ]. Keeping physically active is one of the most important recommendations presented by the World Cancer Research Fund, which suggests staying at least moderately physically active and limiting sedentary habits [ 5 ].…”