Epidemiological Characterization of Covid-19 Cases in Maranhão: A Brief Analysis

Almeida, Joelson dos Santos; Cardoso, Jonas Alves; Cordeiro, Eduardo Costa; Lemos, Messias; Araújo, Telma Maria Evangelista de; Sardinha, Ana Hélia de Lima

doi:10.26694/repis.v6i0.10477

Cited by 11 publications

(7 citation statements)

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“…In our demographic analysis we found a predominance of females in both groups (cases and controls). This corroborates with the profile found in other studies published in Brazil [ 30 ] whereas in Wuhan, China, 56% of the cases were male individuals [ 31 ]. It is emphasized that Brazilian population estimative for 2020 shows a slight female dominance [ 32 ].…”

Section: Discussionsupporting

confidence: 92%

Higher frequency of hepatic steatosis at CT among COVID-19-positive patients

et al. 2020

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Purpose Recent studies have demonstrated that obesity is significantly associated with increased disease severity, hospitalizations and mortality in COVID-19, with a potential role in the pathogenesis and prevalence in the new pandemic. The association with hepatic steatosis, however, a condition closely related to obesity within the spectrum of systemic metabolic dysfunctions, remains to be elucidated. We aimed to evaluate the frequency of hepatic steatosis as incidentally detected in chest CT examinations of COVID-19 positive patients in comparison to non-infected controls. Methods A retrospective study was performed with 316 patients (204 RT-PCR positive; 112 RT-PCR negative and chest CT negative). Steatosis was measured with placement of a single ROI in the right lobe of the liver (segments VI-VII) and defined as a liver attenuation value ≤ 40 HU. Results The frequency of hepatic steatosis was higher in the RT-PCR positive group in comparison to controls (31.9% vs. 7.1%, p < 0.001). Logistic linear regression analysis showed a 4.7 times odds of steatosis in the COVID-19 positive group as compared to controls after adjusting for age and sex (OR 4.698; 95% IC 2.12-10.41, p < 0.001). Conclusion A significantly higher prevalence of steatosis was found among COVID-19 positive individuals. These findings are in accordance with other recent studies linking obesity and COVID-19 infection, as there is an intricate relationship between liver steatosis, metabolic syndrome and obesity. Further studies are required to confirm if such association remains after accounting for multiple variables, as well as possible relationships with disease severity and worst clinical outcomes.

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Section: Discussionsupporting

confidence: 92%

Higher frequency of hepatic steatosis at CT among COVID-19-positive patients

et al. 2020

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“…These data were similar to those of a study on the epidemiological profile of SARS-CoV-2 notifications, which also found a predominance of males, age ≥60 y and comorbidities. 13 …”

Section: Discussionmentioning

confidence: 99%

“…Similar results were presented in a study carried out in Maranhão at the beginning of the pandemic, in which the municipality of São Luís had the highest mortality for the period (81 deaths). 13 …”

Section: Discussionmentioning

confidence: 99%

“… 24 Another study evaluated the distribution of deaths due to COVID-19 in the period from March to April 2020 and has also found that the city of São Luís had the highest number of deaths. 13 …”

Section: Discussionmentioning

confidence: 99%

“…Studies aimed at detecting COVID-19 spatiotemporal death clusters are essential for health systems and services since their findings can contribute to a better allocation of resources and assist in the implementation of effective decisions aimed at disease control and surveillance. 12 From this perspective, there is a need for investigations that can be used to support strategies against COVID-19, 13 especially considering the scarcity of studies with spatiotemporal analysis of deaths related to this disease in Brazil.…”

Section: Introductionmentioning

confidence: 99%

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Deaths due to COVID-19 in a state of northeastern Brazil: spatiotemporal distribution, sociodemographic and clinical and operational characteristics

Silva

Brito

Sousa

et al. 2021

Transactions of the Royal Society of Tropical Medicine and Hygiene

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Background The detection of spatiotemporal clusters of deaths by coronavirus disease 2019 (COVID-19) is essential for health systems and services, as it contributes to the allocation of resources and helps in effective decision making aimed at disease control and surveillance. Thus we aim to analyse the spatiotemporal distribution and describe sociodemographic and clinical and operational characteristics of COVID-19-related deaths in a Brazilian state. Methods A descriptive and ecological study was carried out in the state of Maranhão. The study population consisted of deaths by COVID-19 in the period from 29 March to 31 July 2020. The detection of spatiotemporal clusters was performed by spatiotemporal scan analysis. Results A total of 3001 deaths were analysed with an average age of 69 y, predominantly in males, of brown ethnicity, with arterial hypertension and diabetes, diagnosed mainly by reverse transcription polymerase chain reaction in public laboratories. The crude mortality rates the municipalities ranged from 0.00 to 102.24 deaths per 100 000 inhabitants and three spatiotemporal clusters of high relative risk were detected, with a mortality rate ranging from 20.25 to 91.49 deaths per 100 000 inhabitants per month. The headquarters was the metropolitan region of São Luís and municipalities with better socio-economic and health development. Conclusions The heterogeneous spatiotemporal distribution and the sociodemographic and clinical and operational characteristics of deaths by COVID-19 point to the need for interventions.

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