Epidemiological Assessment of Neglected Diseases in Children: Lymphatic Filariasis and Soil-Transmitted Helminthiasis

Aguiar-Santos, Ana Maria; Medeiros, Zulma; Bonfim, Cristine Vieira do; Rocha, Abraham; Brandão, Eduardo; Miranda, Tereza; Oliveira, Paula A.; Sarinho, Emanuel Sávio Cavalcanti

doi:10.1016/j.jpedp.2012.11.004

Cited by 5 publications

(4 citation statements)

References 22 publications

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“…MWAKITALU et al [6] reported lymphatic filariasis infection, disease and transmission in Tanga, Tanzania. AGUIAR-SANTOS et al [7] reported lymphatic filariasis and intestinal parasitic infection of school-aged children in Pernambuco, Brazil. In India, microfilariae Wuchereria bancrofti attacked breast woman [8,9].…”

Section: Introductionmentioning

confidence: 99%

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

Ernawan

Sasmita

2017

J. Ilmiah Aplikasi Isotop dan Radiasi

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Filariasis as part of the neglected tropical disease is one of the health problems in the world. Filariasis divided into onchocerciasis (river blindness) and lymphatic filariasis or elephantiasis. This disease caused by filarial nematode parasites Onchocerca volvulus, Wuchereria bancrofti, Brugia malayi and Brugia timori. Filariasis transmitted by several mosquito genera as the vector. Indonesia as endemic filariasis, agreed on plays a role on World Health Organization (WHO) global filariasis elimination in 2020. Sterile insect technique (SIT) is a potential method which can be applied to filariasis elimination program by controlling the mosquito population. Basic principles of SIT involve mass rearing of species target, sterilization process using gamma-rays and releasing sterile male insect into a target area. SIT combined with other methods under one management as Area-wide Integrated Pest Management (AW-IPM) to increasing effectiveness and successful filariasis elimination program in Indonesia. Filariasis elimination program in Indonesia has several challenges and needed public participation to achieve program goals. Key words : filariasis, Indonesia, sterile insect technique (SIT) ABSTRAKFilariasis sebagai bagian dari penyakit tropis yang terbengkalai merupakan salah satu masalah kesehatan di dunia. Filariasis dibagi menjadi onchocerciasis dan filariasis limfatik atau kaki gajah. Penyakit ini disebabkan oleh parasit nematoda filarial Onchocerca volvulus, Wuchereria bancrofti, Brugia malayi dan Brugia timori. Filariasis ditularkan oleh beberapa genera nyamuk sebagai vektor. Indonesia sebagai endemik filariasis, sepakat memainkan peran dalam eliminasi filariasis global yang diagendakan oleh world health organization (WHO) pada tahun 2020. Teknik serangga mandul (TSM) adalah metode potensial yang dapat diterapkan pada program eliminasi filariasis dengan mengendalikan populasi nyamuk. Prinsip dasar SIT melibatkan pembiakan populasi target secara massal, proses sterilisasi menggunakan sinar gamma dan melepaskan serangga jantan steril ke daerah sasaran. TSM dapat dikombinasikan dengan metode lain di bawah satu manajemen terpadu, yaitu area-wide integrated pest management (AW-IPM) untuk meningkatkan efektivitas dan keberhasilan program eliminasi filariasis di Indonesia. Program eliminasi filariasis di Indonesia memiliki beberapa tantangan dan kebutuhan partisipasi masyarakat untuk mencapai tujuan program.

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Section: Introductionmentioning

confidence: 99%

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

Ernawan

Sasmita

2017

J. Ilmiah Aplikasi Isotop dan Radiasi

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“…Recife and its metropolitan region remain as the only endemic region for lymphatic filariasis in Brazil (Freitas et al, 2008;Fontes et al, 2012;Aguiar-Santos et al, 2013). Different factors contribute to this endemism, such as a combination of weather conditions and unplanned urbanization, which result in high population densities of Cx.…”

Section: Discussionmentioning

confidence: 99%

An unsettling explanation for the failure of skatole‐baited ovitraps to capture Culex mosquitoes

et al. 2018

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Culex mosquitoes are primarily found in temperate and tropical regions worldwide where they play a crucial role as main vectors of filarial worms and arboviruses. In Recife, a northeast city in Brazil, high densities of Culex quinquefasciatus are often found in association with human populated areas. In marked contrast to another part of the city, field tests conducted in the neighborhood of Sítio dos Pintos showed that trapping of mosquitoes in skatole-baited ovitraps did not differ significantly from captures in control (water) traps. Thus, classical and molecular taxonomic approaches were used to analyze the Culex species circulating in Sítio dos Pintos. Results obtained from both approaches agreed on the cocirculation of Culex quinquefasciatus and Culex nigripalpus in three different areas of this neighborhood. What was initially considered as an unexpected failure of this lure turned out to be a more unsettling problem, that is, the first report in Recife of Culex nigripalpus, a vector of Venezuelan equine encephalitis virus and West Nile virus. Unplanned urbanization processes close to remnants of the Atlantic forest, such as observed in Sítio dos Pintos, may have contributed to the introduction of Cx. nigripalpus in urban areas.

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“…In 2017, the proportion of the population in endemic areas worldwide requiring MDA was 52.4%, with 465.4 million people treated in 37 countries with reported cases. Brazil is a GPELF signatory and conducted MDA between 2003 and 2017 in three municipalities of Pernambuco State: Recife, Olinda, and Jaboatão dos Guararapes, with the exclusive use of diethylcarbamazine (DEC) [7]. Treatment was performed in focal areas, meeting the criteria established by each municipality [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of lymphatic filariasis in endemic area of Brazil where mass drug administration is not required

Silva

Xavier

Silva

et al. 2019

Pathogens and Global Health

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Mass drug administration (MDA) is the main counter-transmission strategy of the Global Programme to Eliminate Lymphatic Filariasis. In endemic countries, there are areas where MDA is not required. However, there is no standard approach in these areas, and studies are important to evaluate the epidemiological status. This study aimed to investigate lymphatic filariasis and strategies developed for its control in an area where MDA is not required. Together with the 2018 morbidity evaluation, a survey was conducted using point-of-care immunochromatographic test-AD12 tests for diagnostic screening in an area where MDA is not required. The methodology also included desk research based on Health Department reports of the control activities for lymphatic filariasis during 2003-2016. Among the 934 cases investigated in 2018, there was a 0.64% prevalence of circulating filarial antigen positive, comprising five adults and one 2-year-old child. Six patients aged 39-63 years had filarial disease. Fourteen surveys have already been conducted as control activities, and since 2009, there have been no positive cases. This study showed that the prevalence of antigenemia decreased from 2.97% in 2003 to 0.64% in 2018. Moreover, the transmission of filariasis infection was under control in this area. Our study provides insights into the surveillance phase by identifying areas of low transmission and where MDA is not required. Although we have not identified cases of filarial infection, there is a need to provide services that will provide assist those already affected with morbidity and help reduce and prevent disability.

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Epidemiological Assessment of Neglected Diseases in Children: Lymphatic Filariasis and Soil-Transmitted Helminthiasis

Cited by 5 publications

References 22 publications

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

An unsettling explanation for the failure of skatole‐baited ovitraps to capture Culex mosquitoes

Evaluation of lymphatic filariasis in endemic area of Brazil where mass drug administration is not required

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