Epidemic Infantile Diarrhea and Vomiting

Bact. Coli in Infantile Diarrhoea

“…Although alpha and beta coli have been shown to be sensitive in vitro to chloramphenicol, it has been demonstrated that this antibiotic is neither more nor less effective in those cases from which these strains have been is6lated than in those whose stool cultures are negative for these organisms. Although this finding seems contrary to the reported results of Rogers et al (1949), Smellie (1950), and Laurell et al (1951), it is fair to comment that each of these was a preliminary report involving very few cases.…”

Detection of a New Serotype of Escherichia Coli, E. Coli O127: B8, Associated With Acute Diarrhea in Infants

“…Similar findings have been made in Germany by Beeuwkes, Hodenpijl, and ten Seldam (1949); Braun (1950Braun ( , 1951; Laurell et al (1951); Krepler and Zischka (1952); Zischka (1952); Opitz (1952); and Hoster (1953); in France by Buttiaux et al (1951) and Clement et al (1953); in Denmark by aufmann and Dupont (1950) and Dupont (1951); in Jerusalem by Drimmer-Herrnheiser and Olitzki (1951); in Australia by Williams (1951); in Israel by Rappaport and Henig (1952); in Mexico by Olarte and Varela (1952); and in Ceylon by Schmid and Velaudapillai (1952). In the United States, bacteriological and clinical studies with certain serotypes of E. coli associated with diarrhea in infants date from 1950, and have been made, until recently, primarily in the laboratories of Doctor Erwin Neter and Doctor William W. Ferguson: Neter and Shumway (1950); 1952a,b;1953a,b);; Gorzynski and Neter (1953); Neter and Zalewski (1953); Ferguson, Jennings, and Gottshall (1951); Ferguson and June (1952); Modica, Ferguson, and Ducey (1952); and June, Ferguson, and Worfel (1953).…”

Bacterial infection in the fetus and newborn.

“…Some value in drug treatment has been shown in controlled trials (Medical Research Council, 1953), as well as in prevention of cross-infection and relapse and stopping epidemics generally (Laurell et al, 1951;Stulberg et al, 1955;Valman and Wilmers, 1969), though the carrier state frequently persists and may be prolonged. The heavy environmental contamination at such times is conducive to spread (Rogers, 1951) unless nursing and medical techniques are of the most scrupulous.…”