Epidemiological studies of equine herpesvirus 1 (EHV-1) in Thoroughbred foals: a review of studies conducted in the Hunter Valley of New South Wales between 1995 and 1997

Gilkerson, James R.; Whalley, J. M.; Drummer, Heidi E.; Studdert, M. J.; Love, Daria N.

doi:10.1016/s0378-1135(99)00057-7

Cited by 88 publications

(62 citation statements)

References 15 publications

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“…Epidemiological investigations of acute respiratory disease have confirmed that equine influenza virus (EIV) and equine herpesvirus 1 and 4 (EHV‐1/4) are important causes of both clinical and subclinical infection among young horses in racing yards and stud farms, and those returning from equestrian events 1, 2, 3, 4, 5. Disease and suboptimal performance following infection with these viruses can result in significant financial loss.…”

Section: Introductionmentioning

confidence: 99%

Concurrent vaccination against equine influenza and equine herpesvirus – a practical approach

Gildea

Higgins²,

Johnson

et al. 2016

Influenza Resp Viruses

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BackgroundThere is a lack of information concerning concurrent administration of vaccines against equine influenza virus (EIV) and equine herpesvirus 1 and 4 (EHV‐1/4).ObjectivesThe primary objective of this study was to determine the impact of the concurrent use of EIV and EHV‐1/4 vaccines in Thoroughbred racehorses on their humoral immune response to EIV.MethodsThis study was carried out on a population of 30 horses using an inactivated whole‐virus EIV vaccine and an inactivated EHV‐1/4 vaccine. Horses were randomly allocated to vaccination group A or B. Horses in group A were vaccinated against EIV and EHV‐1/4 2 weeks apart. Horses in group B were vaccinated against EIV and EHV‐1/4 on the same day. Whole‐blood samples were collected on the day of vaccination and 2 weeks and 6 weeks post‐vaccination. Antibody levels against EIV and EHV‐1/4 were measured using the single radial haemolysis and serum neutralisation test, respectively.ResultsThe pattern of EIV antibody response post‐vaccination was similar for both groups. Highest EIV antibody levels were recorded 2 weeks post‐vaccination, and a significant decrease in antibody level was observed 4 weeks later. Horses in group B demonstrated a significantly higher EIV antibody response post‐vaccination. Overall, there was no significant difference in EHV‐1/4 antibody response between the two groups post‐vaccination.ConclusionIn this study, concurrent vaccination against EIV and EHV‐1/4 increased the response to EIV and did not compromise the humoral immune response to EHV‐1/4.

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Section: Introductionmentioning

confidence: 99%

Concurrent vaccination against equine influenza and equine herpesvirus – a practical approach

Gildea

Higgins²,

Johnson

et al. 2016

Influenza Resp Viruses

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“…This work showed that foals become infected with EHV-1 as young as 30 days old [168]. More recent work has identified EHV-1 shedding in foals as young as 22 days old [169].…”

Section: Epidemiology and Conclusionmentioning

confidence: 60%

“…In one study of foals born to unvaccinated mares, 24% of foals had EHV-1 antibodies attributable to maternally derived antibodies. Of the remaining at-risk foals, 66.7% demonstrated seroconversion to EHV-1 prior to weaning [168]. Further work also identified new cases of EHV-1 in weaned foals, suggesting that ongoing horizontal transmission amongst foals occurs post weaning [170].…”

Section: Epidemiology and Conclusionmentioning

confidence: 95%

“…suggesting that the cycle of EHV-1 between mares and foals and subsequently between foals and between weanlings is a 'silent' cycle in many cases [171]. Thus the control of EHV-1 infection in very young foals is a key factor to manage the disease [168,171]. When foals are infected early in life and establish latency, they may become sources of infection for their own offspring later in life.…”

Section: Epidemiology and Conclusionmentioning

confidence: 99%

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Equine Herpes Virus-1: Virus, Immunity and Vaccines

Paillot¹,

Case²,

Ross³

et al. 2008

TOVSJ

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Equine Herpes virus-1 (EHV-1) is one of the most common respiratory pathogens of the horse. EHV-1 induces several clinical signs of disease ranging in severity, from mild respiratory distress to abortion in pregnant mares, neonatal foal death and neuropathogenic disorders. This review details some aspects of EHV-1 biology, its life cycle and pathogenicity in the natural host. Protective immunity stimulated by natural EHV-1 infection, which is short lived and depends of both humoral and cellular immune responses, will also be treated here. Vaccination remains today one of the best options to fight EHV-1 infection and several different strategies of vaccination that have been investigated and developed over the past decades will be presented in this report.

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“…Em estudos epidemiológicos realizados na Austrália, Gilkerson et al (1999aGilkerson et al ( , 1999b O HVE-1 é altamente contagioso e sua transmissão é horizontal, ou seja, ocorre pela inalação de aerossóis provenientes do trato respiratório ou pela ingestão de alimento e água contaminados por secreções (ALLEN, 2002b;BRYANS, 1986;KOTAIT, 1991;MUMFORD, 1994 A principal porta de entrada do HVE-1 é a mucosa do trato respiratório, na qual a infecção primária se instala pela multiplicação viral local (ALLEN, 2002b;KOTAIT, 1991;OSTLUND, 1993).…”

Section: Figuraunclassified

Infecção experimental em cavalos pelo herpesvírus eqüino tipo 1: aspectos clínicos e detecção do agente pela reação em cadeia pela polimerase

Mori¹

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Epidemiological studies of equine herpesvirus 1 (EHV-1) in Thoroughbred foals: a review of studies conducted in the Hunter Valley of New South Wales between 1995 and 1997

Cited by 88 publications

References 15 publications

Concurrent vaccination against equine influenza and equine herpesvirus – a practical approach

Concurrent vaccination against equine influenza and equine herpesvirus – a practical approach

Equine Herpes Virus-1: Virus, Immunity and Vaccines

Infecção experimental em cavalos pelo herpesvírus eqüino tipo 1: aspectos clínicos e detecção do agente pela reação em cadeia pela polimerase

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