Epidemiological Significance of Asymptomatic Carriers of COVID-19

Базыкина, Е. А.; Троценко, О. Е.

doi:10.31631/2073-3046-2020-19-6-69-73

Cited by 2 publications

(2 citation statements)

References 37 publications

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“…по результатам исследований, проведенных в испании, выявляемость антител к SARS-CoV-2 составила 9,8 %, причем у 40 % диагноз новой коронавирусной инфекции установить не удалось [8]. показана существенная роль носителей SARS-CoV-2 в распространении инфекции, активном вовлечении асимптоматических форм новой коронавирусной инфекции в эпидемический процесс [9]. в италии среди мр крупного онкологического центра бессимптомное течение выявлено у 9,4 % медработников, причем у 31,8 % из них выявлены рнк SARS-CoV-2 в респираторных мазках, что свидетельствует об активном инфекционном процессе [10].…”

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“…во-первых, «носительство» вируса, когда на протяжении всего инфекционного периода отсутствуют как клинические симптомы COVID-19, так и типичные изменения легочной ткани при компьютерной томографии. во-вторых, выделяют так называемое предсимптоматическое носительство (пациенты в инкубационном периоде заболевания) с наличием рнк SARS-CoV-2 в респираторных мазках и развитием с течением времени клинических проявлений инфекции [9,[18][19][20][21]. это подтверждает важность проведения серологического мониторинга в мо различного профиля.…”

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Experience in Studying Herd and Individual Immunity to the SARS-CoV-2 Virus in Medical Workers

Решетникова

Агафонова

Тюрин

et al. 2021

Problemy Osobo Opasnykh Infektsii

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The aim was to study SARS-CoV-2 immunity among medical workers in Kazan.Materials and methods. Studied were serum samples from 348 medical workers from 10 medical organizations in Kazan, divided into groups according to the level of the alleged risk of infection of employees. To determine IgG, a two-stage direct version of the solid-phase ELISA and the test-system “SARS-CoV-2-IgG-ELISA-BEST” (Russia) were used.Results and discussion. At the time of the study and over the previous three months, the examined medical workers had no symptoms of acute respiratory viral infection or respiratory tract infections; there were negative results of examining nasopharyngeal/ oropharyngeal swabs for the presence of SARS-CoV-2 RNA. Seroprevalence for IgG to SARS-CoV-2 virus for different medical organizations in Kazan ranged within the scope of 3.3–30.8 % and averaged 16.4 %. The wide variation in seroprevalence values in medical workers of different medical organizations may indicate different levels of intensity of professional contacts and the effectiveness of anti-epidemic measures in these medical organizations. Among medical workers with seropositive results, the prevalence of persons with a very high coefficient of positivity (49.1 %) is observed, which characterizes high level of antiviral antibodies. The presence of a high proportion of seropositive individuals among medical workers, who have had an asymptomatic form of COVID-19 confirms the high intensity of the latent epidemic process, which must be taken into account when organizing preventive measures, including vaccination.

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Experience in Studying Herd and Individual Immunity to the SARS-CoV-2 Virus in Medical Workers

Решетникова

Агафонова

Тюрин

et al. 2021

Problemy Osobo Opasnykh Infektsii

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Organization for laboratory diagnosis of SARS-COV-2 in the conditions of an anti-tuberculosis institution

Kotova,

Safonova,

Freiman

et al. 2023

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Introduction. In connection with the spread of a new coronavirus infection COVID-19 since 2020, measures have been taken in the city of Moscow to widely diagnose the causative agent of COVID-19. A laboratory PCR department was opened in the State Budgetary Healthcare Institution «MNPC for the fight against tuberculosis of the DZM», taking into account the available material and human resources. Purpose of the study: To generalize the experience of organizing the laboratory service of an anti-tuberculosis institution in the city of Moscow during the spread of a new coronavirus infection. Results. Human and material resources have made it possible to maintain the quality and availability of laboratory diagnostics of biological material from patients receiving treatment at the Moscow Regional Research and Practical Center for Combating Tuberculosis, DZM, during the COVID-19 pandemic. In the period 2020-2022 in total, 90,102 studies of biological material (smears) were carried out by RT-PCR in order to detect COVID-19 RNA. Starting from June 2020 to the present, the PCR department of the KDL Clinic 2 has been studying the direct detection of Covid-19 RNA in biological material using molecular genetic methods based on reverse transcription and polymerase chain reaction (RT-PCR) and the identification of specific immunoglobulin classes IgM and IgG to coronavirus antigens in blood serum (plasma) by the method of immunochemiluminescent analysis (ICLA) of both persons receiving treatment at the State Budgetary Institution of Healthcare Center for Combating Tuberculosis Moscow, and employees.

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Epidemiological Significance of Asymptomatic Carriers of COVID-19

Cited by 2 publications

References 37 publications

Experience in Studying Herd and Individual Immunity to the SARS-CoV-2 Virus in Medical Workers

Experience in Studying Herd and Individual Immunity to the SARS-CoV-2 Virus in Medical Workers

Organization for laboratory diagnosis of SARS-COV-2 in the conditions of an anti-tuberculosis institution

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