Epidemiological, Biological and Etiological Profile of Thrombocytopenia Diagnosed at the Hematology Laboratory of the Arrazi Hospital of the University Hospital Center Mohammed Vi-Marrakesh- Prospective Study (March 2021-August 2021)

Abstract

Study objectives: This study attempts to describe the epidemiological and biological profiles as well as the common etiologies of thrombocytopenia in patients admitted to University Hospital center Mohammed VI in Marrakesh, Morocco, over a period of six months between March 2021 and August 2021. Patients and methods: This is a prospective study of 673 patients hospitalized in the University Hospital center -Mohammed VI-Marrakesh between March and August 2021 whose admission blood tests show thrombocytopenia. Results: Thrombocytopenia was found in 673 patients, mainly from the intensive care unit (28%) and the department of hematology & oncology (16%), the sex ratio was 1.3 with a male predominance of 58%, the average age of our patients was 37.1 years. On biological plan, prothrombin (PT) and CRP were the two most noticed disturbed biological markers in our series, at 50% and 79% respectively, the etiological profile of our patients demonstrated a predominance of peripheral thrombocytopenia at 83.2%, The most frequent causes were infectious (43%), bacterial, viral or parasitic, followed by anomaly of distribution of platets (12%) and immunological thrombocytopenia (9%). Conclusion: Our study shows that thrombocytopenia is a frequent biological anomaly that can affect both sexes, of any age, it is most often multifactorial, but the main cause is infection, requiring a correlation of epidemiological, clinical and biological profiles in order to adapt the treatment.